Feb 28, 2020

We aim to test whether resilience mediates the association of fear of progression (FoP) with quality of life (QoL) among ovarian cancer patients in China.We collected 230 questionnaires from the First...

Feb 28, 2020

CUB-domain containing protein 1 (CDCP1) is a cancer associated cell surface protein that amplifies pro-tumorigenic signalling by other receptors including EGFR and HER2. Its potential as a cancer targ...

Feb 28, 2020

Metastasis is one of the main causes of death and treatment failure in ovarian cancer. Some small molecule inhibitors can effectively inhibit the metastasis of primary tumors. However, they do not kil...

Feb 28, 2020

is a well-known Indian medicinal herb, and a carbazole alkaloid (mahanine) from this plant causes apoptosis in cancer cells. Here, we investigated how seasonal and geographical variations influence c...

Feb 28, 2020

Epidemiological studies on magnesium intake and primary liver cancer (PLC) are scarce, and no prospective studies have examined the associations of magnesium intake with PLC incidence and mortality. W...

Feb 28, 2020

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women during reproductive age. It is characterised clinically by oligo-ovulation or anovulation, hyper-androgenism, and the pr...

Feb 28, 2020

Mindfulness-based interventions have been receiving growing attention in cancer care.The purpose of this randomized controlled trial is to examine the effectiveness of mindfulness-based cognitive ther...

Feb 28, 2020

ESR1 mutations in breast cancer are known as one of the mechanisms of resistance to aromatase inhibitors. These mutations often occur in the hotspot regions in the ligand binding domain (LBD), but com...

Feb 28, 2020

Historically, breast cancer has been regarded as an immunogenic "cold" tumor hence it has not experienced the explosion of immunotherapy. However, the discovery of immune checkpoint inhibitors has mad...

Feb 28, 2020

The purpose of this study was to identify germline single nucleotide polymorphisms (SNPs) that optimally predict radiation-associated contralateral breast cancer (RCBC) and to provide new biological i...

Feb 28, 2020

 Analysis of the influence of the singular risk factors age and breast density on the 2-year incidence of breast cancer among participants in the German mammography screening program. The multicen...

Feb 28, 2020

After menopause women experience vaginal atrophy related to hormonal changes and estrogen deficiency. The purpose of this paper was to evaluate the effect of the fractional CO laser on the quality of...

Feb 28, 2020

Menopausal vasomotor symptoms (VMS) may result from altered thermoregulatory control in brain regions innervated by neurokinin 3 receptor-expressing neurons. This phase 2b study evaluated seven dosing...

Feb 28, 2020

Quality of life improvement stands as one of the main goals of the medical sciences. Increasing cancer survival rates associated with better early detection and extended therapeutic options led to the...

Feb 28, 2020

This study aims to investigate the mechanism of action of pelvic floor muscle training (PFMT) for the improvement of the signs and symptoms of genitourinary syndrome of menopause (GSM) in postmenopau...

Feb 28, 2020

Infertility is defined as the inability of couples to have a baby after one year of regular unprotected intercourse, affecting 10 to 15% of couples. According to the latest WHO statistics, approximate...

Feb 28, 2020

A common side effect of chemotherapy in breast cancer is early menopause in premenopausal patients, which is mainly a result of an indirect form of ovarian ablation, and is associated with substantial...

Feb 28, 2020

To determine the rate of significant endometrial abnormalities in premenopausal women at low risk for endometrial hyperplasia and cancer presenting with abnormal uterine bleeding (AUB).This descriptiv...

Feb 28, 2020

Are the primary cell cultures and cell lines used in endometriosis research of sufficient quality?Primary cells used in endometriosis research lack purity and phenotypic characterisation, and cell lin...

Feb 28, 2020

Antenatal corticosteroids administered to the mother prior to birth decrease the risk of mortality and major morbidity in infants born at less than 35 weeks' gestation. However, the evidence relating ...