PubMed

Efficacy of navigation system-assisted distraction osteogenesis for hemifacial microsomia based on artificial intelligence for 3 to 18 years old: study protocol for a randomized controlled single-blind trial.

Jan 15, 2024

Mandibular distraction osteogenesis (MDO) is a major part of the treatment for hemifacial microsomia patients. Due to the narrow surgical field of the intraoral approach, osteotomy accuracy is highly dependent on the...

Factors influencing the selection criteria of Saudi board orthopedic surgery applicants: a national survey of program directors.

Jan 15, 2024

Annually, medical students vie to secure a seat with an orthopedic residency program. This rigorous competition places orthopedic surgery as one of the most competitive specialties in the medical field. Although several...

Platelet-rich plasma in orthopedics: Bridging innovation and clinical applications for bone repair.

Jan 15, 2024

In the burgeoning domain of orthopedic therapeutic research, Platelet-Rich Plasma (PRP) has firmly established its position, transforming paradigms ranging from tissue regeneration to the management of chondral lesions. This...

The Scope and Distribution of Upper Extremity Nerve Injuries Associated With Combat-Related Extremity Limb Salvage.

Jan 15, 2024

Chronic pain and functional limitations secondary to nerve injuries are a major barrier to optimal recovery for patients following high-energy extremity trauma. Given the associated skeletal and soft tissue management challenges...

The PAncreatic Surgery Composite Endpoint PACE – Development and Validation of a Clinically Relevant Endpoint Requiring Lower Sample Sizes.

Jan 15, 2024

To provide a composite endpoint in pancreatic surgery.Single endpoints in prospective and randomized studies have become impractical due to their low frequency and the marginal benefit of new interventions.Data from prospective...

Current trends and outcomes for unilateral groin hernia repairs in the United States using the Abdominal Core Health Quality Collaborative database: A multicenter propensity score matching analysis of 30-day and 1-year outcomes.

Jan 15, 2024

Different unilateral groin hernia repair approaches have been developed in the last 2 decades. The most commonly done approaches are open inguinal hernia repair by the Lichenstein technique, laparoscopic approach by either total...

Risk factors of cognitive impairment in elderly people in the Republic of Kazakhstan.

Jan 15, 2024

To study the risk factors of cognitive impairment in elderly people in the Republic of Kazakhstan.Study design – cross – sectional. 385 elderly people randomly selected from all over Kazakhstan took part in the...

Lung injuries induced by ozone exposure in female mice: Potential roles of the gut and lung microbes.

Jan 15, 2024

Ozone (O) is one of the most harmful pollutants affecting health. However, the potential effects of O exposure on microbes in the gut-lung axis related to lung injuries remain elusive. In this study, female mice were exposed to...

Elexacaftor/tezacaftor/ivacaftor improves chronic rhinosinusitis detected by magnetic resonance imaging in children with cystic fibrosis on long-term therapy with lumacaftor/ivacaftor.

Jan 15, 2024

Previous studies using magnetic resonance imaging (MRI) demonstrated early onset and progression of chronic rhinosinusitis (CRS) from infancy to school age, and response to lumacaftor/ivacaftor (LUM/IVA) therapy in children with...

Comorbidity of Dementia: A Cross-Sectional Study of PUMCH Dementia Cohort.

Jan 15, 2024

Comorbidities reduce quality of life for people with dementia and caregivers. Some comorbidities share a genetic basis with dementia.The objective of this study is to assess comorbidity in patients with different dementia...

Influence of TMX2-CTNND1 polymorphism on cortical thickness in schizophrenia and their unaffected sibling: an exploratory study based on target region sequencing.

Jan 15, 2024

The advancement of neuroimaging and genetic research has revealed the presence of morphological abnormalities and numerous risk genes, along with their associations.The cortical thickness of 129 schizophrenia patients, 42...

Serum neurofilament light as a potential marker of illness duration in bipolar disorder.

Jan 15, 2024

Investigation on specific biomarkers for diagnostic or prognostic usage in mental diseases and especially bipolar disorder BD seems to be one outstanding field in current research. Serum neurofilament light (sNfL), a marker for...

Biomarkers of bipolar disorder based on metabolomics: A systematic review.

Jan 15, 2024

Bipolar disorder (BD) is a severe affective disorder characterized by recurrent episodes of depression or mania/hypomania, which significantly impair cognitive function, life skills, and social abilities of patients. There is...

Comparison of brexpiprazole, aripiprazole, and placebo for Japanese major depressive disorder: A systematic review and network meta-analysis.

Jan 15, 2024

This systematic review and frequentist network meta-analysis used random-effects models is conducted to determine whether there are differences in the efficacy, acceptability, tolerability, and safety profiles of brexpiprazole...

Enhancing drug checking services for supply monitoring: perspectives on implementation in syringe service programs in the USA.

Jan 15, 2024

Shifts in the US drug supply, including the proliferation of synthetic opioids and emergence of xylazine, have contributed to the worsening toll of the overdose epidemic. Drug checking services offer a critical intervention to...

A Systematic Evaluation of Machine Learning-Based Biomarkers for Major Depressive Disorder.

Jan 15, 2024

Biological psychiatry aims to understand mental disorders in terms of altered neurobiological pathways. However, for one of the most prevalent and disabling mental disorders, major depressive disorder (MDD), no informative...

Mapping the Lobbying Footprint of Harmful Industries: 23 Years of Data From OpenSecrets.

Jan 15, 2024

Policy Points Our research reveals the similarities and differences among the lobbying activities of tobacco, alcohol, gambling, and ultraprocessed food industries, which are often a barrier to the implementation of public...

Combating ageism in medical education with narrative medicine.

Jan 15, 2024

Ageism is common in medical trainees and difficult to overcome. The My Life, My Story program has been shown to be an effective tool for increasing empathy. We explored its use as an instrument for combating ageism by...

Comparing the effects of trunk stabilisation and activation exercises on pain and disability in postpartum lumbo-pelvic pain: A randomised controlled trial.

Jan 15, 2024

The purpose of this study was to determine and compare the effects of trunk stabilisation and activation exercises on pain and disability in postpartum lumbo-pelvic pain. It was a randomised clinical trial (ClinicalTrials.gov:...

Lung function changes in children exposed to mine fire smoke in infancy.

Jan 15, 2024

Chronic, low-intensity air pollution exposure has been consistently associated with reduced lung function throughout childhood. However, there is limited research regarding the implications of acute, high-intensity air pollution...

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