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OB/GYN General

Multi-modal immune phenotyping of maternal peripheral blood in normal human pregnancy.

Mar 13, 2020

Changes in maternal immunity during pregnancy can result in an altered immune state and, as a natural perturbation, this provides an opportunity to understand functional interactions of the immune sys...

Common genetic variants in ADCY5 and gestational glycemic traits.

Mar 13, 2020

Two meta-analysis of genome wide association studies identified two variants at adenylate cyclase 5 (ADCY5) associated with type 2 diabetes mellitus, fasting and 2-hour glucose in non-pregnant individ...

Potential new tool for anemia screening: An evaluation of the performance and usability of the TrueHb Hemometer.

Mar 13, 2020

In low- and middle-income countries, many women experience anemia during pregnancy due to insufficient dietary intake of key micronutrients, parasitic infections, hemoglobinopathies, and chronic infec...

'Supporting a first-time mother': Assessment of success of a breastfeeding promotion programme.

Mar 13, 2020

The aim of this study was to measure the effectiveness on breast feeding rates by the program 'Supporting a First-time Mother', a web-based platform of interactionbetween first-time mothers and breast...

GeneReader NGS System Is a Useful Sequencing Platform for Clinical Testing of and .

Mar 13, 2020

Although next-generation sequencing (NGS) is widely used for sequencing analysis, it involves a fragmented workflow along with complex bioinformatic analysis and interpretation. In this study, the pe...

Parity as a Prognostic Factor in Patients with Advanced-Stage Epithelial Ovarian Cancer.

Mar 13, 2020

This study aimed to determine the prognostic factors influencing the overall survival (OS) of Iranian women with epithelial ovarian cancer (EOC).Information about newly diagnosed patients with confirm...

Tumor-derived exosomes in the regulation of macrophage polarization.

Mar 13, 2020

This review focuses on exosomes derived from various cancer cells. The review discusses the possibility of differentiating macrophages in alternatively activated anti-inflammatory pro-tumorigenic M2 m...

Association of Germline Variant Status With Therapy Response in High-risk Early-Stage Breast Cancer: A Secondary Analysis of the GeparOcto Randomized Clinical Trial.

Mar 13, 2020

The GeparOcto randomized clinical trial compared the efficacy of 2 neoadjuvant breast cancer (BC) treatment regimens: sequential intense dose-dense epirubicin, paclitaxel, and cyclophosphamide (iddEPC...

Long non-coding RNA RHPN1-AS1 promotes tumorigenesis and metastasis of ovarian cancer by acting as a ceRNA against miR-596 and upregulating LETM1.

Mar 13, 2020

In recent decades, long non-coding RNAs (lncRNAs) have been reported as crucial functional regulators involved in ovarian cancer. In the present study, we explored how lncRNA RHPN1-AS1 influences the ...

ICSI does not improve reproductive outcomes in autologous ovarian response cycles with non-male factor subfertility.

Mar 13, 2020

Does the method of fertilisation improve reproductive outcomes in poor ovarian response (POR) cycles when compared to all other ovarian response categories in the absence of male factor subfertility?I...

Rectal disc resection improves stool frequency in patients with deep infiltrating endometriosis: A prospective study.

Mar 13, 2020

Gastrointestinal symptoms occur with deeply infiltrating endometriosis (DIE) of the rectum.To explore the medium-term gastrointestinal functional outcomes after rectal disc resection for endometriosis...

The effect of type of oral contraceptive pill and duration of use on fresh and cumulative live birth rates in IVF/ICSI cycles.

Mar 13, 2020

Are there any differences in the fresh (LB) and cumulative live birth rates (CLBR) of women undergoing controlled ovarian stimulation (COS) for IVF/ICSI following pretreatment with different types of ...

Body Mass Index and Polycystic Ovary Syndrome: A Two-sample Bidirectional Mendelian Randomization Study.

Mar 13, 2020

Observational studies have shown a link between elevated body mass index (BMI) and the risk of polycystic ovary syndrome (PCOS). While Mendelian randomization (MR) studies in Europeans have suggested ...

The therapeutic effect of interleukin-22 in high androgen-induced polycystic ovary syndrome.

Mar 13, 2020

Polycystic ovary syndrome (PCOS) is a complex syndrome involving both endocrine and metabolic disorders. Gut microbiota and the intestinal immune factor IL-22 play an important role in the pathogenesi...

Feasibility of abbreviated magnetic resonance imaging (AB-MRI) screening in women with a personal history (PH) of breast cancer.

Mar 13, 2020

To investigate the feasibility of abbreviated magnetic resonance imaging (AB-MRI) in women with a personal history (PH) of breast cancer as a screening tool.We retrospectively reviewed 1880 screening ...

Total, renal and hepatic clearances of doxorubicin and formation clearance of doxorubicinol in patients with breast cancer: Estimation of doxorubicin hepatic extraction ratio.

Mar 13, 2020

Doxorubicin (DOX) is a cytotoxic drug which has remained as an essential component of chemotherapy regiment for breast cancer. The cardiotoxicity of DOX is related to the accumulation of its main meta...

Correlation of clinicopathological features and LRG5 expression in triple-negative breast carcinoma.

Mar 13, 2020

LGR5 is the most robust known stem cell marker for gastrointestinal tumors, but there are few reports in breast cancer. Triple negative breast cancer (TNBC) is the most malignant subtype of breast can...

Associations of polymorphisms in interleukins with susceptibility to breast cancer: Evidence from a meta-analysis.

Mar 13, 2020

Associations between polymorphisms in interleukins and breast cancer (BC) were already investigated by many studies, yet with controversial findings. The aim of this meta-analysis was to better clarif...

Inferences of Individual Drug Response-Related Long Non-coding RNAs Based on Integrating Multi-omics Data in Breast Cancer.

Mar 13, 2020

Differences in individual drug responses are obstacles in breast cancer (BRCA) treatment, so predicting responses would help to plan treatment strategies. The accumulation of cancer molecular profilin...

Affective Symptoms and Health-Related Quality of Life Among Women with Stress Urinary Incontinence: Cross-Sectional Study.

Mar 12, 2020

To evaluate the relationship between affective symptoms, clinical variables of uro-gynaecological history and health-related quality of life (QoL) among women with stress urinary incontinence (SUI) in...

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