PubMed

Proceedings of the National Academy of Sciences of the United States of America 2018 06 11115(26) 6822-6827 doi 10.1073/pnas.1806308115 Abstract Novel reassortant avian influenza H7N9 virus and pandemic 2009 H1N1 (H1N1pdm) virus...

Nature communications 2018 06 069(1) 2197 doi 10.1038/s41467-018-04564-3 Abstract Eukaryotic cells employ the ribosome-associated quality control complex (RQC) to maintain homeostasis despite defects that cause ribosomes to...

PloS one 2018 06 1813(6) e0198166 doi 10.1371/journal.pone.0198166 Abstract Heavy alcohol consumption is an established risk factor for hypertension; the mechanism by which alcohol consumption impact blood pressure (BP)...

International journal of molecular sciences 2018 06 0619(6) pii 10.3390/ijms19061689 Abstract Parkinson’s disease (PD) is a progressively debilitating neurodegenerative disease characterized by α-synucleinopathy,...

Nature communications 2018 06 089(1) 2231 doi 10.1038/s41467-018-04651-5 Abstract CRISPR advances genome engineering by directing endonuclease sequence specificity with a guide RNA molecule (gRNA). For precisely targeting a gene...

Frontiers in oncology 2018 05 248() 161 doi 10.3389/fonc.2018.00161 Abstract Advances in chemotherapy and targeted therapies have improved survival in cancer patients with an increase of the incidence of newly diagnosed brain...

PLoS biology 2018 07 1616(7) e2005840 doi 10.1371/journal.pbio.2005840 Abstract Clustered, regularly interspaced, short palindromic repeat (CRISPR)-CRISPR-associated 9 (Cas9) genome editing is revolutionizing fundamental...

Nature communications 2018 07 139(1) 2724 doi 10.1038/s41467-018-05072-0 Abstract Identifying tumor antigen-specific T cells from cancer patients has important implications for immunotherapy diagnostics and therapeutics. Here,...

Genome biology 2018 07 1219(1) 88 doi 10.1186/s13059-018-1464-7 Abstract BACKGROUND DNA methylation is a heritable epigenetic mark, enabling stable but reversible gene repression. In mammalian cells, DNA methyltransferases...

Molecular cell 2018 06 2871(1) 56-72.e4 pii 10.1016/j.molcel.2018.06.003 Abstract Chromatin remodeling complexes play essential roles in metazoan development through widespread control of gene expression, but the precise...

Evidence-based complementary and alternative medicine : eCAM 2018 06 072018() 9521086 doi 10.1155/2018/9521086 Abstract Showering is the most common form of bathing worldwide. Whole-body immersion bathing in warm water (~40°C)...

Cell 173(2) 278-280 doi 10.1016/j.cell.2018.03.047 Abstract

Tropical medicine & international health : TM & IH 2011 10 0417(1) 135-8 doi 10.1111/j.1365-3156.2011.02885.x Abstract OBJECTIVE Internal use of ‘camphor’ is a potential public health concern in Accra. We...

Cell reports 24(2) 429-440 pii 10.1016/j.celrep.2018.06.042 Abstract Mycobacterium tuberculosis (Mtb) kills infected macrophages by inhibiting apoptosis and promoting necrosis. The tuberculosis necrotizing toxin (TNT) is a...

The New England journal of medicine 379(2) 138-149 doi 10.1056/NEJMoa1714021 Abstract BACKGROUND Recent Mycobacterium tuberculosis infection confers a predisposition to the development of tuberculosis disease, the leading killer...

Cell reports 24(2) 320-328 pii 10.1016/j.celrep.2018.06.047 Abstract The flavivirus genus comprises major human pathogens, such as Dengue (DENV) and Zika (ZIKV) viruses. RIG-I and MDA5 are key cytoplasmic pathogen recognition...

Neurobiology of stress 2018 05 199() 9-21 doi 10.1016/j.ynstr.2018.05.003 Abstract Microglia are the predominant immune cells of the central nervous system (CNS) that exert key physiological roles required for maintaining CNS...

Nature communications 2018 07 069(1) 2643 doi 10.1038/s41467-018-05067-x Abstract CRISPR-Cas9-based gene activation (CRISPRa) is an attractive tool for cellular reprogramming applications due to its high multiplexing capacity...

Journal of the International Society of Sports Nutrition 2018 07 0915(1) 31 doi 10.1186/s12970-018-0236-9 Abstract BACKGROUND Ketogenic diets (KD) have become a popular method of promoting weight loss. More recently, some have...

Nature communications 2018 07 069(1) 2641 doi 10.1038/s41467-018-05073-z Abstract RNA-based drugs depend on chemical modifications to increase potency and to decrease immunogenicity in vivo. Chemical modification will likely...