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OB/GYN General

The first copper(ii) complex with 1,10-phenanthroline and salubrinal with interesting biochemical properties.

Apr 28, 2020

The novel copper complex [Cu(phen)2(salubrinal)](ClO4)2 (C0SAL) has been synthesised and characterised. Copper(ii) is coordinated by salubrinal through the thionic group, as shown by the UV-Vis, IR, E...

The generally low sensitivity of CA 125 for FIGO stage I ovarian cancer diagnosis increases for endometrioid histotype.

Apr 28, 2020

The serum marker CA 125 is still the most widely used biomarker for ovarian cancer (OC) diagnosis in gynecological and oncological setting, but its predictive role in early-stage OC is still debated. ...

Filopodia play an important role in the trans-mesothelial migration of ovarian cancer cells.

Apr 28, 2020

Ovarian cancer cells shed from primary tumors can spread easily to the peritoneum via the peritoneal fluid. To allow further metastasis, the cancer cells must interact with the mesothelial cell layer,...

Greater Influence of Aerobic Fitness on Autonomic Support of Blood Pressure in Young Women Than in Older Women.

Apr 28, 2020

Aging increases autonomic support of blood pressure; however, the impact of aerobic fitness on autonomic support of blood pressure has not been addressed in women. As such, we hypothesized that aerobi...

Merr isoflavone gel improves vaginal vascularization in postmenopausal women.

Apr 28, 2020

This study aimed to analyze the effects of isoflavones from Merr (soy) used topically as a vaginal gel on the induction of vascularization of the vaginal tissue in postmenopausal women. A placebo-co...

Co-occurring medical conditions in adults with Down syndrome: A systematic review toward the development of health care guidelines. Part II.

Apr 28, 2020

Adults with Down syndrome (DS) represent a unique population who are in need of clinical guidelines to address their medical care. Many of these conditions are of public health importance with the pot...

The effect of rapamycin on bovine oocyte maturation success and metaphase telomere length maintenance.

Apr 28, 2020

Maternal aging-associated reduction of oocyte viability is a common feature in mammals, but more research is needed to counteract this process. In women, the first aging phenotype appears with a decli...

Novel approach for pathogenesis of osteoporosis in ovariectomized rats as a model of postmenopausal osteoporosis.

Apr 28, 2020

Obesity and osteoporosis are two chronic conditions that have been increasing in prevalence. Menopausal transition years place women at high risk for visceral obesity as well as osteoporosis. This stu...

Bowel and ureteral assessment by indocyanine green real-time visualization during deep infiltrating endometriosis surgery - Video vignette.

Apr 28, 2020

To report the utility of intraoperative use of indocyanine green (ICG) during deep infiltrating endometriosis (DIE) laparoscopic surgery for intestinal and ureteral assessment.A video on the use of IC...

The role of serum osteoprotegerin level in diagnosis of disease and determining cardiovascular risk of polycystic ovary syndrome.

Apr 28, 2020

Although animal studies claim that osteoprotegerin (OPG) is preventive on this system, there are conflicting results in human studies. The aim of this study was to investigate the role of OPG in the ...

Stress, stigma, violence experiences and social support of us infertile women.

Apr 28, 2020

: Previous studies investigated the physical, psychological and sociological effects of infertility; however, stigma and violence experiences of infertile women haven't yet been studied in the US. The...

APPL1 as an important regulator of insulin and adiponectin signaling pathways in the PCOS: A narrative review.

Apr 28, 2020

Adaptor protein containing a PH domain, PTB domain and leucine zipper motif 1 (APPL1) plays a central role as the main contributing factor in the adiponectin and insulin signaling. This review aims to...

Laparoscopic ablation or excision with helium thermal coagulator versus electrodiathermy for the treatment of mild-to-moderate endometriosis: randomized controlled trial.

Apr 28, 2020

To compare electrodiathermy with helium thermal coagulation in laparoscopic treatment of mild-to-moderate endometriosis.Parallel-group randomized controlled trial.A UK endometriosis centre.Non-pregnan...

BRD4 inhibition suppresses PD-L1 expression in triple-negative breast cancer.

Apr 28, 2020

Programmed death-ligand 1 (PD-L1) expression on the surface of tumour cells can cause tumour immune evasion. Benefits of combining anti-PD-L1 therapy with nab-paclitaxel in patients with advanced trip...

Breast Tumor Microenvironment: Emerging target of therapeutic phytochemicals.

Apr 28, 2020

Triple negative breast cancer (TNBC) is the most aggressive and challenging form of breast cancers. Tumor microenvironment (TME) of TNBC is associated with induction of metastasis, immune system suppr...

State or trait? Measuring resilience by generalisability theory in breast cancer.

Apr 28, 2020

Whether resilience should be conceptualised as a state or trait is debated. The precise distinction between state versus trait aspects of resilience can help identify dynamic targets for resilience-ba...

Can second-look ultrasound downgrade MRI-detected lesions? A retrospective study.

Apr 28, 2020

To determine whether MRI-detected suspicious (BIRADS 4 & 5) breast lesions can be downgraded using second-look ultrasound (SLU) and thus reduce unnecessarily performed breast biopsies.A retrospective ...

Real-World Data of Pyrotinib-Based Therapy in Metastatic HER2-Positive Breast Cancer: Promising Efficacy in Lapatinib-Treated Patients and in Brain Metastasis.

Apr 28, 2020

Pyrotinib is a newly-developed irreversible pan-ErbB receptor tyrosine kinase inhibitor. This study reported the first real-world data of pyrotinib-based therapy in metastatic human epidermal growth f...

OB/GYN Providers' Knowledge of Racial and Ethnic Reproductive Health Disparities.

Apr 28, 2020

This study explores OB/GYN providers' knowledge about published health and healthcare disparities in women's reproductive health.We collected demographic and health disparities knowledge information f...

Thiazolidinediones reduce the risk of hepatocellular carcinoma and hepatic events in diabetic patients with chronic hepatitis B.

Apr 28, 2020

Thiazolidinediones (TZDs) improve glycaemic control, and ameliorate liver steatosis, inflammation, and fibrosis in patients with fatty liver disease. We aimed to study the impact of TZD and glycaemic ...

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