PubMed

Multigenerational effects of individual and binary mixtures of two commonly used NSAIDs on Daphnia carinata.

Jan 6, 2025

Pharmaceuticals, including non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (IBU) and naproxen (NPX), are widely used for medical purposes but have also become prevalent environmental contaminants. However, there is...

Proposal: Bold New Indications for Transcatheter Pulmonary Flow Restrictors.

Jan 6, 2025

This proposal presents a proof of concept for the use of pulmonary flow restrictors (PFRs) based on MVP™-devices, drawing from clinical experience, and explores their potential role in the management of newborns with hypoplastic...

Demographic and clinical trends of young breast cancer patients from the national cancer database: disproportionate effect on minority populations.

Jan 6, 2025

There is an increasing incidence of young breast cancer (YBC) patients with uncertainty surrounding the factors and patterns that are contributing.We obtained characteristics and survival data from 206,156 YBC patients...

Pharmacological Management of IgG4-Related Disease: From Traditional to Mechanism-Based Targeted Therapies.

Jan 6, 2025

IgG4-related disease (IgG4-RD) is an immune-mediated disorder characterized by organ enlargement and dysfunction. The formation of tertiary lymphoid tissues (TLTs) in affected organs is crucial for understanding IgG4-RD, as T...

The implication of pericardial effusion in the third trimester for preeclampsia and heart failure in high-risk pregnant women.

Jan 6, 2025

With the growing number of high-risk pregnant women, echocardiography frequently reveals pericardial effusion (PE). However, the clinical implications of PE are unknown.We analyzed a cohort of 406 high-risk pregnant women who...

Genetic predisposition of metabolic dysfunction-associated steatotic liver disease: a population-based genome-wide association study.

Jan 6, 2025

Although metabolic dysfunction-associated steatotic liver disease (MASLD) has been proposed to replace the diagnosis of non-alcoholic fatty liver disease (NAFLD) with new diagnostic criteria since 2023, the genetic...

Should combined MTX and CoQ10 use be reconsidered in terms of steatosis? A biochemical, flow cytometry, histopathological experimental study.

Dec 30, 2024

In the present study, the effects of coenzyme Q10 (CoQ10), which is widely used in daily life, on the methotrexate (MTX)-induced hepatotoxicity, which is widely used today in malignancies and autoimmune diseases, were examined....

Younger age as an independent factor for second primary head and neck cancer in esophageal squamous cell carcinoma patients after curative esophagectomy: A two-center retrospective study.

Dec 30, 2024

Postoperative survival of esophageal cancer patients has improved with advances in technology and treatment modalities. However, squamous cell carcinoma (SCC) often affects the esophagus together with the head and neck regions,...

Palliative endoscopic treatment of malignant central airway obstruction.

Dec 30, 2024

To examine the outcome of palliative endoscopic treatment of malignant central airway obstruction (CAO) and identify predictors for Days Alive and Out of Hospital (DAOH), overall survival and treatment related...

Comparing combined paravaginal repair with pubocervical fascia plication versus standard anterior colporrhaphy for the treatment of stress urinary incontinence in women with anterior vaginal wall prolapse: a randomised controlled trial.

Dec 30, 2024

Stress urinary incontinence (SUI) is prevalent among women, often occurring alongside anterior vaginal wall prolapse. This study compares the efficacy and safety of an improved vaginal wall repair technique with pubocervical...

Unsupervised clustering analysis of treatment strategies for elite female athletes with severe stress urinary incontinence: focusing on competition return and SUI improvement.

Dec 30, 2024

To evaluate two primary outcomes in elite female athletes (EFAs) with severe stress urinary incontinence (SUI) 24 months post-intervention: return to elite-level competition and improvement in SUI symptoms. Clustering analysis...

Pediatric Neurosonography: Comprehensive Review and Systematic Approach.

Dec 30, 2024

Neurosonography (NSG) is pivotal for rapid, point-of-care neonatal brain assessment. This review elucidates the comprehensive applications of NSG in pediatric care, emphasizing its role in early diagnosis and management of...

The effect of light therapy on insomnia: A systematic review and meta-analysis.

Dec 30, 2024

Light is a crucial factor influencing sleep arousal patterns. This meta-analysis investigates the efficacy of light therapy (LT) for insomnia treatment.Five electronic databases were independently searched by two reviewers until...

Long-Term Self-Administered Outpatient Parenteral Antimicrobial Therapy in the Treatment of Tuberculosis.

Dec 30, 2024

To investigate the safety profiles and clinical outcomes in a continuous cohort of tuberculosis (TB) patients from a clinical referral centre in Germany receiving self-administered outpatient parenteral antimicrobial therapy...

Perceptions on circumcision for HIV prevention: an application of the health belief model in a qualitative enquiry among young men in Eswatini.

Dec 30, 2024

Voluntary medical male circumcision (VMMC) was identified as an effective strategy in HIV prevention. Although circumcision reduces heterosexual acquisition of HIV by 60%, there is low uptake of VMMC services in Eswatini. This...

Effects of alpha-1 adrenergic receptor blockers on erectile function: a systematic review.

Dec 23, 2024

Alpha-1 adrenergic receptor antagonist (α1-ARA) are well established treatment for benign prostatic hyperplasia (BPH)-associated lower urinary tract symptoms (LUTS). Since BPH and erectile dysfunction (ED) are commonly...

Examining Mental Health Changes Before and After Rhinoplasty: An Analytical Study.

Dec 23, 2024

This study aimed to explore the mental health status of individuals seeking rhinoplasty before and 3 months after surgery. This study was conducted in 2022 at Velayat Hospital, involving patients aged 18-60 who were seeking...

Comparison of patient radiation exposure and procedure time between CT-fluoroscopy and spiral CT for lumbar epidural steroid injections.

Dec 23, 2024

To compare patient radiation exposure and procedure time for lumbar epidural steroid injections (ESIs) performed under CT-fluoroscopy (CTF) vs spiral CT-guidance.A retrospective cohort study of 767 consecutive lumbar ESIs...

Working memory processes and the histamine-3 receptor in schizophrenia: a [C]MK-8278 PET-fMRI study.

Dec 23, 2024

Working memory impairment is a prominent feature of schizophrenia which predicts clinical and functional outcomes. Preclinical data suggest histamine-3 receptor (H3R) expression in cortical pyramidal neurons may have a role in...

Are ADHD trajectories shaped by the social environment? A longitudinal study of maternal influences on the preschool origins of delay aversion.

Dec 23, 2024

Attention-deficit/hyperactivity disorder (ADHD) is commonly attributed to neuro-cognitive deficits of genetic and/or prenatal/perinatal environmental origins. Sonuga-Barke proposed an alternative formulation, suggesting that...

Follow Us

PubMed