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OB/GYN General

Nafamostat Mesylate in Combination with the Mouse Amino-Terminal Fragment of Urokinase-Human Serum Albumin Improves the Treatment Outcome of Triple-Negative Breast Cancer Therapy.

Dec 05, 2022

Triple-negative breast cancer (TNBC) is highly aggressive and causes a higher proportion of metastatic cases. However, therapies directed to specific molecular targets have rarely achieved clinically ...

Combination of isothiocyanates and antibiotics increases susceptibility against Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis and Serratia marcescens.

Dec 05, 2022

The development and spread of multidrug-resistant organisms (MDRO) is evolving rapidly worldwide. Although effective antibiotics are still available, some infections are difficult to treat. Among MDRO...

The role of obstetrician-gynecologists and reproductive endocrinologists in the blood glucose management of polycystic ovary syndrome.

Dec 05, 2022

This study aimed to compare the differences between reproductive endocrinologists (Repro-Endo) and obstetricians-gynecologists (Ob-Gyn; non-reproductive medicine specialty) in diagnosing, evaluating,...

Previable and Periviable Rupture of Membranes Due to Laser Photocoagulation for Twin-Twin Transfusion Syndrome: Pregnancy Outcomes

Dec 02, 2022

For a study, researchers sought to outline the pregnancy outcomes for patients who had therapy for twin-twin transfusion syndrome but nevertheless experienced pre-viable and persistent prelabour ruptu...

Sum of Birth Weights Used to Assess the Risk of Severe Postpartum Hemorrhage in Twin Pregnancies

Dec 02, 2022

For a study, researchers sought to identify the nature of the relationships between birth weights and severe postpartum hemorrhage in twin pregnancies. The JUMODA (JUmeaux Mode d'Accouchement) coho...

Should Endometrial Hyperplasia Patients Continue Mapping Sentinel Lymph Nodes?

Dec 02, 2022

The aim of this study was to evaluate the difference in outcomes between individuals with premalignant endometrial pathology who have a hysterectomy with or without sentinel lymph node (SLN) removal. ...

A Comprehensive Review and Scoping Analysis of Best Cervical Cancer Care

Dec 02, 2022

Cervical cancer survival rates vary widely between regions and countries. When cervical cancer has spread just locally, it is called locally advanced cervical cancer (LACC), and it has a much lower su...

SGO on Wellness, Burnout, and Gynecologic Oncology

Dec 02, 2022

Identifying trends and at-risk demographics among gynecologic oncology doctors regarding wellness and burnout is important for planning future interventions. The results of the 2020 Society of Gynecol...

Evaluating the Relationship Between Fetal Acidosis and Obesity at Scheduled Cesarean Delivery

Dec 01, 2022

For a study, researchers sought to determine if obese individuals who have planned cesarean deliveries under neuraxial anesthesia were more likely to experience umbilical artery pH less than 7.1 and b...

After a Diagnosis of Breast Cancer, Evaluation of Obstetric and Neonatal Outcomes

Dec 01, 2022

For a study, researchers sought to assess the obstetric and neonatal outcomes of the first live birth delivered 1 or more years after receiving a breast cancer diagnosis. In a population-based anal...

Symptomatic Uterine Leiomyomas: Use of Long-term Relugolix Combination Therapy

Dec 01, 2022

Once-daily relugolix combination therapy was well tolerated and reduced menstrual blood loss volume and pain in women with heavy menstrual bleeding associated with uterine leiomyomas in the LIBERTY 1 ...

FMO2, a Fibroblast-derived Prognostic Predictor for Epithelial Ovarian Cancer

Nov 30, 2022

Fibroblasts were extracted from samples of EOC to use as a primary source. For this purpose, researchers obtained expression profiles from microdissection and single-cell RNA sequencing (scRNA-seq) da...

Circulating Metastases DNA Tracking for Ovarian Cancer Recurrence

Nov 30, 2022

The most deadly gynecologic cancer is epithelial ovarian cancer (EOC). Before surgery and during follow-up after therapy, researchers investigated whether circulating tumor DNA (ctDNA) could be a usef...

Endometrial Cancer CTNNB1 and MMP Mutations with Anti-angiogenesis Therapy

Nov 30, 2022

Biomarkers and treatment options for advanced and recurring illnesses are scarce. Although the mechanism of action of bevacizumab, an anti-angiogenesis medication, is uncertain, endometrial malignanci...

An Endometrial Cancer New Biomarker Based on CRABP2

Nov 29, 2022

For a study, the aim was to find out what role increased CRABP2 expression plays in the development and progression of endometrial cancer (EC). Using a decision tree classifier, patients were divided ...

Identification of Ovarian Cancer Therapeutic and Diagnostic Indicators Through Genomic Profiling

Nov 29, 2022

When compared to high grade serous ovarian cancer (HGSOC), low grade serous ovarian cancer (LGSOC) has distinct etiology, molecular, genetic, and clinical features. Limited testing, inconsistent histo...

DNA Methylation Profiling in the Blood for Ovarian Cancer Screening

Nov 29, 2022

Due to insufficient early detection methods, ovarian cancer remains a leading cause of death among gynecological malignancies. Therefore, DNA methylation profiling in blood samples was investigated fo...

HER2 Testing Platforms and Targeted Therapy Implications in Uterine Serous Carcinoma

Nov 28, 2022

Uterine serous carcinoma (USC) has HER2 as a major therapeutic and prognostic target. However, there is a lack of consensus on the best HER2 testing infrastructure, and testing recommendations have ev...

Splenectomy Outcomes During Cytoreductive Surgery for Epithelial Ovarian Cancer

Nov 28, 2022

Complications following cytoreductive surgery for Stage III or IV epithelial ovarian cancer with or without splenectomy are described, and opportunities for better post-splenectomy treatment are highl...

Pelvic Exenteration Outcomes: An Experience with the Brunschwig Procedure in the Current Era

Nov 28, 2022

For a study, it is essential to analyze the postoperative and oncologic results of pelvic exenteration for non-ovarian gynecologic cancers. From January 1, 2010, through December 31, 2019, researchers...

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