Apr 14, 2025
In clear aligner treatment (CAT), closure of the premolar space is achieved by reducing aligner length. Posterior anchorage preparation is effective in preserving molar angulation; however, the resulting distal tipping can...
Read MoreApr 14, 2025
Scoliosis considerably affects adolescents’ physical well-being and quality of life. Current research offers scant data concerning the correlation between abnormal posture, screen time, physical activity, and adolescent...
Read MoreApr 14, 2025
This study investigated static and dynamic pupillometry changes before and after ICL V4c implantation under varying light conditions. A prospective study of 210 high myopia patients undergoing V4c ICL implantation was conducted....
Read MoreApr 14, 2025
The performance of global large language models (LLMs), trained largely on Western data, for disease in other settings and languages is unknown. Taking myopia as an illustration, we evaluated the global versus Chinese-domain...
Read MoreApr 14, 2025
Acute myeloid leukemia (AML) is a hematological malignancy characterized by complex immune microenvironment. This study aims to identify immune-related prognostic biomarkers in AML.Multiple public sequencing datasets were...
Read MoreApr 14, 2025
Acute megakaryoblastic leukemia (AMKL) is a rare hematological malignancy in adults but children. Alternative splicing (AS) has been shown to affect hematological cancer progression, making splicing factors promising targets....
Read MoreApr 14, 2025
Chemoresistance is the most significant challenge affecting the clinical efficacy of the treatment of patients with gastric cancer (GC). Here we reported that transmembrane protein 160 (TMEM160) suppressed ferroptosis and...
Read MoreApr 14, 2025
Glioblastoma (GBM) is an aggressive Grade IV brain tumor with a poor prognosis. It results from genetic mutations, epigenetic changes, and factors within the tumor microenvironment (TME). Traditional treatments like surgery,...
Read MoreApr 14, 2025
Recently, we found, using a cigarette carcinogen-induced lung cancer model, that soy protein isolate (SPI) was superior to casein in preventing lung cancer. In this study, we have attempted to identify the component(s) within...
Read MoreApr 14, 2025
Birth weight (BW) is a key indicator of a newborn’s health, survival, and development. It is associated with the risk of childhood mortality and is also related to health, physical growth, emotional well-being, and...
Read MoreApr 14, 2025
Olaparib, an inhibitor of poly (ADP-ribose) polymerase (PARP), has demonstrated promising outcomes in treating HER2-negative early-stage breast cancer with BRCA mutations. However, a comprehensive evaluation of its...
Read MoreApr 14, 2025
Endoplasmic reticulum (ER) stress is increasingly recognized as a driver of cancer progression; however, the precise molecular mechanisms by which ER stress facilitates tumor metastasis remain incompletely understood. In this...
Read MoreApr 14, 2025
Chronic insomnia and obstructive sleep apnea commonly co-occur. Few studies have explored the neurophysiological and neurocognitive characteristics of COMISA, which could help guide improving treatment diagnostic tools and...
Read MoreApr 14, 2025
Chronic postsurgical pain (CPSP) is being increasingly recognized as an important clinical problem. The purpose of this prospective multicenter study was to evaluate the prevalence and risk factors of CPSP at 3 months after...
Read MoreApr 14, 2025
Substance use disorder (SUD) has been linked with social impairments. The social cognitive dysfunctions can further increase the risk of the development of SUD or relapse. Therefore, understanding the neural mechanism of...
Read MoreApr 14, 2025
The identification and intervention of Alzheimer’s Disease (AD) in its early-stage allows for the timely implementation of lifestyle modifications and therapeutic strategies. Although dysregulation of protein expression...
Read MoreApr 14, 2025
Attention deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder. Despite its significance, no large-scale epidemiological study assessing ADHD, and its associated comorbidities in children and...
Read MoreApr 14, 2025
The purpose of this study was to use the FDA Adverse Event Reporting System (FAERS) to detect and identify adverse events (AEs) related to sulfasalazine to provide a reference for clinical use.Four algorithms (ROR, PRR, BCPNN...
Read MoreApr 14, 2025
Cervical cancer constitutes a formidable health challenge imperiling the well-being and lives of women globally, particularly in underdeveloped nations. The survival rates among patients diagnosed with cervical cancer manifest...
Read MoreApr 14, 2025
The low immunogenicity of pancreatic cancer inhibits effective antitumor immune responses, primarily due to the immune evasion mediated by low expression of the major histocompatibility complex (MHC). Through comprehensive...
Read More
