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OB/GYN General

Diagnostic Accuracy of the Mean Platelet Volume in the Prediction of Upper Urinary Tract Infections.

Mar 13, 2020

The studies have reported that mean platelet volume may be a marker in the discrimination of upper and lower urinary tract infections. We investigated whether the mean platelet volume was a reliable i...

Relationship between desire to void and bladder capacity and rectal sensory function in patients with multiple sclerosis and anorectal disorders.

Mar 13, 2020

The primary aim of this study was to assess the relationship between a strong desire to void (SDV) and rectal sensory function in patients with multiple sclerosis (PwMS) and anorectal disorders. The s...

Diminished hepatic IFN response following HCV clearance triggers HBV reactivation in coinfection.

Mar 13, 2020

In patients with HBV and HCV coinfection, HBV reactivation leading to severe hepatitis has been reported with the use of direct-acting antivirals (DAAs) to treat HCV infection. Here we study the molec...

Real world clinical practice in treating advanced hepatocellular carcinoma: When East meets West.

Mar 13, 2020

The Barcelona Clinic Liver Cancer (BCLC) stage C (BCLC C) of hepatocellular carcinoma (HCC) includes a heterogeneous population for which sorafeninb is one of the recommended therapies. We aim to eval...

De-intensification of therapy in human papillomavirus associated oropharyngeal cancer: A systematic review of prospective trials.

Mar 13, 2020

Numerous trials have been launched over the prior decade examining the safety and efficacy of therapy de-escalation in human papillomavirus (HPV)-associated oropharyngeal cancer (OPC). Because no summ...

Circulating CTLA-4 levels and CTLA4 polymorphisms associate with disease condition and progression and hepatocellular carcinoma patients' survival in chronic hepatitis B virus infection.

Mar 13, 2020

CTLA-4 is involved in the immune dysfunction of hepatitis B virus (HBV) infection and hepatocellular carcinoma (HCC). This study analyzed the association of circulating CTLA-4 levels and CTLA4 polymor...

Phenotypic testing of patient herpes simplex virus type 1 and 2 isolates for acyclovir resistance by a novel method based on real-time cell analysis.

Mar 13, 2020

Acyclovir (ACV) is the most commonly used drug for herpes simplex virus (HSV) infection therapy. Prolonged antiviral therapy or prophylaxis in immunocompromised patients may promote the development of...

Multi-modal immune phenotyping of maternal peripheral blood in normal human pregnancy.

Mar 13, 2020

Changes in maternal immunity during pregnancy can result in an altered immune state and, as a natural perturbation, this provides an opportunity to understand functional interactions of the immune sys...

Common genetic variants in ADCY5 and gestational glycemic traits.

Mar 13, 2020

Two meta-analysis of genome wide association studies identified two variants at adenylate cyclase 5 (ADCY5) associated with type 2 diabetes mellitus, fasting and 2-hour glucose in non-pregnant individ...

Potential new tool for anemia screening: An evaluation of the performance and usability of the TrueHb Hemometer.

Mar 13, 2020

In low- and middle-income countries, many women experience anemia during pregnancy due to insufficient dietary intake of key micronutrients, parasitic infections, hemoglobinopathies, and chronic infec...

'Supporting a first-time mother': Assessment of success of a breastfeeding promotion programme.

Mar 13, 2020

The aim of this study was to measure the effectiveness on breast feeding rates by the program 'Supporting a First-time Mother', a web-based platform of interactionbetween first-time mothers and breast...

GeneReader NGS System Is a Useful Sequencing Platform for Clinical Testing of and .

Mar 13, 2020

Although next-generation sequencing (NGS) is widely used for sequencing analysis, it involves a fragmented workflow along with complex bioinformatic analysis and interpretation. In this study, the pe...

Parity as a Prognostic Factor in Patients with Advanced-Stage Epithelial Ovarian Cancer.

Mar 13, 2020

This study aimed to determine the prognostic factors influencing the overall survival (OS) of Iranian women with epithelial ovarian cancer (EOC).Information about newly diagnosed patients with confirm...

Tumor-derived exosomes in the regulation of macrophage polarization.

Mar 13, 2020

This review focuses on exosomes derived from various cancer cells. The review discusses the possibility of differentiating macrophages in alternatively activated anti-inflammatory pro-tumorigenic M2 m...

Association of Germline Variant Status With Therapy Response in High-risk Early-Stage Breast Cancer: A Secondary Analysis of the GeparOcto Randomized Clinical Trial.

Mar 13, 2020

The GeparOcto randomized clinical trial compared the efficacy of 2 neoadjuvant breast cancer (BC) treatment regimens: sequential intense dose-dense epirubicin, paclitaxel, and cyclophosphamide (iddEPC...

Long non-coding RNA RHPN1-AS1 promotes tumorigenesis and metastasis of ovarian cancer by acting as a ceRNA against miR-596 and upregulating LETM1.

Mar 13, 2020

In recent decades, long non-coding RNAs (lncRNAs) have been reported as crucial functional regulators involved in ovarian cancer. In the present study, we explored how lncRNA RHPN1-AS1 influences the ...

ICSI does not improve reproductive outcomes in autologous ovarian response cycles with non-male factor subfertility.

Mar 13, 2020

Does the method of fertilisation improve reproductive outcomes in poor ovarian response (POR) cycles when compared to all other ovarian response categories in the absence of male factor subfertility?I...

Rectal disc resection improves stool frequency in patients with deep infiltrating endometriosis: A prospective study.

Mar 13, 2020

Gastrointestinal symptoms occur with deeply infiltrating endometriosis (DIE) of the rectum.To explore the medium-term gastrointestinal functional outcomes after rectal disc resection for endometriosis...

The effect of type of oral contraceptive pill and duration of use on fresh and cumulative live birth rates in IVF/ICSI cycles.

Mar 13, 2020

Are there any differences in the fresh (LB) and cumulative live birth rates (CLBR) of women undergoing controlled ovarian stimulation (COS) for IVF/ICSI following pretreatment with different types of ...

Body Mass Index and Polycystic Ovary Syndrome: A Two-sample Bidirectional Mendelian Randomization Study.

Mar 13, 2020

Observational studies have shown a link between elevated body mass index (BMI) and the risk of polycystic ovary syndrome (PCOS). While Mendelian randomization (MR) studies in Europeans have suggested ...

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