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OB/GYN General

Effects of a ketogenic diet in overweight women with polycystic ovary syndrome.

Feb 28, 2020

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women during reproductive age. It is characterised clinically by oligo-ovulation or anovulation, hyper-androgenism, and the pr...

Mindfulness-based Cognitive Therapy for Psychological Distress, Fear of Cancer Recurrence, Fatigue, Spiritual Wellbeing and Quality of Life in Patients with Breast Cancer - a Randomized Control Trial.

Feb 28, 2020

Mindfulness-based interventions have been receiving growing attention in cancer care.The purpose of this randomized controlled trial is to examine the effectiveness of mindfulness-based cognitive ther...

Molecular Barcode Sequencing of the Whole Ligand Binding Domain of the ESR1 Gene in Cell-Free DNA from Patients with Metastatic Breast Cancer.

Feb 28, 2020

ESR1 mutations in breast cancer are known as one of the mechanisms of resistance to aromatase inhibitors. These mutations often occur in the hotspot regions in the ligand binding domain (LBD), but com...

Breast cancer immunology and immunotherapy: targeting the programmed cell death protein-1/programmed cell death protein ligand-1.

Feb 28, 2020

Historically, breast cancer has been regarded as an immunogenic "cold" tumor hence it has not experienced the explosion of immunotherapy. However, the discovery of immune checkpoint inhibitors has mad...

Machine learning on genome-wide association studies to predict the risk of radiation-associated contralateral breast cancer in the WECARE Study.

Feb 28, 2020

The purpose of this study was to identify germline single nucleotide polymorphisms (SNPs) that optimally predict radiation-associated contralateral breast cancer (RCBC) and to provide new biological i...

Stratifizierung des Brustkrebsrisikos hinsichtlich der Einflüsse von Alter und mammografischer Dichte.

Feb 28, 2020

 Analysis of the influence of the singular risk factors age and breast density on the 2-year incidence of breast cancer among participants in the German mammography screening program. The multicen...

Effect of the Fractional CO Laser on the Quality of Life, General Health, and Genitourinary Symptoms in Postmenopausal Women With Vaginal Atrophy: A Prospective Cohort.

Feb 28, 2020

After menopause women experience vaginal atrophy related to hormonal changes and estrogen deficiency. The purpose of this paper was to evaluate the effect of the fractional CO laser on the quality of...

A phase 2b, randomized, placebo-controlled, double-blind, dose-ranging study of the neurokinin 3 receptor antagonist fezolinetant for vasomotor symptoms associated with menopause.

Feb 28, 2020

Menopausal vasomotor symptoms (VMS) may result from altered thermoregulatory control in brain regions innervated by neurokinin 3 receptor-expressing neurons. This phase 2b study evaluated seven dosing...

State of the Art in Fertility Preservation for Female Patients Prior to Oncologic Therapies.

Feb 28, 2020

Quality of life improvement stands as one of the main goals of the medical sciences. Increasing cancer survival rates associated with better early detection and extended therapeutic options led to the...

Pelvic floor muscle training: mechanisms of action for the improvement of genitourinary syndrome of menopause.

Feb 28, 2020

This study aims to investigate the mechanism of action of pelvic floor muscle training (PFMT) for the improvement of the signs and symptoms of genitourinary syndrome of menopause (GSM) in postmenopau...

Some of the Factors Involved in Male Infertility: A Prospective Review.

Feb 28, 2020

Infertility is defined as the inability of couples to have a baby after one year of regular unprotected intercourse, affecting 10 to 15% of couples. According to the latest WHO statistics, approximate...

Controversies Regarding Ovarian Suppression and Infertility in Early Stage Breast Cancer.

Feb 28, 2020

A common side effect of chemotherapy in breast cancer is early menopause in premenopausal patients, which is mainly a result of an indirect form of ovarian ablation, and is associated with substantial...

Rate of Significant Endometrial Pathology in Women at Low Risk for Endometrial Hyperplasia or Cancer Presenting with Abnormal Uterine Bleeding.

Feb 28, 2020

To determine the rate of significant endometrial abnormalities in premenopausal women at low risk for endometrial hyperplasia and cancer presenting with abnormal uterine bleeding (AUB).This descriptiv...

Endometriotic cell culture contamination and authenticity: a source of bias in in vitro research?

Feb 28, 2020

Are the primary cell cultures and cell lines used in endometriosis research of sufficient quality?Primary cells used in endometriosis research lack purity and phenotypic characterisation, and cell lin...

Patterns of antenatal corticosteroid administration in a cohort of women with diabetes in pregnancy.

Feb 28, 2020

Antenatal corticosteroids administered to the mother prior to birth decrease the risk of mortality and major morbidity in infants born at less than 35 weeks' gestation. However, the evidence relating ...

When a Stroke is not Just a Stroke: Meningitis with Ventriculitis and Vasculitis: A Case Report.

Feb 28, 2020

Community-acquired ventriculitis is considered a rare condition. Central nervous system (CNS) infection due to gram-negative bacilli is usually associated with previous neurosurgical interventions. T...

The oxidative fumarase FumC is a key contributor for E. coli fitness under iron-limitation and during UTI.

Feb 28, 2020

The energy required for a bacterium to grow and colonize the host is generated by metabolic and respiratory functions of the cell. Proton motive force, produced by these processes, drives cellular mec...

Case of catatonia misdiagnosed with coma.

Feb 25, 2020

Catatonia is a state of high-degree psychomotor inhibition in which patients often maintain a constant fixed posture, and generally have unconscious obstacles and various reflex preservation. Patients...

Evaluation of Renal Disease in Patients With Cirrhosis.

Feb 25, 2020

Renal dysfunction in cirrhosis is common and is associated with increased mortality. Identifying and treating reversible causes of renal disease can significantly improve outcomes. The etiology, appro...

Evaluation of durability of a single-dose of the bivalent HPV vaccine: the CVT Trial.

Feb 25, 2020

Investigate the durability of vaccine efficacy (VE) against HPV16/18 infections and antibody response among non-randomized women who received a single-dose of the bivalent HPV vaccine compared to wome...

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