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OB/GYN General

Perineal Laceration and Episiotomy Repair Using a Beef Tongue Model.

Mar 19, 2020

Declining rates of operative vaginal deliveries and routine episiotomy in obstetric practice, along with rising cesarean section rates, have decreased OB/GYN resident experience with episiotomy repair...

Cost and Reimbursement of Providing Routine Vaccines in Outpatient Obstetrician/Gynecologist Settings.

Mar 19, 2020

We sought to determine the costs and reimbursement associated with running a vaccine program in five obstetrics/gynecology (Ob/Gyn) practices in Colorado that had participated in a 3-year randomized, ...

Efficacy and Safety of Remogliflozin Etabonate, a New Sodium Glucose Co-Transporter-2 Inhibitor, in Patients with Type 2 Diabetes Mellitus: A 24-Week, Randomized, Double-Blind, Active-Controlled Trial.

Mar 13, 2020

Metformin is the first-line treatment for type 2 diabetes mellitus (T2DM), but many patients either cannot tolerate it or cannot achieve glycemic control with metformin alone, so treatment with other ...

Adenovirus infection among pediatric patients with cancer and in pediatric recipients of hematopoietic stem cell: a multicenter nationwide study.

Mar 13, 2020

The aim was to evaluate the incidence, clinical course and outcome of adenoviral infection (AdVI) in pediatric patients diagnosed and treated due to cancer and in pediatric recipients of hematopoietic...

Promoting and maintaining urinary continence: Follow-up from a cluster-randomized trial of elderly village women in Bangladesh.

Mar 13, 2020

Pelvic floor and mobility exercises were shown to be effective in managing incontinence in a cluster-randomized trial (CRT) of village women aged 60 to 75 years in Bangladesh. The present analysis exa...

Diagnostic Accuracy of the Mean Platelet Volume in the Prediction of Upper Urinary Tract Infections.

Mar 13, 2020

The studies have reported that mean platelet volume may be a marker in the discrimination of upper and lower urinary tract infections. We investigated whether the mean platelet volume was a reliable i...

Relationship between desire to void and bladder capacity and rectal sensory function in patients with multiple sclerosis and anorectal disorders.

Mar 13, 2020

The primary aim of this study was to assess the relationship between a strong desire to void (SDV) and rectal sensory function in patients with multiple sclerosis (PwMS) and anorectal disorders. The s...

Diminished hepatic IFN response following HCV clearance triggers HBV reactivation in coinfection.

Mar 13, 2020

In patients with HBV and HCV coinfection, HBV reactivation leading to severe hepatitis has been reported with the use of direct-acting antivirals (DAAs) to treat HCV infection. Here we study the molec...

Real world clinical practice in treating advanced hepatocellular carcinoma: When East meets West.

Mar 13, 2020

The Barcelona Clinic Liver Cancer (BCLC) stage C (BCLC C) of hepatocellular carcinoma (HCC) includes a heterogeneous population for which sorafeninb is one of the recommended therapies. We aim to eval...

De-intensification of therapy in human papillomavirus associated oropharyngeal cancer: A systematic review of prospective trials.

Mar 13, 2020

Numerous trials have been launched over the prior decade examining the safety and efficacy of therapy de-escalation in human papillomavirus (HPV)-associated oropharyngeal cancer (OPC). Because no summ...

Circulating CTLA-4 levels and CTLA4 polymorphisms associate with disease condition and progression and hepatocellular carcinoma patients' survival in chronic hepatitis B virus infection.

Mar 13, 2020

CTLA-4 is involved in the immune dysfunction of hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC). This study analyzed the association of circulating CTLA-4 levels and CTLA4 polymor...

Phenotypic testing of patient herpes simplex virus type 1 and 2 isolates for acyclovir resistance by a novel method based on real-time cell analysis.

Mar 13, 2020

Acyclovir (ACV) is the most commonly used drug for herpes simplex virus (HSV) infection therapy. Prolonged antiviral therapy or prophylaxis in immunocompromised patients may promote the development of...

Multi-modal immune phenotyping of maternal peripheral blood in normal human pregnancy.

Mar 13, 2020

Changes in maternal immunity during pregnancy can result in an altered immune state and, as a natural perturbation, this provides an opportunity to understand functional interactions of the immune sys...

Common genetic variants in ADCY5 and gestational glycemic traits.

Mar 13, 2020

Two meta-analysis of genome wide association studies identified two variants at adenylate cyclase 5 (ADCY5) associated with type 2 diabetes mellitus, fasting and 2-hour glucose in non-pregnant individ...

Potential new tool for anemia screening: An evaluation of the performance and usability of the TrueHb Hemometer.

Mar 13, 2020

In low- and middle-income countries, many women experience anemia during pregnancy due to insufficient dietary intake of key micronutrients, parasitic infections, hemoglobinopathies, and chronic infec...

'Supporting a first-time mother': Assessment of success of a breastfeeding promotion programme.

Mar 13, 2020

The aim of this study was to measure the effectiveness on breast feeding rates by the program 'Supporting a First-time Mother', a web-based platform of interactionbetween first-time mothers and breast...

GeneReader NGS System Is a Useful Sequencing Platform for Clinical Testing of and .

Mar 13, 2020

Although next-generation sequencing (NGS) is widely used for sequencing analysis, it involves a fragmented workflow along with complex bioinformatic analysis and interpretation. In this study, the pe...

Parity as a Prognostic Factor in Patients with Advanced-Stage Epithelial Ovarian Cancer.

Mar 13, 2020

This study aimed to determine the prognostic factors influencing the overall survival (OS) of Iranian women with epithelial ovarian cancer (EOC).Information about newly diagnosed patients with confirm...

Tumor-derived exosomes in the regulation of macrophage polarization.

Mar 13, 2020

This review focuses on exosomes derived from various cancer cells. The review discusses the possibility of differentiating macrophages in alternatively activated anti-inflammatory pro-tumorigenic M2 m...

Association of Germline Variant Status With Therapy Response in High-risk Early-Stage Breast Cancer: A Secondary Analysis of the GeparOcto Randomized Clinical Trial.

Mar 13, 2020

The GeparOcto randomized clinical trial compared the efficacy of 2 neoadjuvant breast cancer (BC) treatment regimens: sequential intense dose-dense epirubicin, paclitaxel, and cyclophosphamide (iddEPC...

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