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OB/GYN General

Modified Linear Peptides Effectively Silence STAT-3 in Breast Cancer and Ovarian Cancer Cell Lines.

Feb 27, 2023

RNA interference (RNAi) has drawn enormous attention as a powerful tool because of its capability to interfere with mRNA and protein production. However, designing a safe and efficient delivery system...

The potential of RAS/RAF/MEK/ERK (MAPK) signaling pathway inhibitors in ovarian cancer: A systematic review and meta-analysis.

Feb 27, 2023

The RAS/RAF/MEK/ERK (MAPK) pathway plays a role in ovarian carcinogenesis. Low-grade serous ovarian carcinoma (LGSOC) frequently harbors activating MAPK mutations. MAPK inhibitors have been used in sm...

PD-1/PD-L1 blockade inhibits epithelial-mesenchymal transition and improves chemotherapeutic response in breast cancer.

Feb 27, 2023

Therapies targeting the PD-1/PD-L1 axis have recently been implemented for triple negative breast cancer (TNBC) management with limited efficacy, indicating that this axis may promote tumor growth by ...

Comparison of a U.S. and Zambian Ob/Gyn Residency Training Programme.

Feb 27, 2023

The major objective of the study was to compare and contrast a U.S. and Zambian Ob/Gyn residency programme, using uniform metrics, as the basis for an initial exploration of perceived inequities in po...

Current status and problems in the diagnosis and treatment of premenstrual syndrome and premenstrual dysphoric disorder from the perspective of obstetricians and gynecologists in Japan.

Feb 27, 2023

To investigate the current status and problems in the diagnosis and treatment of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) from the perspective of obstetricians and gyneco...

Incidence of Intra-amniotic Infection in Preterm Birth: Noninvasive Prediction Models

Feb 22, 2023

The following is a summary of "Noninvasive prediction models of intra-amniotic infection in women with preterm labor," published in the JANUARY 2023 issue of Obstetrics and Gynecology by Cobo, et al. ...

Availability of Gynecologic Oncologists and Obstetric-gynecologists to US Medicare Patients

Feb 21, 2023

The following is a summary of "Supply of obstetrician–gynecologists and gynecologic oncologists to the US Medicare population: a state-by-state analysis," published in the February 2023 issue of Obs...

Clinical Risk Factors of Negative Outcomes in Pregnant and Postpartum COVID-19 Women

Feb 20, 2023

The following is a summary of "Clinical risk factors of adverse outcomes among women with COVID-19 in the pregnancy and postpartum period: a sequential, prospective meta-analysis," published in the Fe...

Effects of ulinastatin therapy in emergency severe multiple trauma: A single-center randomized controlled trial.

Feb 20, 2023

Severe multiple traumas are one of the most common diseases and carry a significant financial burden with high disability and mortality. There are no effective drugs in the clinical management of seve...

Feasibility of anterior lobe-preserving transurethral enucleation and resection of prostate on improving urinary incontinence in patients with benign prostatic hyperplasia: A retrospective cohort study.

Feb 20, 2023

Transurethral enucleation and resection of prostate (TUERP), as one of the conventional surgical methods for patients with benign prostatic hyperplasia (BPH), usually resulted in pseudo urinary incont...

Wilson disease in pregnancy: A case series.

Feb 20, 2023

Hepatolenticular degeneration, also known as Wilson disease (WD), is an autosomal recessive inherited disease characterized by copper metabolism, which has complex clinical manifestations, and mainly ...

The expression levels of NF-κB and IKKβ in epithelial ovarian cancer and their correlation with drug resistance-related genes MDR1, TOPOII, and ERCC1.

Feb 20, 2023

To explore the expression levels of nuclear factor kappa B (NF-κB) and inhibitor of nuclear factor kappa B kinase (IKKβ) in epithelial ovarian cancer and the correlation analysis with multi-drug res...

Multi-maintenance olaparib therapy in relapsed, germline BRCA1/2-mutant high-grade serous ovarian cancer (MOLTO): a phase II trial.

Feb 20, 2023

A single maintenance course of a poly(ADP-ribose) polymerase inhibitor (PARPi) improves progression-free survival (PFS) in germline BRCA1/2-mutant high-grade serous ovarian cancer (gBRCAm-HGSOC). The ...

Association of endometriosis with cardiovascular disease: Genetic aspects (Review).

Feb 20, 2023

Cardiovascular disease (CVD) comprises a broad spectrum of pathological conditions that affect the heart or blood vessels, including sequelae that arise from damaged vasculature in other organs of the...

Screening and identification of hub-gene associated with brain metastasis in breast cancer.

Feb 20, 2023

The presence of breast cancer in the brain, also known as brain metastasis (BMS), is the primary reason for a bad prognosis in cases of breast cancer. Breast cancer is the most prevalent malignant tum...

Understanding factors that influence whether a woman will seek care for reproductive health: A national survey.

Feb 20, 2023

A number of studies have characterized the importance of regular OB/GYN visits for women who are above the age of 18. As more emphasis is placed on reproductive healthcare, there has been an overall d...

Deep learning for the ovarian lesion localization and discrimination between borderline and malignant ovarian tumors based on routine MR imaging.

Feb 20, 2023

To establish a deep learning (DL) model in differentiating borderline ovarian tumor (BOT) from epithelial ovarian cancer (EOC) on conventional MR imaging. We retrospectively enrolled 201 patients of 1...

Implications for COVID-19 Practice Regarding Semen Parameters and Fertility Outcomes

Feb 17, 2023

The following is a summary of "Effect of semen collection location on semen parameters and fertility outcomes and implications for practice in the COVID-19 era: a systematic review and meta-analysis o...

Maternal Blood cfDNA and AI: Accurate Prenatal Diagnosis of Fetal CHD

Feb 16, 2023

The following is a summary of "Cell-free DNA in maternal blood and artificial intelligence: accurate prenatal detection of fetal congenital heart defects," published in the January 2023 issue of Obste...

Analyzing Features of Molecular Luteal and IVF in Cancer Patients

Feb 15, 2023

The following is the summary of “IVF characteristics and the molecular luteal features of random start IVF cycles are not different from conventional cycles in cancer patients” published in the Ja...

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