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OB/GYN General

Nomogram for predicting the long-term outcomes of uterine artery embolization for adenomyosis.

Feb 07, 2022

The present study aimed to develop a nomogram to predict long-term outcomes of uterine artery embolisation (UAE) for treating adenomyosis.We reviewed data of 221 patients with adenomyosis who underwen...

Increase in ADAR1p110 activates the canonical Wnt signaling pathway associated with aggressive phenotype in triple negative breast cancer cells.

Feb 07, 2022

Triple-negative breast cancer (TNBC) represents a challenge in the search for new therapeutic targets. TNBCs are aggressive and generate resistance to chemotherapy. Tumors of TNBC patients with poor p...

Topoisomerase IIα inhibitory and antiproliferative activity of dihydroxylated 2,6-diphenyl-4-fluorophenylpyridines: Design, synthesis, and structure-activity relationships.

Feb 07, 2022

A new series of fifty-four 2-phenol-4-aryl-6-hydroxyphenylpyridines containing fluorophenyl, trifluoromethylphenyl, and trifluoromethoxy phenyl groups were synthesized and tested for topoisomerase IIÎ...

Medium term anatomical and functional outcomes following modified laparoscopic sacrocolpopexy.

Jan 31, 2022

We evaluated the anatomical and functional outcomes following modified laparoscopic sacrocolpopexy (LSC) utilizing deep dissection of the vaginal walls and distal mesh fixation at the anterior and pos...

The Development of F Fluorthanatrace: A PET Radiotracer for Imaging Poly (ADP-Ribose) Polymerase-1.

Jan 31, 2022

Fluorine 18 (F) fluorthanatrace (F-FTT) is a PET radiotracer for imaging poly (adenosine diphosphate-ribose) polymerase-1 (PARP-1), an important target for a class of drugs known as PARP inhibitors, o...

The clinical effectiveness and safety of traditional Chinese medicine Jinfeng pill in adjuvant treatment of infertility with polycystic ovary syndrome: A protocol for systematic review and meta-analysis.

Jan 31, 2022

Polycystic ovary syndrome (PCOS) is the main cause of infertility in women, the essence of which is an endocrine disorder syndrome with abnormal sugar metabolism and reproductive dysfunction, and the ...

Disruption of the pentraxin 3/CD44 interaction as an efficient therapy for triple-negative breast cancers.

Jan 31, 2022

Due to the heterogeneity and high frequency of genome mutations in cancer cells, targeting vital protumour factors found in stromal cells in the tumour microenvironment may represent an ideal strategy...

Protein phosphatase 1 regulatory inhibitor subunit 14C promotes triple-negative breast cancer progression via sustaining inactive glycogen synthase kinase 3 beta.

Jan 31, 2022

Triple-negative breast cancer (TNBC) is fast-growing and highly metastatic with the poorest prognosis among the breast cancer subtypes. Inactivation of glycogen synthase kinase 3 beta (GSK3β) plays a...

Professionalism in Family Planning Care Workshop.

Jan 31, 2022

When clinicians feel negative emotions toward patients, providinge patient-centered care can be difficult. This can occur in family planning scenarios, such as when a provider is uncomfortable with a ...

Gynaecologic Surgery Prophylactic Negative Pressure Wound Therapy After Laparotomy

Jan 25, 2022

For a study, researchers wanted to determine the efficacy of preventive negative pressure wound treatment in patients having laparotomy for gynecologic surgery. Researchers carried out a randomized co...

Obstetricians' Attitudes and Knowledge of Guidelines and Screening Tools to Reduce Opioid Use Following Childbirth

Jan 25, 2022

For a study, researchers wanted to investigate obstetricians' attitudes on adopting professional or regulatory guidelines, opioid risk-screening instruments, and recommendations for nonanalgesic thera...

Vital Sign Reference Ranges for Postpartum Women

Jan 25, 2022

Researchers wanted to estimate typical postpartum mother vital sign ranges for a study. They conducted a multicenter prospective longitudinal cohort research. They looked for women who were less than ...

Long-term Clinical Outcomes of Major Adverse Vascular Events Following Pregnancy Hypertensive Disorders

Jan 25, 2022

For a study, researchers wanted to investigate the relationship between hypertensive diseases of pregnancy and unfavorable postpartum outcomes, such as chronic kidney disease and serious adverse cardi...

Severe Maternal Morbidity and the Risk of Mortality After Childbirth

Jan 25, 2022

Researchers wanted to investigate the long-term risks of death following a pregnancy complicated by significant maternal morbidity. Researchers examined a longitudinal cohort of 1,229,306 women who ga...

In a Canadian Population, Changes in the Frequency of Caesarean Delivery in Nulliparous Women in Labour

Jan 25, 2022

For a study, researchers wanted to determine the relative influence of changes in patient demographics and physician management to changes in the cesarean delivery rate in labor among nulliparous wome...

The Relationship Between Persistent Breech Presentation and External Cephalic Version Success

Jan 25, 2022

For a study, researchers wanted to assess the possibility of a link between a novel variable, persistent breech presentation, and the success rate of the external cephalic version (ECV). This was a re...

Expectant Management of Full-Term, Low-Risk, Nulliparous Patients: Maternal and Perinatal Outcomes

Jan 25, 2022

For a study, researchers wanted to examine the risks of maternal and perinatal outcomes in low-risk nulliparous patients undergoing expectant care based on the completed week of gestation from 39 week...

The Dallas Uterus Transplant Study Has Twelve Live Births After Uterus Transplantation

Jan 25, 2022

For a study, researchers described aggregated pregnancy outcomes following uterine transplantation at a single experienced facility. The prospective research reported on live births among 20 women who...

Treatment Algorithm for Severe Hypertension in Pregnancy that is Semiautonomous

Jan 25, 2022

For a study, researchers wanted to determine if the deployment of a semiautonomous treatment algorithm was linked with increased compliance with the American College of Obstetricians and Gynecologists...

After Vaginal Delivery, Postpartum Salpingectomy vs. Standard Tubal Ligation

Jan 25, 2022

For a study, researchers wanted to compare the surgical results of postpartum salpingectomy and tubal ligation following vaginal birth. Using the electronic medical record, the retrospective cohort an...

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