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OB/GYN General

Presence of adenomyosis at MRI reduces live birth rates in ART cycles for endometriosis.

Apr 25, 2022

What is the impact of adenomyosis on the live birth rate (LBR) in women affected by endometriosis women undergoing ART?For women undergoing ART, the presence of adenomyosis at MRI, especially T2 high-...

Long noncoding RNA KB-1980E6.3 promotes breast cancer progression through the PI3K/AKT signalling pathway.

Apr 25, 2022

This research aims to investigate the effect of lncRNA KB-1980E6.3 on the biological behaviour of breast cancer cells under normoxic conditions and the underlying molecular mechanism. The expression o...

The Modulatory Effect of Adipose-Derived Stem Cells on Endometrial Polyp Fibroblasts.

Apr 25, 2022

Endometrial polyps (EPs) are benign overgrowths of the endometrium, with the potential to cause severe complications, ranging from discomfort to inflammation and infertility. Dysfunction of endometria...

Compounds Enhancing Human Sperm Motility Identified Using a HTS Platform

Apr 18, 2022

There were several attempts to uncover tiny compounds that modulate sperm activity, but none have used high-throughput technologies. Semen samples from healthy donors were used, and samples were poole...

Metabolic State of Human Blastocysts Measured By Fluorescence Lifetime Imaging Microscopy (FLIM)

Apr 18, 2022

Embryo metabolism was connected to viability, implying that it could be helpful to in ART to aid in the selection of high-quality embryos. However, due to a lack of non-invasive technologies for measu...

Endometrial Gene Expression Related to Cilia & Aging

Apr 18, 2022

Endometrial transcriptome data from the Gene Expression Omnibus (GEO) sample repository was analyzed retrospectively in silico for 27 women of various aging. An independent gene expression dataset of ...

EndoTime: Luteal Endometrial Non-Categorical Timing Estimations

Apr 18, 2022

Endometrial timing methods based on gene expression that were commercially accessible required large gene sets and used a categorical approach that categorized samples as pre-receptive, receptive, or ...

Emulating a Target Trial to Compare the Efficacy of Clomiphene Citrate & Letrozole For Ovulation Induction

Apr 18, 2022

For a study, researchers sought to create a simulation of a hypothetical trial comparing the efficacy of letrozole against clomiphene citrate for ovulation induction in all women, then stratified by P...

Single-stage repair for female epispadias with urinary incontinence: A case report and literature review.

Apr 18, 2022

Epispadias is a rare condition. Epispadias in females is two times less common than in males. Female epispadias range from 1 in 160,000 to 480,000 live births. Epispadias can be diagnosed through care...

An effective AKT inhibitor-PARP inhibitor combination therapy for recurrent ovarian cancer.

Apr 18, 2022

Although the use of PARP inhibitor has received considerable amount of attention in ovarian cancer, PARP inhibitor resistance still emerges with disease progression. PI3K/AKT pathway inhibitors have b...

Accuracy of transvaginal ultrasound and magnetic resonance imaging for diagnosis of deep endometriosis in bladder and ureter: a meta-analysis.

Apr 18, 2022

This meta-analysis aimed to determine the accuracy of transvaginal ultrasound (TVS) and pelvic magnetic resonance imaging (MRI) in diagnosing urinary tract endometriosis (UTE). A comprehensive search ...

Facile fabrication of hypercrosslinked microporous polymer nanospheres for effective inhibition of triple negative breast cancer cells proliferation.

Apr 18, 2022

Treatment failure is one of the main lethal causes of human triple negative breast cancer (TNBC) patients due to inefficient drug administration. The present study demonstrated the development of func...

Smartly responsive DNA-miRNA hybrids packaged in exosomes for synergistic enhancement of cancer cell apoptosis.

Apr 18, 2022

Endogenous and exogenous tumor-related microRNAs (miRNAs) are considered promising tumor biomarkers and tumor therapeutic agents. In this work, we propose a miRNA self-responsive drug delivery system ...

Salubrious effects of ulinastatin and quercetin alone or in combination in endothelial dysfunction and vascular dementia.

Apr 11, 2022

Vascular dementia is the second most prevalent form of dementia. Hypertension is the leading risk factor for endothelial dysfunction and the progression of dementia that is of vascular origin. This st...

Long-term outcomes of whole gland high-intensity focused ultrasound for localized prostate cancer.

Apr 11, 2022

To report the 10-year oncologic and functional outcomes of whole-gland HIFU as first-line treatment for localized prostate cancer (PCa).Patients were retrospectively included between January 2005 and ...

Basic and applied features in the cryopreservation progress of bovine embryos.

Apr 11, 2022

The expansion of the use of in vitro production techniques has revolutionized the bovine embryo market. In the last decade, we have seen the number of in vitro produced (IVP) embryos surpass the numbe...

Ovarian Cancer Ascites Inhibits Transcriptional Activation of NK Cells Partly through CA125.

Apr 11, 2022

Malignant ascites is a common clinical problem in ovarian cancer. NK cells are present in the ascites, but their antitumor activity is inhibited. The underlying mechanisms of the inhibition have yet t...

Updated meta-analysis on the diagnostic accuracy of serum anti-Mullerian hormone in poly cystic ovary syndrome involving 13 509 subjects.

Apr 11, 2022

To determine the diagnostic accuracy of anti-Mullerian hormone (AMH) in the diagnosis of polycystic ovary syndrome (PCOS).Two independent reviewers searched the electronic databases and search engines...

Negative associations of ideal family size achievement with hypertension, obesity and maternal age in women with and without polycystic ovary syndrome.

Apr 11, 2022

To investigate lifetime reproductive outcomes and the relationship of ideal family size (IFS) achievement with metabolic, psychiatric and reproductive history in women with and without polycystic ovar...

The role of percutaneous vertebral augmentation in patients with metastatic breast cancer: Literature review including report of two cases.

Apr 11, 2022

Patients with metastatic breast cancer are at high risk for developing vertebral compression fractures due to underlying bone metastases and bone density loss. Vertebral augmentation techniques includ...

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