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Placentas associated with female neonates from pregnancies complicated by urinary-tract infections have higher cAMP content and cytokines expression than males.

Apr 29, 2021

The cAMP pathway is involved in important biological processes including immune regulation and...

Screening for idiopathic normal pressure hydrocephalus in the elderly after falls.

Apr 29, 2021

Many patients with idiopathic normal pressure hydrocephalus (iNPH) have reportedly fallen prior to...

Reproductive Health Care for Incarcerated Pregnant, Postpartum, and Nonpregnant Individuals.

Apr 29, 2021

Obstetrician-gynecologists and other women’s health care practitioners can support efforts...

PAX8 and MECOM are interaction partners driving ovarian cancer.

Apr 29, 2021

The transcription factor PAX8 is critical for the development of the thyroid and urogenital...

IGF-1R anti-idiotypic antibody antagonist exhibited anti-ovarian cancer bioactivity and reduced cisplatin resistance.

Apr 29, 2021

Ovarian cancer is the most deadly gynecological malignant tumor in the world today. Previous...

Development of a high payload, cancer-targeting liposomes of methyl aminolevulinate for intraoperative photodynamic diagnosis/therapy of peritoneal carcinomatosis.

Apr 29, 2021

Methyl aminolevulinate (MAL) is a photosensitizer topically used for photodynamic diagnosis (PDD)...

A High-Androgen Microenvironment Inhibits Granulosa Cell Proliferation and Alters Cell Identity.

Apr 29, 2021

A naturally occurring bovine model with excess follicular fluid androstenedione (High A4), reduced...

Prediction of severe neutropenia and diarrhoea in breast cancer patients treated with abemaciclib.

Apr 29, 2021

Neutropenia and diarrhoea are common and potentially serious adverse events associated with...

Preparation, characterization, and in vitro tumor-suppressive effect of anti-miR-21-equipped RNA nanoparticles.

Apr 29, 2021

MicroRNAs play an irreplaceable role in gene expression regulation. Upregulation of several miRNAs...

Effect of an educational intervention on women’s healthcare provider knowledge gaps about breast density, breast cancer risk, and screening.

Apr 29, 2021

We sought to assess the effect of an educational intervention, based on DenseBreast-info.org...

Preeclampsia May Precede Later-Life Stroke in Some Women

Apr 28, 2021

Those with history of pregnancy complication had a more than three-fold higher risk of...

Kidney intercalated cells are phagocytic and acidify internalized uropathogenic Escherichia coli.

Apr 26, 2021

Kidney intercalated cells are involved in acid-base homeostasis via vacuolar ATPase expression....

Tamsulosin Versus Placebo to Prevent Postoperative Urinary Retention Following Female Pelvic Reconstructive Surgery: a Multicenter Randomized Controlled Trial.

Apr 26, 2021

Postoperative urinary retention is common following female pelvic reconstructive surgery. Alpha...

Preconceptional and the first trimester exposure to PM and offspring neurodevelopment at 24 months of age: Examining mediation by maternal thyroid hormones in a birth cohort study.

Apr 26, 2021

Prenatal fine particulate matter (PM) exposure has been associated with impaired offspring...

A Population Pharmacokinetic Meta-analysis of Veliparib, a PARP Inhibitor, Across Phase I/II/III Trials in Cancer Patients.

Apr 26, 2021

Veliparib (ABT-888) is a poly (ADP-ribose) polymerase (PARP) inhibitor in development for...

Oleuropein reduces cisplatin resistance in ovarian cancer by targeting apoptotic pathway regulators.

Apr 26, 2021

Despite many attempts to treat ovarian cancer, 13,940 individuals perish annually due to this...

Circular RNA circE2F2 promotes malignant progression of ovarian cancer cells by upregulating the expression of E2F2 protein via binding to HuR protein.

Apr 26, 2021

Ovarian cancer (OC) is a gynecological malignancy with a poor prognosis and low survival rate....

Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu.

Apr 26, 2021

An increased number of highly active regulatory T cells (Tregs) and macrophages has been found in...

A homozygous variant in TBPL2 was identified in women with oocyte maturation defects and infertility.

Apr 26, 2021

What are the genetic causes of oocyte maturation defects?A homozygous splicing variant...

Design, synthesis and molecular docking studies of thymol based 1,2,3-triazole hybrids as thymidylate synthase inhibitors and apoptosis inducers against breast cancer cells.

Apr 26, 2021

Natural product produced by plants has been the backbone for numerous anticancer agents. In the...

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