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OB/GYN General

Economic Evaluation of Trametinib for Low-grade Serous Ovarian Cancer Patients

Dec 05, 2022

Trametinib improved progression-free survival (PFS) over the standard of care (SOC)  of therapy for patients with recurrent low-grade serous ovarian cancer (LGSOC) was demonstrated in the GOG 281/LOG...

Prevalence and determinants of intention to use modern contraceptives among grand-multiparous women in sub-Saharan Africa.

Dec 05, 2022

Sub-Saharan Africa, characterised by high fertility and low contraceptive use prevalence, remains one of the settings with the poorest maternal and child health indices globally. Studies have establi...

Uterine artery Doppler indices throughout gestation in women with and without previous Cesarean deliveries: a prospective longitudinal case-control study.

Dec 05, 2022

To determine whether a history of previous Cesarean delivery (CD) impacts uterine artery (UtA) Doppler indices throughout pregnancy. Women with and without CD (NCD) were prospectively enrolled for seq...

Genetic screening and analysis of TUBB8 variants in females seeking ART.

Dec 05, 2022

More than 100 variants have been identified in the TUBB8 gene, which account for approximately 30% of infertile women with oocyte maturation defects. But what is the correlation between the highly phe...

Nafamostat Mesylate in Combination with the Mouse Amino-Terminal Fragment of Urokinase-Human Serum Albumin Improves the Treatment Outcome of Triple-Negative Breast Cancer Therapy.

Dec 05, 2022

Triple-negative breast cancer (TNBC) is highly aggressive and causes a higher proportion of metastatic cases. However, therapies directed to specific molecular targets have rarely achieved clinically ...

Primary extensive perianal cutaneous tuberculosis: A challenging diagnosis. Case report and a review of the literature.

Dec 05, 2022

Perianal tuberculosis is extremely rare without previous or active pulmonary infection. Ulcerative skin lesion is a rare presentation of extrapulmonary tuberculosis in the oral, perianal, or genital m...

Combination of isothiocyanates and antibiotics increases susceptibility against Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis and Serratia marcescens.

Dec 05, 2022

The development and spread of multidrug-resistant organisms (MDRO) is evolving rapidly worldwide. Although effective antibiotics are still available, some infections are difficult to treat. Among MDRO...

The role of obstetrician-gynecologists and reproductive endocrinologists in the blood glucose management of polycystic ovary syndrome.

Dec 05, 2022

This study aimed to compare the differences between reproductive endocrinologists (Repro-Endo) and obstetricians-gynecologists (Ob-Gyn; non-reproductive medicine specialty) in diagnosing, evaluating,...

Previable and Periviable Rupture of Membranes Due to Laser Photocoagulation for Twin-Twin Transfusion Syndrome: Pregnancy Outcomes

Dec 02, 2022

For a study, researchers sought to outline the pregnancy outcomes for patients who had therapy for twin-twin transfusion syndrome but nevertheless experienced pre-viable and persistent prelabour ruptu...

Sum of Birth Weights Used to Assess the Risk of Severe Postpartum Hemorrhage in Twin Pregnancies

Dec 02, 2022

For a study, researchers sought to identify the nature of the relationships between birth weights and severe postpartum hemorrhage in twin pregnancies. The JUMODA (JUmeaux Mode d'Accouchement) coho...

Should Endometrial Hyperplasia Patients Continue Mapping Sentinel Lymph Nodes?

Dec 02, 2022

The aim of this study was to evaluate the difference in outcomes between individuals with premalignant endometrial pathology who have a hysterectomy with or without sentinel lymph node (SLN) removal. ...

A Comprehensive Review and Scoping Analysis of Best Cervical Cancer Care

Dec 02, 2022

Cervical cancer survival rates vary widely between regions and countries. When cervical cancer has spread just locally, it is called locally advanced cervical cancer (LACC), and it has a much lower su...

SGO on Wellness, Burnout, and Gynecologic Oncology

Dec 02, 2022

Identifying trends and at-risk demographics among gynecologic oncology doctors regarding wellness and burnout is important for planning future interventions. The results of the 2020 Society of Gynecol...

Evaluating the Relationship Between Fetal Acidosis and Obesity at Scheduled Cesarean Delivery

Dec 01, 2022

For a study, researchers sought to determine if obese individuals who have planned cesarean deliveries under neuraxial anesthesia were more likely to experience umbilical artery pH less than 7.1 and b...

After a Diagnosis of Breast Cancer, Evaluation of Obstetric and Neonatal Outcomes

Dec 01, 2022

For a study, researchers sought to assess the obstetric and neonatal outcomes of the first live birth delivered 1 or more years after receiving a breast cancer diagnosis. In a population-based anal...

Symptomatic Uterine Leiomyomas: Use of Long-term Relugolix Combination Therapy

Dec 01, 2022

Once-daily relugolix combination therapy was well tolerated and reduced menstrual blood loss volume and pain in women with heavy menstrual bleeding associated with uterine leiomyomas in the LIBERTY 1 ...

FMO2, a Fibroblast-derived Prognostic Predictor for Epithelial Ovarian Cancer

Nov 30, 2022

Fibroblasts were extracted from samples of EOC to use as a primary source. For this purpose, researchers obtained expression profiles from microdissection and single-cell RNA sequencing (scRNA-seq) da...

Circulating Metastases DNA Tracking for Ovarian Cancer Recurrence

Nov 30, 2022

The most deadly gynecologic cancer is epithelial ovarian cancer (EOC). Before surgery and during follow-up after therapy, researchers investigated whether circulating tumor DNA (ctDNA) could be a usef...

Endometrial Cancer CTNNB1 and MMP Mutations with Anti-angiogenesis Therapy

Nov 30, 2022

Biomarkers and treatment options for advanced and recurring illnesses are scarce. Although the mechanism of action of bevacizumab, an anti-angiogenesis medication, is uncertain, endometrial malignanci...

An Endometrial Cancer New Biomarker Based on CRABP2

Nov 29, 2022

For a study, the aim was to find out what role increased CRABP2 expression plays in the development and progression of endometrial cancer (EC). Using a decision tree classifier, patients were divided ...

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