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OB/GYN General

Uterine Leiomyoma Cure With Relugolix Combination Therapy

Jun 13, 2022

For a study, researchers sought to evaluate once-daily relugolix combination treatment (relugolix-CT: relugolix 40 mg, estradiol 1 mg, and norethindrone acetate 0.5 mg) to placebo in women with uterin...

Hospitals' Performance for Severe Maternal Morbidity

Jun 13, 2022

For a study, researchers sought to determine which organizational variables, policies, and practices separate hospitals with high risk-adjusted rates of severe maternal morbidity (SMM) from those with...

Pregnant Women With Pregestational Diabetes

Jun 13, 2022

For a study, researchers sought to examine the relationship between community-level social vulnerability and establishing glycemic control (defined as Hb A1c less than 6.0% or less than 6.5%) in peopl...

Azithromycin Dosage: Cesarean Delivery & Postnatal Infection

Jun 13, 2022

For a study, researchers sought to determine the relationship between the timing of the administration of adjunctive azithromycin for prophylaxis during an unplanned cesarean birth and maternal infect...

SARS-CoV-2 Seropositivity in Pregnancy: Neighborhood Characteristics & Racial Disparities

Jun 13, 2022

For a study, researchers sought to determine the extent to which neighborhood variables contribute to racial and ethnic inequalities in SARS coronavirus 2 (SARS-CoV-2) seropositivity in pregnancy. Fro...

Risk of Deliveries and Pregnancy Outcomes for Patients

Jun 13, 2022

For a study, researchers sought to describe the trends in delivery hospitalization among patients aged 11–19 years, as well as the related comorbidities and outcomes. Deliveries to patients aged 11...

Transvaginal Mesh Compared With Native Tissue Repair

Jun 13, 2022

In response to a U.S. Food and Drug Administration (FDA) 522 study to test co-primary endpoints of superiority and noninferiority, researchers compared the safety and efficacy of transvaginal mesh rep...

Sparking Positive Dialogue in Women & Men With Obesity

Jun 06, 2022

While obesity is a chronic, complex disease that can affect anyone, it impacts men and women differently. Although the proportion of men and women with excess weight is about equal, the severity is di...

Introduction of salvage prostatectomy in Denmark: the initial experience.

May 23, 2022

To introduce salvage prostatectomy in Denmark. Prior to this, no national curative treatment for recurrent prostate cancer following radiation therapy existed in Denmark. This pilot study represent ou...

Splenic artery aneurysm in pregnancy: a systematic review.

May 23, 2022

Splenic artery aneurysms (SAA) are associated with significant maternal and fetal mortality when ruptured in pregnancy. However, there is no consensus on the optimal obstetric management of both ruptu...

A prodrug of 3-(ferrocenylaminocarbonyloxymethyl)phenol activated by reactive oxygen species in cancer cells.

May 23, 2022

Hybrid drugs containing ferrocene and phenol residues, whose π systems are not conjugated with each other, exhibit potent anticancer activity as previously reported. Few important open questions are ...

Preoperative application of the Enzian classification for endometriosis (The cEnzian Study): a prospective international multicenter study.

May 23, 2022

To assess the diagnostic performance of preoperative application of the Enzian classification (cEnzian) using surgical findings as reference standard DESIGN: A prospective international non-interventi...

Archimetrosis: the evolution of a disease and its extant presentation : Pathogenesis and pathophysiology of archimetrosis (uterine adenomyosis and endometriosis).

May 23, 2022

This article presents a novel concept of the evolution and, thus, the pathogenesis of uterine adenomyosis as well as peritoneal and peripheral endometriosis. Presently, no unifying denomination of thi...

Targeting epidermal growth factor receptor in paclitaxel-resistant human breast and lung cancer cells with upregulated glucose-6-phosphate dehydrogenase.

May 23, 2022

Chemoresistance is a major obstacle to the successful treatment of triple-negative breast cancer (TNBC) and non-small-cell lung cancer (NSCLC). Therapeutic strategies to overcome chemoresistance are n...

Patient navigator team perceptions on the implementation of a citywide breast cancer patient navigation protocol: a qualitative study.

May 23, 2022

In 2018 Translating Research Into Practice (TRIP), an evidence-based patient navigation intervention aimed at addressing breast cancer care disparities, was implemented across six Boston hospitals. Th...

Hands-on Simulation Workshop for Obstetric Ultrasound-Guided Invasive Procedures.

May 23, 2022

Due to the introduction of cell-free DNA genetic testing options, the number of clinical ultrasound procedures has greatly diminished in recent years. With fewer real-life ultrasound-guided procedures...

Sexual Function Following Treatment for Stress Urinary Incontinence With Bulk Injection Therapy and Mid-Urethral Sling Surgery.

May 16, 2022

Peri-urethral bulking injections (PBI) gain popularity for the treatment of stress urinary incontinence (SUI), but - in contrast to mid-urethral sling (MUS) surgery - little is known about its impact ...

Association between use of ERAS protocols and complications after radical cystectomy.

May 16, 2022

Implementation of enhanced recovery protocols in cystectomy patients has significantly changed the perioperative course of this major operation. This paper summarizes evidence based interventions to e...

Developing guideline-based key performance indicators for recurrent miscarriage care: lessons from a multi-stage consensus process with a diverse stakeholder group.

May 16, 2022

Standardised care pathways tailored to women/couples who experience recurrent miscarriage are needed; however, clinical practice is inconsistent and poorly organised. In this paper, we outline our pro...

The enhancer RNA ADCY10P1 is associated with the progression of ovarian cancer.

May 16, 2022

Emerging evidence identifies enhancer RNAs (eRNAs) as a class of regulatory ncRNAs that can contribute to the transcription of target genes. In this study, we used an integrated data analysis method t...

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