Nature communications 2018 06 089(1) 2231 doi 10.1038/s41467-018-04651-5 Abstract CRISPR advances genome engineering by directing endonuclease sequence specificity with a guide RNA molecule (gRNA). For precisely targeting a gene...
Read MoreFrontiers in oncology 2018 05 248() 161 doi 10.3389/fonc.2018.00161 Abstract Advances in chemotherapy and targeted therapies have improved survival in cancer patients with an increase of the incidence of newly diagnosed brain...
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Genome medicine 2018 04 1310(1) 27 doi 10.1186/s13073-018-0534-5 Abstract BACKGROUND The interplay...
Read MoreFrontiers in aging neuroscience 2018 04 1710() 109 doi 10.3389/fnagi.2018.00109 Abstract It has been 200 years since Parkinson disease (PD) was described by Dr. Parkinson in 1817. The disease is the second most common...
Read MoreThe New England journal of medicine 2018 04 16() doi 10.1056/NEJMoa1801005 Abstract Background First-line therapy for advanced non-small-cell lung cancer (NSCLC) that lacks targetable mutations is platinum-based chemotherapy....
Read MoreThe New England journal of medicine 2018 04 16() doi 10.1056/NEJMoa1716078 Abstract Background Antibodies that block programmed death 1 (PD-1) protein improve survival in patients with advanced non-small-cell lung cancer (NSCLC)...
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The New England journal of medicine 2018 04 16() doi 10.1056/NEJMoa1801946 Abstract Background...
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Nature communications 2018 04 139(1) 1448 doi 10.1038/s41467-018-03927-0 Abstract Off-target DNA...
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The New England journal of medicine 2018 04 15() doi 10.1056/NEJMoa1802357 Abstract Background The...
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Scientific reports 2018 04 168(1) 6030 doi 10.1038/s41598-018-24463-3 Abstract Aggregation of TAR...
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Frontiers in medicine 2018 03 125() 61 doi 10.3389/fmed.2018.00061 Abstract Geroscience, the new...
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Cell 173(2) 321-337.e10 pii 10.1016/j.cell.2018.03.035 Abstract Genetic alterations in signaling...
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Nature communications 2018 04 139(1) 1466 doi 10.1038/s41467-018-03731-w Abstract To accurately...
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Nature communications 2018 04 129(1) 1438 doi 10.1038/s41467-018-03939-w Abstract Autophagy is a...
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The New England journal of medicine 2018 04 13() doi 10.1056/NEJMoa1709691 Abstract Background Dry...
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Cell 121(4) 553-565 pii 10.1016/j.cell.2005.03.028 Abstract ATP hydrolysis is required for...
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Nature communications 2018 04 139(1) 1444 doi 10.1038/s41467-018-03614-0 Abstract The binding of...
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Cell 173(2) 371-385.e18 pii 10.1016/j.cell.2018.02.060 Abstract Identifying molecular cancer...
Read MoreCell 173(2) 386-399.e12 pii 10.1016/j.cell.2018.03.027 Abstract The role of enhancers, a key class of non-coding regulatory DNA elements, in cancer development has increasingly been appreciated. Here, we present the detection...
Read MoreJournal of the American Heart Association 2018 04 137(8) pii 10.1161/JAHA.118.008643 Abstract BACKGROUND Frailty predicts poorer outcomes and decreased anticoagulation use in patients with nonvalvular atrial fibrillation. We...
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