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OB/GYN General

Hyperglucosuria Induced by Dapagliflozin Augments Bacterial Colonization in the Murine Urinary Tract.

Apr 22, 2020

Diabetes is a leading risk factor for development of urinary tract infection (UTI). UTI caused by uropathogenic Escherichia coli (UPEC), and other uropathogens is a common infectious condition affecti...

Same-Day Discharge and Quality of Life for Primary Laparoscopic Rectopexy for Rectal Prolapse in Children: A 10-Year Experience.

Apr 22, 2020

Rectal prolapse (RP) in pediatric patients may require surgical intervention. Varying surgical approaches and heterogenous patient populations have resulted in difficulty defining surgical outcomes a...

Hepatitis B virus seroepidemiology data for Africa: Modelling intervention strategies based on a systematic review and meta-analysis.

Apr 22, 2020

International Sustainable Development Goals (SDGs) for elimination of hepatitis B virus (HBV) infection set ambitious targets for 2030. In African populations, infant immunisation has been fundamental...

Prognostic significance of neutrophil-to-lymphocyte ratio in HPV status era for oropharyngeal cancer.

Apr 22, 2020

To evaluate the role of baseline neutrophil-to-lymphocyte ratio (NLR) as prognostic marker in squamous cell carcinoma of the oropharynx (OPC) treated with definitive chemo-radiotherapy (CRT) in the er...

Prevalence, incidence and associated factors for HBV infection among male and female prisoners in Central Brazil: a multicenter study.

Apr 22, 2020

Prison population are at high risk for hepatitis B virus (HBV) infection. The aim of this study was to assess the prevalence, incidence, HBV associated factors and the circulating genotypes/subtypes.A...

Compliance with international guidelines in adults with encephalitis.

Apr 22, 2020

Encephalitis is associated with significant neurological disability and mortality. Many guidelines are published for encephalitis management but compliance with them is unknown.To evaluate the appropr...

Improving immunogenicity and safety of flagellin as vaccine carrier by high-density display on virus-like particle surface.

Apr 22, 2020

Flagellin is a protein-based adjuvant that activates toll-like receptor (TLR) 5. Flagellin has been actively explored as vaccine adjuvants and carriers. Preclinical and clinical studies find flagellin...

Reproduction and Pregnancy in Inflammatory Bowel Disease - Management and Treatment Based on Current Guidelines.

Apr 22, 2020

Inflammatory bowel diseases (IBD) affect mainly young population. Therefore, fertility and pregnancy are important clinical issues to be considered. Generally, fertility in IBD patients is not decreas...

The role of maternal methylation in the association between prenatal meteorological conditions and neonatal H19/H19-DMR methylation.

Apr 22, 2020

Meteorological conditions during pregnancy can affect birth outcome, which has been linked to the H19/H19-differentially methylated region (DMR). However, the detailed mechanisms underlying this assoc...

Effects of expressive writing intervention for women's PTSD, depression, anxiety and stress related to pregnancy: A meta-analysis of randomized controlled trials.

Apr 22, 2020

Expressive writing (EW) is a common psychological intervention that aims to improve the mental health of traumatized individuals. Pregnancy is considered an anxious or traumatic experience for some wo...

Maternal Undernourishment in Guinea Pigs Leads to Fetal Growth Restriction with Increased Hypoxic Cells and Oxidative Stress in the Brain.

Apr 22, 2020

We determined whether maternal nutrient restriction (MNR) in guinea pigs leading to fetal growth restriction (FGR) impacts markers for brain hypoxia and oxidative stress.Guinea pigs were fed ad libitu...

[Out-of-Hospital Cardiopulmonary Resuscitation].

Apr 22, 2020

With an incidence of 50 - 70 resuscitations attempted per 100000 inhabitants and year Out-of-hospital cardiac arrest (OHCA) is one of the leading causes of death in adults in the developed world. ...

Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C.

Apr 22, 2020

A central and unique aspect of high-grade serous ovarian carcinoma (HGSC) is the extensive transcoelomic spreading of tumor cell via the peritoneal fluid or malignant ascites. We and others identified...

Inhibition of collagen XI alpha 1-induced fatty acid oxidation triggers apoptotic cell death in cisplatin-resistant ovarian cancer.

Apr 22, 2020

Collagen type XI alpha 1 (COL11A1) is a novel biomarker associated with cisplatin resistance in ovarian cancer. However, the mechanisms underlying how COL11A1 confers cisplatin resistance in ovarian c...

Inhibition of the Wnt/β-catenin pathway enhances antitumor immunity in ovarian cancer.

Apr 22, 2020

The Wnt/β-catenin pathway is linked to tumorigenesis in a variety of tumors and promotes T cell exclusion and resistance to checkpoint inhibitors. We sought to determine whether a small molecule inhi...

Population Screening for Inherited Predisposition to Breast and Ovarian Cancer.

Apr 22, 2020

The discovery of genes underlying inherited predisposition to breast and ovarian cancer has revolutionized the ability to identify women at high risk for these diseases before they become affected. Wo...

Design of Fluorophore Loaded Human Serum Albumin Nanoparticles for Specific Targeting of NIH:OVCAR3 Ovarian Cancer Cells.

Apr 22, 2020

Nowadays, extensive research is carried out into finding innovative solutions for the development of stable, reproductible and highly efficient fluorescent contrast agents having the ability of target...

Circulating plasma metabolites and risk of rheumatoid arthritis in the Nurses' Health Study.

Apr 22, 2020

RA develops slowly over years. We tested for metabolic changes prior to RA onset using a large non-targeted metabolomics platform to identify novel pathways and advance understanding of RA development...

Fluorescence and Multiphoton Imaging for Tissue Characterization of a Model of Postmenopausal Ovarian Cancer.

Apr 22, 2020

To determine the efficacy of targeted fluorescent biomarkers and multiphoton imaging to characterize early changes in ovarian tissue with the onset of cancer.A transgenic TgMISIIR-TAg mouse was used a...

17β-Estradiol improves insulin signalling and insulin resistance in the aged female hearts: Role of inflammatory and anti-inflammatory cytokines.

Apr 22, 2020

Aging effects in energy balance in all tissues and organs, including the cardiovascular. The risk of cardiovascular disease is drastically higher in postmenopausal women than in premenopausal women. E...

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