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OB/GYN General

Adipocyte-derived exosomal miR-30c-5p promotes ovarian angiogenesis in polycystic ovary syndrome via the SOCS3/STAT3/VEGFA pathway.

Mar 06, 2023

Polycystic ovary syndrome (PCOS) is a systemic endocrine disease affecting women's reproductive health. Ovarian angiogenesis in PCOS patients is abnormal, manifested by increased ovarian stromal vascu...

Prediction of Volume Decrease in Uterine Leiomyomas with MED12 Mutations by Agonists of Gonadotropin-releasing Hormone

Mar 02, 2023

The following is a summary of "MED12 mutations in uterine leiomyomas: prediction of volume reduction by gonadotropin-releasing hormone agonists," published in the FEBRUARY 2023 issue of Obstetrics and...

Evaluating the Benefits of Total Laparoscopic Hysterectomy with Longer Operative Time Vs. Total Abdominal Hysterectomy

Mar 01, 2023

The following is a summary of "Is total laparoscopic hysterectomy with longer operative time associated with a decreased benefit compared with total abdominal hysterectomy?," published in the FEBRUARY...

PETN Impact on the Onset of Fetal Growth Restriction in Pregnancies with Compromised Uteroplacental Perfusion at Midgestation

Feb 28, 2023

The following is a summary of "Effect of pentaerythritol tetranitrate (PETN) on the development of fetal growth restriction in pregnancies with impaired uteroplacental perfusion at midgestation—a ra...

The Effects of Prenatal Corticosteroids on the Long-term Development of Term Newborns

Feb 27, 2023

The following is a summary of "Long-term childhood outcomes for babies born at term who were exposed to antenatal corticosteroids," published in the JANUARY 2023 issue of Obstetrics and Gynecology by ...

Association between pre-surgical weight status and urinary and sexual function in prostate cancer patients treated by radical prostatectomy: a prospective cohort study.

Feb 27, 2023

To prospectively examine the influence of weight status on urinary and sexual function in clinically localized prostate cancer patients treated by radical prostatectomy (RP).The Prostatectomy, Inconti...

Machine learning model for predicting ciprofloxacin resistance and presence of ESBL in patients with UTI in the ED.

Feb 27, 2023

Increasing antimicrobial resistance in uropathogens is a clinical challenge to emergency physicians as antibiotics should be selected before an infecting pathogen or its antibiotic resistance profile ...

Modified Linear Peptides Effectively Silence STAT-3 in Breast Cancer and Ovarian Cancer Cell Lines.

Feb 27, 2023

RNA interference (RNAi) has drawn enormous attention as a powerful tool because of its capability to interfere with mRNA and protein production. However, designing a safe and efficient delivery system...

The potential of RAS/RAF/MEK/ERK (MAPK) signaling pathway inhibitors in ovarian cancer: A systematic review and meta-analysis.

Feb 27, 2023

The RAS/RAF/MEK/ERK (MAPK) pathway plays a role in ovarian carcinogenesis. Low-grade serous ovarian carcinoma (LGSOC) frequently harbors activating MAPK mutations. MAPK inhibitors have been used in sm...

PD-1/PD-L1 blockade inhibits epithelial-mesenchymal transition and improves chemotherapeutic response in breast cancer.

Feb 27, 2023

Therapies targeting the PD-1/PD-L1 axis have recently been implemented for triple negative breast cancer (TNBC) management with limited efficacy, indicating that this axis may promote tumor growth by ...

Comparison of a U.S. and Zambian Ob/Gyn Residency Training Programme.

Feb 27, 2023

The major objective of the study was to compare and contrast a U.S. and Zambian Ob/Gyn residency programme, using uniform metrics, as the basis for an initial exploration of perceived inequities in po...

Current status and problems in the diagnosis and treatment of premenstrual syndrome and premenstrual dysphoric disorder from the perspective of obstetricians and gynecologists in Japan.

Feb 27, 2023

To investigate the current status and problems in the diagnosis and treatment of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) from the perspective of obstetricians and gyneco...

Incidence of Intra-amniotic Infection in Preterm Birth: Noninvasive Prediction Models

Feb 22, 2023

The following is a summary of "Noninvasive prediction models of intra-amniotic infection in women with preterm labor," published in the JANUARY 2023 issue of Obstetrics and Gynecology by Cobo, et al. ...

Availability of Gynecologic Oncologists and Obstetric-gynecologists to US Medicare Patients

Feb 21, 2023

The following is a summary of "Supply of obstetrician–gynecologists and gynecologic oncologists to the US Medicare population: a state-by-state analysis," published in the February 2023 issue of Obs...

Clinical Risk Factors of Negative Outcomes in Pregnant and Postpartum COVID-19 Women

Feb 20, 2023

The following is a summary of "Clinical risk factors of adverse outcomes among women with COVID-19 in the pregnancy and postpartum period: a sequential, prospective meta-analysis," published in the Fe...

Effects of ulinastatin therapy in emergency severe multiple trauma: A single-center randomized controlled trial.

Feb 20, 2023

Severe multiple traumas are one of the most common diseases and carry a significant financial burden with high disability and mortality. There are no effective drugs in the clinical management of seve...

Feasibility of anterior lobe-preserving transurethral enucleation and resection of prostate on improving urinary incontinence in patients with benign prostatic hyperplasia: A retrospective cohort study.

Feb 20, 2023

Transurethral enucleation and resection of prostate (TUERP), as one of the conventional surgical methods for patients with benign prostatic hyperplasia (BPH), usually resulted in pseudo urinary incont...

Wilson disease in pregnancy: A case series.

Feb 20, 2023

Hepatolenticular degeneration, also known as Wilson disease (WD), is an autosomal recessive inherited disease characterized by copper metabolism, which has complex clinical manifestations, and mainly ...

The expression levels of NF-κB and IKKβ in epithelial ovarian cancer and their correlation with drug resistance-related genes MDR1, TOPOII, and ERCC1.

Feb 20, 2023

To explore the expression levels of nuclear factor kappa B (NF-κB) and inhibitor of nuclear factor kappa B kinase (IKKβ) in epithelial ovarian cancer and the correlation analysis with multi-drug res...

Multi-maintenance olaparib therapy in relapsed, germline BRCA1/2-mutant high-grade serous ovarian cancer (MOLTO): a phase II trial.

Feb 20, 2023

A single maintenance course of a poly(ADP-ribose) polymerase inhibitor (PARPi) improves progression-free survival (PFS) in germline BRCA1/2-mutant high-grade serous ovarian cancer (gBRCAm-HGSOC). The ...

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