LRRK2 inhibition potentiates PARP inhibitor cytotoxicity through inhibiting homologous recombination-mediated DNA double strand break repair.
PARP inhibitors induce DNA lesions, the repair of which are highly dependent on homologous...
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PARP inhibitors induce DNA lesions, the repair of which are highly dependent on homologous...
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Synthetic lethality is a successful strategy employed to develop selective chemotherapeutics...
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To evaluate risk factors leading to non-alcoholic fatty liver disease (NAFLD) occurrence in...
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Effective and efficient participant recruitment is a key determinant of the success of a research...
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Novel series of diphenyl-1H-pyrazoles (4a-g) and pyrazolo[3,4-b]pyridines (5a-g and 7a-i) were...
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Considering the complementarity of mammography and breast MRI, the research of feature fusion...
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To evaluate the number of patients with early-stage breast cancer who could benefit from the...
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Previous study indicated that Ulinastatin (UTI) increased glutamine uptake by upregulation of...
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To assess feasibility, safety and risk factors for failure associated with out-patient surgery for...
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In myasthenia gravis (MG), first-line treatment for MG is acetylcholinesterase inhibitors which...
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Despite a long history of maternal health programs, the quality of obstetric care and access to...
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To determine whether preimplantation genetic testing (PGT) is associated with an increase in...
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Ovarian cancer is a lethal gynecological malignancy. Long non-coding RNA antisense non-coding RNA...
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Laparoscopy is indicated in many patients with abdominal and pelvic malignancy. If cancer cells...
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We discovered 6-substituted thieno[2,3-d]pyrimidine compounds (3-9) with 3-4 bridge carbons and...
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The emergence of the novel coronavirus infection that arose in Wuhan, China in December 2019 has...
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The present study aimed to explore the associations between the expression pattern of molecules in...
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To compare the performance of imaging interpretation, intra- and inter-reader agreement between an...
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The combination of a taxane with trastuzumab and pertuzumab is standard of care for first-line...
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This study aimed to determine the optimal β value of the relaxation control parameter and the...
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