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OB/GYN General

cN-/pN+ Vulvar Cancer Treatment: Declining Use of IFL

Sep 14, 2022

Researchers found that when sentinel lymph node biopsy (SLNB) results are positive despite clinically negative groin lymph nodes, there is controversy over how to treat vulvar cancer. Inguinofemoral l...

Cervical Cancer Patients Undergoing Surgical Treatment for Early-Stage Disease Are Protected by Preoperative Conization

Sep 13, 2022

The research was set out to determine whether or not pre-operative conization improved disease-free survival (DFS) in early-stage cervical cancer. This population-based cohort study used data from cli...

Seizure Frequency in Pregnancy More Likely With Focal Epilepsy

Aug 26, 2022

Women with focal epilepsy experienced the greatest risk for increased seizure activity in pregnancy and may require closer monitoring in pregnancy and the postpartum period.   “During...

Endometrial HLA-F Expression: Genotypes & Immune cell infiltration

Aug 10, 2022

Extravillous trophoblast cells express the immunomodulatory HLA class Ib molecules HLA-G and HLA-F, interacting with receptors on maternal immune cells. These molecules were found on extravillous trop...

Early Metabolomic Markers Can Predict Gestational Diabetes

Jul 25, 2022

Changes in pregnant women's blood were found in metabolites from early to mid-pregnancy that were linked with the risk for gestational diabetes in later pregnancy. “Gestational diabetes is ty...

Women's AMH Levels Can be Attributed to Three Distinct Genes

Jun 23, 2022

Ovarian follicles expressed AMH in the antral stage of development in females, and variation in age-specific circulating AMH levels was linked to illness outcomes. However, the physiological processes...

Randomized Clinical Research Demonstrates that High-Intensity Exercise Improves Cardiometabolic & Reproductive Outcomes More than Moderate-Intensity Training in Women With the Polycystic Ovarian Syndrome

Jun 23, 2022

It was established that exercise training improved clinical outcomes in women with PCOS, but it was unknown whether HIIT results in better health outcomes than traditional MICT.  Researchers conducte...

Human Sperm Cells Can Produce Paracetamol Metabolite AM404

Jun 23, 2022

According to studies, adult men with high urine levels of the over-the-counter mild painkiller APAP had decreased sperm mobility and a longer time to conception. The study included an in vivo human ph...

Clinical Prediction Model for Predicting the Chance of Successful Medical Treatment of Early Pregnancy Loss

Jun 23, 2022

The success rates of medicinal treatments for EPL were highly variable, both between and within therapy regimens. Although certain predictors were established up to this point, no clinical prediction ...

Cervical Ripening of Synthetic Osmotic Cervical Dilator

Jun 14, 2022

For a study, researchers sought to determine if a synthetic osmotic cervical dilator was as effective as oral misoprostol for cervical ripening. Pregnant women having induction of labor at 37 weeks or...

Fertility Preservation for Transgender Males

Jun 14, 2022

Multiple organizations, including the American Society for Reproductive Medicine, the World Professional Association for Transgender Health, and the Endocrine Society, supported fertility preservation...

Intrapartum Fetal Heart Rate Patterns Unassociated With Recognized Sentinel Events

Jun 14, 2022

The evolution of continuous electronic fetal heart rate (FHR) monitoring has presented the obstetrician with a critical clinical conundrum: basic science observations suggested that such monitoring ma...

Patterns of Sexual Activity & the Development of Sexual Pain

Jun 14, 2022

For a study, researchers sought to investigate whether patterns of sexual intercourse frequency and demographic, menopausal status, genitourinary, health, and psychosocial variables were linked to the...

Medicaid Expansion Under the Affordable Care Act

Jun 14, 2022

The 2014 Medicaid expansion under the Affordable Care Act (ACA) is connected with improvements in insurance and early-stage diagnosis among individuals with gynecologic cancer, but its relationship wi...

Mifepristone and Misoprostol Abortion Product

Jun 14, 2022

For a study, researchers sought to create a drug facts label prototype for a mifepristone and misoprostol combination product and perform label comprehension research to evaluate knowledge of key labe...

Menopausal Hormone Therapy Formulation & Breast Cancer Risk

Jun 14, 2022

For a study, researchers sought to determine if the formulation of menopausal hormone treatment (HT) utilized affected the increased risk of breast cancer. Using data from the UK Clinical Practice Res...

Clindamycin 2% Bioadhesive Gel for Bacterial Vaginosis

Jun 14, 2022

For a study, researchers sought to evaluate the effectiveness and safety of a single-dose vaginal clindamycin gel for treating bacterial vaginosis. They conducted a randomized, double-blind, placebo-c...

Postoperative Hormonal Suppression Effects on Fertility in Patients

Jun 13, 2022

For a study, researchers sought to assess the effect of hormone suppression on fertility in infertile individuals or patients trying to conceive following endometriosis surgery. Two independent review...

Delivery of Twins With Growth Discordance & Growth Restriction

Jun 13, 2022

First, the risks of stillbirth and neonatal mortality in twin pregnancies with varying levels of development discordance and connection to small for gestational age (SGA) were assessed, and ideal gest...

Care Levels for Fetal Therapy Centers

Jun 13, 2022

Fetal treatments used to improve fetal outcome or maximize newborn life frequently include some amount of maternal, fetal, or neonatal risk. Therefore, a fetal treatment facility must have access to r...

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