Feb 24, 2025
Tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs) were recognized to cause endocrine adverse reactions (EARs). However, combination therapy-associated EARs are still unclear.This was a retrospective study...
Read MoreFeb 24, 2025
TNFα has long stood as a hallmark feature of both inflammatory bowel disease (IBD) and arthritis with its therapeutic potential demonstrated in neutralizing monoclonal antibody treatments such as Infliximab. Due to the high...
Read MoreFeb 17, 2025
Predicting long-term outcomes in liver transplantation remain a challenging endeavor. This research aims to harness the power of deep learning to develop an advanced prognostic model for assessing long-term outcomes, with a...
Read MoreFeb 17, 2025
Infectious bone defects pose a significant challenge in orthopedics by hindering healing and vascularization. This study explored the impact of fibroin thermosensitive hydrogel on osteogenesis, inflammatory response, and...
Read MoreFeb 17, 2025
Monosomy X (45,X) is associated with Turner syndrome and pregnancy loss in humans, but the underlying mechanisms remain unclear. We therefore undertook an exploratory study of the transcriptomic landscape of clinically relevant...
Read MoreFeb 17, 2025
Unplanned hospital readmissions after surgery are substantial drivers of expenditure and bed occupancy within the healthcare system. As a result, any targeted interventions that reduce readmission in this population can have a...
Read MoreFeb 17, 2025
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) are m⁶A readers that stabilize target mRNAs by recognizing the GG(m⁶A)C sequence. While previous studies have explored the biological mechanisms of IGF2BPs in lung...
Read MoreFeb 17, 2025
Despite the existence of numerous clinical practice guidelines (CPGs) for cystic fibrosis (CF), there is limited understanding of their credibility and consistency. This systematic review aims to comprehensively evaluate the...
Read MoreFeb 17, 2025
A disintegrin and metalloproteinase 17 (ADAM-17) has multiple pathophysiological functions in Alzheimer’s disease (AD). However, the clinical relevance of ADAM-17 in AD is not clear yet.This study aims to investigate the...
Read MoreFeb 17, 2025
Anxiety and depression are highly prevalent in youth and can cause significant distress and functional impairment. The presence of maternal anxiety and depression are well-established risk factors for child internalizing...
Read MoreFeb 17, 2025
Co-rumination, characterized by excessively discussing problems and dwelling on negative affect within a dyadic friendship, has been associated with adolescents’ symptoms of depression, anxiety and perceived...
Read MoreFeb 17, 2025
Biotic and abiotic stresses threaten crop growth and yield. Agrochemicals are an important way to mitigate biotic stress, while frequent low utilization and potential environmental risk affect their sustainable use. In order to...
Read MoreFeb 17, 2025
Given the close relationship between lipids and gestational diabetes mellitus(GDM), the present study sought to examine the association between the triglyceride high-density cholesterol-glucose body index(TyHGB) and the risk of...
Read MoreFeb 17, 2025
The purpose of this study was to evaluate the effects of the digital-conventional integrated teaching method on prosthetics preclinically in full crown preparation courses.Fifty-eight undergraduate dental students were randomly...
Read MoreFeb 17, 2025
To evaluate the reliability and validity of the Health Literacy Scale for HPV Vaccination among parents of girls aged 9-14. A total of 830 parents of girls in grades 3-8 were sampled using convenience sampling in March-April...
Read MoreFeb 17, 2025
Sleeve gastrectomy is safe and effective in patients with left ventricular assist devices (LVADs) and morbid obesity to improve candidacy for transplantation and increase survival rates. Literature describing warfarin...
Read MoreFeb 17, 2025
Children on the autism spectrum with minimal speech are generally provided with augmentative and alternative communication (AAC) systems that represent vocabulary using picture symbols (i.e., color line drawings). However, there...
Read MoreFeb 17, 2025
CT is considered the gold standard to assess bone morphology, whereas MRI is the imaging modality of choice to assess soft tissue. To reduce the ionising radiation exposure of the patient from CT, new MRI technologies have been...
Read MoreFeb 17, 2025
To evaluate the effectiveness of an evidence-based pre-, peri- and postoperative rehabilitation pathway (i.e. the REACT rehabilitation pathway) on disability in patients undergoing lumbar fusion surgery (LFS), compared to usual...
Read MoreFeb 17, 2025
Sarcopenia, characterized by age-related loss of muscle mass and function, significantly impacts the quality of life of older adults. This condition is prevalent among elderly patients with hip fractures.To investigate the...
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