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OB/GYN General

Introduction of salvage prostatectomy in Denmark: the initial experience.

May 23, 2022

To introduce salvage prostatectomy in Denmark. Prior to this, no national curative treatment for recurrent prostate cancer following radiation therapy existed in Denmark. This pilot study represent ou...

Splenic artery aneurysm in pregnancy: a systematic review.

May 23, 2022

Splenic artery aneurysms (SAA) are associated with significant maternal and fetal mortality when ruptured in pregnancy. However, there is no consensus on the optimal obstetric management of both ruptu...

A prodrug of 3-(ferrocenylaminocarbonyloxymethyl)phenol activated by reactive oxygen species in cancer cells.

May 23, 2022

Hybrid drugs containing ferrocene and phenol residues, whose π systems are not conjugated with each other, exhibit potent anticancer activity as previously reported. Few important open questions are ...

Preoperative application of the Enzian classification for endometriosis (The cEnzian Study): a prospective international multicenter study.

May 23, 2022

To assess the diagnostic performance of preoperative application of the Enzian classification (cEnzian) using surgical findings as reference standard DESIGN: A prospective international non-interventi...

Archimetrosis: the evolution of a disease and its extant presentation : Pathogenesis and pathophysiology of archimetrosis (uterine adenomyosis and endometriosis).

May 23, 2022

This article presents a novel concept of the evolution and, thus, the pathogenesis of uterine adenomyosis as well as peritoneal and peripheral endometriosis. Presently, no unifying denomination of thi...

Targeting epidermal growth factor receptor in paclitaxel-resistant human breast and lung cancer cells with upregulated glucose-6-phosphate dehydrogenase.

May 23, 2022

Chemoresistance is a major obstacle to the successful treatment of triple-negative breast cancer (TNBC) and non-small-cell lung cancer (NSCLC). Therapeutic strategies to overcome chemoresistance are n...

Patient navigator team perceptions on the implementation of a citywide breast cancer patient navigation protocol: a qualitative study.

May 23, 2022

In 2018 Translating Research Into Practice (TRIP), an evidence-based patient navigation intervention aimed at addressing breast cancer care disparities, was implemented across six Boston hospitals. Th...

Hands-on Simulation Workshop for Obstetric Ultrasound-Guided Invasive Procedures.

May 23, 2022

Due to the introduction of cell-free DNA genetic testing options, the number of clinical ultrasound procedures has greatly diminished in recent years. With fewer real-life ultrasound-guided procedures...

Sexual Function Following Treatment for Stress Urinary Incontinence With Bulk Injection Therapy and Mid-Urethral Sling Surgery.

May 16, 2022

Peri-urethral bulking injections (PBI) gain popularity for the treatment of stress urinary incontinence (SUI), but - in contrast to mid-urethral sling (MUS) surgery - little is known about its impact ...

Association between use of ERAS protocols and complications after radical cystectomy.

May 16, 2022

Implementation of enhanced recovery protocols in cystectomy patients has significantly changed the perioperative course of this major operation. This paper summarizes evidence based interventions to e...

Developing guideline-based key performance indicators for recurrent miscarriage care: lessons from a multi-stage consensus process with a diverse stakeholder group.

May 16, 2022

Standardised care pathways tailored to women/couples who experience recurrent miscarriage are needed; however, clinical practice is inconsistent and poorly organised. In this paper, we outline our pro...

The enhancer RNA ADCY10P1 is associated with the progression of ovarian cancer.

May 16, 2022

Emerging evidence identifies enhancer RNAs (eRNAs) as a class of regulatory ncRNAs that can contribute to the transcription of target genes. In this study, we used an integrated data analysis method t...

Embryo morphological quality in relation to the metabolic and cognitive development of singletons conceived by in vitro fertilization/intracytoplasmic sperm injection: A matched cohort study.

May 16, 2022

Embryos with higher morphological quality may have a greater potential to achieve clinical pregnancy leading to live birth regardless of the type of cleavage-stage embryos or blastocysts. Few studies ...

Pre-analytical processing protocol of breast biopsies affects multigene panel results.

May 16, 2022

The creation of multigene panels for prognostic and predictive purposes allows a more accurate indication of adjuvant chemotherapy for patients with breast cancer. In a previous study, we reproduced a...

Having Heart: Affective and Cognitive Empathy Scores vs. Residency Specialty Match at an Osteopathic Medical School.

May 16, 2022

Past studies examining the cognitive empathy of medical school graduates grouped the various residency selections vs. parsing them out. This study examines both affective and cognitive empathy scores ...

Male Contraception is Coming: Who Do Men Want to Prescribe their Birth Control?

May 16, 2022

To assess men's preferences for type of healthcare provider from whom they would obtain hormonal male contraceptive (HMC) methods.We asked participants from three clinical trials of investigational ho...

Sacral Neuromodulation Using a Novel Device with a Six-contact-point Electrode for the Treatment of Patients with Refractory Overactive Bladder: A Multicenter, Randomized, Single-blind, Parallel-control Clinical Trial.

May 09, 2022

A novel sacral neuromodulation system (SacralStim) which has an electrode with six contact points was recently designed.To evaluate the effectiveness and safety of the SacralStim system for treating p...

Patterns of contraceptive use among young Australian women with chronic disease: findings from a prospective cohort study.

May 09, 2022

Given chronic disease is increasing among young women and unintended pregnancies among these women are associated with poor maternal and fetal outcomes, these women would benefit from effective precon...

LncRNA LINC00665 Promotes Ovarian Cancer Cell Proliferation and Inhibits Apoptosis via Targeting miR-181a-5p/FHDC.

May 09, 2022

Previous reports indicate that long intergenic non-coding RNA LINC00665 naturally occurred vital effects in various cancers. Herein, the role of LINC00665 in ovarian cancer progress was explored. We f...

FBXO2 targets glycosylated SUN2 for ubiquitination and degradation to promote ovarian cancer development.

May 09, 2022

SAD1/UNC84 domain protein-2 (SUN2) plays a tumor suppressor role in various types of cancer by inhibiting cancer cell proliferation, migration and promoting apoptosis. However, the post-translational ...

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