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OB/GYN General

A randomized controlled trial of a lifestyle intervention with longitudinal follow up on ovarian dysmorphology in women with polycystic ovary syndrome.

Feb 25, 2020

Effects of lifestyle modification on reproductive function in polycystic ovary syndrome (PCOS) remains poorly elucidated. We compared the effects of a pulse-based diet (lentils, beans, split-peas, and...

Polyamine stimulation perturbs intracellular Ca2+ homeostasis and decreases viability of breast cancer BT474 cells.

Feb 25, 2020

Intracellular polyamines such as spermine and spermidine are essential to cell growth in normal and especially in cancer cells. However, whether extracellular polyamines affect cancer cell survival is...

Drug-loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic Cancer Therapy.

Feb 25, 2020

In this study we have developed biodegradable polymeric nanoparticles (NPs) containing the cytostatic drugs mertansine (MRT) or cabazitaxel (CBZ).The NPs are based on chitosan (CS) conjugate polymers ...

Biological Activity and Apoptotic Signaling Pathway of C- Functionalized Cephalostatin 1 Analogues.

Feb 25, 2020

Cephalostatin 1, a potent anti-cancer agent, is a natural bis-steroidal alkaloid that causes cell death in the subnanomolar to picomolar ranges via an atypical apoptosis pathway. Although cephalostati...

Association of BRCA Mutantations and BRCAness Status With Anticancer Drug Sensitivities in Triple-Negative Breast Cancer Cell Lines.

Feb 25, 2020

Many triple-negative breast cancers (TNBCs) show impaired breast cancer susceptibility gene I (BRCA1) function, called BRCAness. BRCAness tumors may show similar sensitivities to anticancer drugs as t...

Continuation of Annual Screening Mammography and Breast Cancer Mortality in Women Older Than 70 Years.

Feb 25, 2020

Randomized trials have shown that initiating breast cancer screening between ages 50 and 69 years and continuing it for 10 years decreases breast cancer mortality. However, no trials have studied whet...

Medical Student Experiences With Accessing and Entering Patient Information in Electronic Health Records During the Ob/Gyn Clerkship.

Feb 25, 2020

Medical school graduates should be able to enter information from patient encounters and to write orders and prescriptions in the electronic health record. Studies have shown that while students often...

Health Care for Transgender Men: What Is Missing in OB/GYN Care?

Feb 25, 2020

Transgender men (TGM) are those who identify their sex as male but were assigned female at birth who face marginalization in obstetrics and gynecology (OB/GYN) practices. The following commentary high...

Accuracy in Referrals to Gynecologic Oncologists Based on Clinical Presentation for Ovarian Mass.

Feb 25, 2020

Ovarian cancer is one of the most lethal gynecological cancers in women due to late diagnosis. Despite technological advancements, experienced physicians have high sensitivities and specificities in s...

A Retrospective Study on Risk Factors for Urinary Tract Infection in Patients with Intracranial Cerebral Hemorrhage.

Feb 25, 2020

This study aimed to explore the risk factors of urinary tract infection (UTI) in patients with intracranial cerebral hemorrhage (ICH).This is a retrospective study, and a total of 77 patients with ICH...

Clinical impact of rapid susceptibility testing on Mueller-Hinton Rapid-SIR directly from urine specimens.

Feb 25, 2020

Urinary tract infection diagnosis and management generally involves a 48-h microbiological delay to obtain the antibiotic susceptibility test (AST) results. In the context of multidrug resistance, red...

Assessment of the Urinary Microbiome in Children Younger Than 48 Months.

Feb 25, 2020

The urinary tract was once thought to be sterile, and little is known about the urinary microbiome in children. This study aimed to examine the urinary microbiome of young children across demographic ...

Prostate Cancer: Biology, Incidence, Detection Methods, Treatment Methods, and Vaccines.

Feb 25, 2020

Cancer of the prostate are cancers in which most incidences are slow growing and in the U.S., a record of 1.2 million new cases of prostate cancer occurred in 2018. The rates of this type of cancer ha...

2019 American College of Rheumatology Reproductive Health in Rheumatic and Musculoskeletal Diseases Guideline.

Feb 25, 2020

To develop an evidence-based guideline for rheumatic and musculoskeletal disease (RMD) patients regarding contraception; assisted reproductive technology (ART); fertility preservation; pregnancy asses...

Dissatisfaction of women with induction of labour according to parity: Results of a population-based cohort study.

Feb 25, 2020

To determine the factors associated with dissatisfaction in women whose labour was induced, according to parity.Prospective population-based cohort study.Seven French perinatal health networks includi...

Effect of app-based audio guidance pelvic floor muscle training on treatment of stress urinary incontinence in primiparas: A randomized controlled trial.

Feb 18, 2020

Stress urinary incontinence is a distressing and burdensome condition affecting approximately one third of pregnant women and pelvic floor muscle training is recommended as the first-line treatment. C...

Which pelvic floor muscle functions are associated with improved subjective and objective symptoms after 8 weeks of surface electrical stimulation in women with stress urinary incontinence?

Feb 18, 2020

Stress urinary incontinence (SUI) is defined as involuntary urine loss during effort, sneezing, or coughing. We investigated which pelvic floor muscle (PFM) functions (muscle strength, power, and endu...

Development of a fall-risk assessment profile for community-dwelling older adults by using the National Health Interview Survey in Taiwan.

Feb 18, 2020

Falls represent a global health issue among older adults and cause a considerable burden on medical systems. In this study, a fall-risk assessment profile was developed for community-dwelling older ad...

Joint report on the terminology for surgical procedures to treat stress urinary incontinence in women.

Feb 18, 2020

Standardized terminology for surgical procedures commonly performed to treat stress urinary incontinence in women is needed to facilitate research, clinical care, and teaching in female pelvic medicin...

A positive nitrite test was an independent risk factor for invasive bacterial infections in infants under 90 days of age with fever without source.

Feb 18, 2020

This study analysed the association between a positive nitrite dipstick test and an invasive bacterial infection (IBI) in infants younger than 90 days of age with fever without source (FWS).We perform...

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