Dec 9, 2024
Ectopic fat is reduced by effective weight management, but difficult to assess clinically.We evaluated paired data on 42 participants in the intervention group of the Diabetes Remission Clinical Trial (DiRECT) at baseline, 12...
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The PCSK9 protein binds to LDL receptors (LDLR), leading to their degradation and reduced expression on cell surfaces. This decreased the clearance of LDL cholesterol from the bloodstream, thereby increasing the risk of coronary...
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Recent studies suggest the existence of an idiopathic pulmonary arterial hypertension (IPAH) phenotype affecting mostly patients with a smoking history, characterised by low diffusion capacity for carbon monoxide (D) without...
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This study investigates the association between climate and childhood asthma in Australia. Data from the Longitudinal Study of Australian Children (LSAC) was used to analyse this association in children who were 6-15 years...
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Interleukin-2 (IL-2) is a well-known cytokine that plays a crucial role in stimulating immune cells, including natural killer (NK) cells and cytotoxic T cells. It has been studied as an immunotherapy for a variety of diseases,...
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Soft tissue filler injection is the second most commonly performed cosmetic procedure worldwide, with augmentation rhinoplasty being the most common filling surgery in Asian countries because Asians predominantly have a low...
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Cognitive impairments are prevalent during remission in bipolar disorder (BD), but existing cognitive screening tools are time- and resource-intensive. Digital, web-based options can facilitate detection and monitoring of these...
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The Mobile Device Proficiency Questionnaire (MDPQ) is a well-established, reliable, and valid instrument to measure basic and advanced mobile device skills among older adults. We offer a German adaptation of the MDPQ and report...
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We conducted a retrospective cohort study of women with suspected tubal factor infertility who underwent vaginal natural orifice endoluminal surgery (vNOTES) chromopertubation and adnexal anatomy assessment at a large referral...
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Currently, there is little research on successful talent development environments (TDEs) focusing on women and girls. In response, the main aim of the present study was to compare TDEs of age-specific national teams for girls...
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Stereotactic ablative radiotherapy (SABR) has become a key technique in management of spine metastases. With improved control over treatment plan dosimetry, there is a greater need for accurate patient positioning to guarantee...
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To assess the rate of macular blood flow decreasing in adults with and without posterior staphyloma (PS) using optical coherence tomography angiography (OCTA) and to identify risk factors associated with PS progression.This...
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To investigate the utility of diffusion-weighted magnetic resonance imaging (DW-MRI) in evaluating Gleason score (GS) 7 tumors before definitive radiotherapy (RT) and to explore its association with clinicopathological factors...
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This study aimed to investigate the dosimetric impact of deep-learning-based auto-contouring for clinical target volume (CTV) and organs at risk (OARs) delineation in prostate cancer radiotherapy planning. Additionally, we...
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The role of local ablative radiotherapy (stereotactic body radiotherapy (SBRT)/stereotactic radiosurgery (SRS)) in the management of metastatic breast cancer (mBC) patients remains unclear. This study aimed to assess the...
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To preliminarily evaluate the treatment efficacy of a temperature-adjustable cryotherapy device for chronic, recurrent blepharitis in dogs.Five dogs (eight eyes) of different breeds with blepharitis, which was unresponsive to...
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Clobazam (CLB) is an effective, safe and well-tolerated adjunctive treatment for refractory epilepsy. However, the cost-effectiveness of CLB in China remains unclear.The aim of this study was to evaluate the cost-effectiveness...
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Identifying factors associated with uncomplicated and complicated opioid use is essential, especially with regard to safety concerns in impaired kidney function. Literature about opioid prescription and their potential...
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New data and new antiretroviral drugs and formulations continue to become available for the prevention and management of HIV infection.To provide updated recommendations for HIV treatment and clinical management and HIV...
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Functional constipation (FC) is a common digestive disorder that affects patients’ quality of life and is closely associated with intestinal tumors. This study used a cross-sectional design to assess the changes of...
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