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OB/GYN General

Ovariectomy provokes inflammatory and cardiovascular effects of endotoxemia in rats: Dissimilar benefits of hormonal supplements.

Feb 25, 2020

The female gender is protected against immunological complications of endotoxemia. Here we investigated whether gonadal hormone depletion by ovariectomy (OVX) uncovers inflammatory and cardiovascular ...

Impact of Bariatric Surgery on Clinical, Biochemical, and Hormonal Parameters in Women with Polycystic Ovary Syndrome (PCOS).

Feb 25, 2020

There is limited data on the impact of bariatric surgery on polycystic ovarian syndrome (PCOS) especially in the Indian population.To study the impact of bariatric surgery in women with PCOS in terms ...

Management of endometriosis-related infertility: Considerations and treatment options.

Feb 25, 2020

Endometriosis is a common inflammatory disease in women of reproductive age and is one of the major causes of infertility. Endometriosis causes a sustained reduction of ovarian reserve through both ph...

Disseminated Endometriosis and Low-Grade Endometrioid Stromal Sarcoma in a Patient with a History of Uterine Morcellation for Adenomyosis.

Feb 25, 2020

Morcellation of benign uterine tumors allows for removal of the tumors via minimally invasive laparoscopic procedures. However, in rare cases, morcellation has been associated with upstaging of unexpe...

Producing Parenthood: Islamic Bioethical Perspectives & Normative Implications.

Feb 25, 2020

Biomedicine has opened up new possibilities for parenthood. Once resigned to remaining childless or pursuing adoption, infertile couples can now pursue options such as gamete donation, in-vitro fertil...

A randomized controlled trial of a lifestyle intervention with longitudinal follow up on ovarian dysmorphology in women with polycystic ovary syndrome.

Feb 25, 2020

Effects of lifestyle modification on reproductive function in polycystic ovary syndrome (PCOS) remains poorly elucidated. We compared the effects of a pulse-based diet (lentils, beans, split-peas, and...

Polyamine stimulation perturbs intracellular Ca2+ homeostasis and decreases viability of breast cancer BT474 cells.

Feb 25, 2020

Intracellular polyamines such as spermine and spermidine are essential to cell growth in normal and especially in cancer cells. However, whether extracellular polyamines affect cancer cell survival is...

Drug-loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic Cancer Therapy.

Feb 25, 2020

In this study we have developed biodegradable polymeric nanoparticles (NPs) containing the cytostatic drugs mertansine (MRT) or cabazitaxel (CBZ).The NPs are based on chitosan (CS) conjugate polymers ...

Biological Activity and Apoptotic Signaling Pathway of C- Functionalized Cephalostatin 1 Analogues.

Feb 25, 2020

Cephalostatin 1, a potent anti-cancer agent, is a natural bis-steroidal alkaloid that causes cell death in the subnanomolar to picomolar ranges via an atypical apoptosis pathway. Although cephalostati...

Association of BRCA Mutantations and BRCAness Status With Anticancer Drug Sensitivities in Triple-Negative Breast Cancer Cell Lines.

Feb 25, 2020

Many triple-negative breast cancers (TNBCs) show impaired breast cancer susceptibility gene I (BRCA1) function, called BRCAness. BRCAness tumors may show similar sensitivities to anticancer drugs as t...

Continuation of Annual Screening Mammography and Breast Cancer Mortality in Women Older Than 70 Years.

Feb 25, 2020

Randomized trials have shown that initiating breast cancer screening between ages 50 and 69 years and continuing it for 10 years decreases breast cancer mortality. However, no trials have studied whet...

Medical Student Experiences With Accessing and Entering Patient Information in Electronic Health Records During the Ob/Gyn Clerkship.

Feb 25, 2020

Medical school graduates should be able to enter information from patient encounters and to write orders and prescriptions in the electronic health record. Studies have shown that while students often...

Health Care for Transgender Men: What Is Missing in OB/GYN Care?

Feb 25, 2020

Transgender men (TGM) are those who identify their sex as male but were assigned female at birth who face marginalization in obstetrics and gynecology (OB/GYN) practices. The following commentary high...

Accuracy in Referrals to Gynecologic Oncologists Based on Clinical Presentation for Ovarian Mass.

Feb 25, 2020

Ovarian cancer is one of the most lethal gynecological cancers in women due to late diagnosis. Despite technological advancements, experienced physicians have high sensitivities and specificities in s...

A Retrospective Study on Risk Factors for Urinary Tract Infection in Patients with Intracranial Cerebral Hemorrhage.

Feb 25, 2020

This study aimed to explore the risk factors of urinary tract infection (UTI) in patients with intracranial cerebral hemorrhage (ICH).This is a retrospective study, and a total of 77 patients with ICH...

Clinical impact of rapid susceptibility testing on Mueller-Hinton Rapid-SIR directly from urine specimens.

Feb 25, 2020

Urinary tract infection diagnosis and management generally involves a 48-h microbiological delay to obtain the antibiotic susceptibility test (AST) results. In the context of multidrug resistance, red...

Assessment of the Urinary Microbiome in Children Younger Than 48 Months.

Feb 25, 2020

The urinary tract was once thought to be sterile, and little is known about the urinary microbiome in children. This study aimed to examine the urinary microbiome of young children across demographic ...

Prostate Cancer: Biology, Incidence, Detection Methods, Treatment Methods, and Vaccines.

Feb 25, 2020

Cancer of the prostate are cancers in which most incidences are slow growing and in the U.S., a record of 1.2 million new cases of prostate cancer occurred in 2018. The rates of this type of cancer ha...

2019 American College of Rheumatology Reproductive Health in Rheumatic and Musculoskeletal Diseases Guideline.

Feb 25, 2020

To develop an evidence-based guideline for rheumatic and musculoskeletal disease (RMD) patients regarding contraception; assisted reproductive technology (ART); fertility preservation; pregnancy asses...

Dissatisfaction of women with induction of labour according to parity: Results of a population-based cohort study.

Feb 25, 2020

To determine the factors associated with dissatisfaction in women whose labour was induced, according to parity.Prospective population-based cohort study.Seven French perinatal health networks includi...

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