PubMed

Polygenic TB control and the sequence of innate/adaptive immune responses to infection: MHC-II alleles determine the size of the S100A8/9-producing neutrophil population.

Jul 15, 2024

Among several quantitative trait loci involved in tuberculosis (TB) control in mice, one was mapped within the chromosome 17 segment occupied by the H2 complex and another within the chromosome 3 segment comprising the S100A8/9...

Rectal organoid morphology analysis (ROMA) as a novel physiological assay for diagnostic classification in cystic fibrosis.

Jul 15, 2024

Diagnosing cystic fibrosis (CF) is not always straightforward, in particular when sweat chloride concentration (SCC) is intermediate and <2 CF-causing variants are identified. The physiological CFTR assays proposed in the...

Role of elective neck dissection in cT2N0 maxillary sinus squamous cell carcinoma.

Jul 15, 2024

Our objective was to examine the impact of elective neck dissection (END) on the prognosis of patients with cT2N0 maxillary sinus squamous cell carcinoma (MS-SCC) and to determine factors that predict the occurrence of occult...

Thyroid complications after hemopoietic stem cell transplantation in children and adolescents.

Jul 15, 2024

To evaluate the prevalence of thyroid dysfunction and its association with possible contributing factors related to diagnosis and treatment in children who received hematopoietic stem cell transplantation (HSCT) in the only...

Exploring the role of CBLB in acute myocardial infarction: transcriptomic, microbiomic, and metabolomic analyses.

Jul 15, 2024

Specific alterations in gut microbiota and metabolites have been linked to AMI, with CBLB potentially playing an essential role. However, the precise interactions remain understudied, creating a significant gap in our...

Impact of musculoskeletal disability limitations on the economic unmet dental needs in South Korea.

Jul 15, 2024

Musculoskeletal disability (MSD) has been identified as having a negative impact on oral health. Patients with MSD have a greater burden of medical expenses and are expected to have an Economic unmet dental need (UDN). This...

JACQLQ subjective symptom questionnaire score and clinical test results for patients with allergic conjunctival disease.

Jul 15, 2024

We investigated the relationship between subjective symptoms and objective findings in patients with allergic conjunctival diseases (ACD) and test results for tear total IgE (t-tIgE), conjunctival eosinophils (c-Eo), serum total...

Efficacy and safety of platelet-rich plasma and hyaluronic acid combination therapy for knee osteoarthritis: a systematic review and meta-analysis.

Jul 8, 2024

This study aimed to evaluate whether a combination of platelet-rich plasma (PRP) and hyaluronic acid (HA) is more effective and safer than injection alone for treating KOA.MEDLINE (PubMed), the Cochrane Library, EMBASE, and Web...

“Filler-Associated Acute Stroke Syndrome”: Classification, Predictive Modelling of Hyaluronidase Efficacy, and Updated Case Review on Neurological and Visual Complications.

Jul 8, 2024

The rising use of soft tissue fillers for aesthetic procedures has seen an increase in complications, including vascular occlusions and neurological symptoms that resemble stroke. This study synthesizes information on central...

Dislocated 4-haptic intraocular lens rescue with Gore-tex suture scleral re-fixation.

Jul 8, 2024

Dislocated IOL exchange conventionally involves manipulation within the anterior chamber which risks secondary injury to anterior chamber structures. We describe and evaluate a 4-haptic IOL rescue technique that avoids entering...

Long-term outcomes of canaloplasty and phaco-canaloplasty in the treatment of open angle glaucoma: a single-surgeon experience.

Jul 8, 2024

To evaluate and compare the long-term outcomes of canaloplasty and phaco-canaloplasty in the treatment of open angle glaucoma and assess the prognostic factors associated with surgical outcome.A 48-month retrospective analysis...

Improving prediction of blood cancer using leukemia microarray gene data and Chi2 features with weighted convolutional neural network.

Jul 8, 2024

Blood cancer has emerged as a growing concern over the past decade, necessitating early diagnosis for timely and effective treatment. The present diagnostic method, which involves a battery of tests and medical experts, is...

Psychological experience and coping strategies of pregnant women with acute pancreatitis: a qualitative descriptive study.

Jul 8, 2024

To clarify the psychological experience and coping strategies in patients with acute pancreatitis in pregnancy (APIP) and propose interventional measures to improve pregnancy outcomes in these women. With an increasing trend of...

Clinical applications of telemedicine services using a regional telemedicine platform for cancer treatment: a cross-sectional study.

Jul 8, 2024

Telemedicine is beneficial for improving treatment efficiency and reducing medical expenses of cancer patients. This study focuses on cancer patients participating in teleconsultations through a regional telemedicine platform in...

Editorial Perspective: Healthy body-Healthy mind? Does exercise benefit people with attention-deficit/hyperactivity disorder?

Jul 8, 2024

Attention-deficit/hyperactivity disorder (ADHD) stands out as one of the most prevalent neurodevelopmental disorders, significantly affecting daily functioning. However, finding a sustainable treatment strategy for ADHD remains...

Inhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in mice.

Jul 8, 2024

Kidney fibrosis is considered to be the ultimate aggregation pathway of chronic kidney disease (CKD), but its underlying mechanism remains elusive. Protein kinase C-delta (PKC-δ) plays critical roles in the control of growth,...

Validation of self-reported human papillomavirus vaccination in young adult men who have sex with men.

Jul 8, 2024

The Victorian Government introduced a time-limited human papillomavirus (HPV) catch-up program for gay, bisexual, and other men who have sex with men (GBMSM) aged ≤ 26 years in 2017-2019. We conducted a retrospective...

Suppression of host gene expression is associated with latent TB infection: a possible diagnostic biomarker.

Jul 8, 2024

The World Health Organization End TB strategy aims for a 90% reduction of tuberculosis (TB) incidence by 2035. Systematic testing and treatment of latent TB infection (LTBI) among contacts of active TB patients is recommended as...

A powerful machine learning approach to identify interactions of differentially abundant gut microbial subsets in patients with metastatic and non-metastatic pancreatic cancer.

Jul 8, 2024

Pancreatic cancer has a dismal prognosis, as it is often diagnosed at stage IV of the disease and is characterized by metastatic spread. Gut microbiota and its metabolites have been suggested to influence the metastatic spread...

The C-terminal proline-rich repeats of Enteropathogenic E. coli effector EspF are sufficient for the depletion of tight junction membrane proteins and interactions with early and recycling endosomes.

Jul 8, 2024

Enteropathogenic E. coli (EPEC) causes acute infantile diarrhea accounting for significant morbidity and mortality in developing countries. EPEC uses a type three secretion system to translocate more than twenty effectors into...

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