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OB/GYN General

European Expert Consensus on Practical Management of Specific Aspects of Parathyroid Disorders in Adults and in Pregnancy: Recommendations of the ESE Educational Program of Parathyroid Disorders.

Dec 06, 2021

This European expert consensus statement provides recommendations for the diagnosis and management of primary hyperparathyroidism (PHPT), chronic hypoparathyroidism in adults (HypoPT), and parathyroid...

Menstrual factors, reproductive history, and risk of lung cancer: a multi-center population-based cohort study in Chinese females.

Dec 06, 2021

Female menstrual and reproductive factors, as remarkable indicators of hormone effect, were hypothesized to be associated with lung cancer risk, whereas the existed epidemiological evidence was incons...

A conceptual model of vulnerability to care delay among women at risk for uterine cancer.

Dec 06, 2021

Care delay may allow for cancer progression prior to treatment initiation. However, in endometrial cancer, quantitative data to support this hypothesis is mixed. Factors that cuase delay prior to clin...

Lapses in breast cancer screening for highly penetrant mutation carriers during pregnancy and lactation.

Dec 06, 2021

Screening for breast cancer in highly penetrant mutation carriers during pregnancy and lactation is challenging and consensus guidelines are lacking. This study evaluates the lapse in screening and th...

Postpartum anhedonia: Emergent patterns in bipolar and unipolar depression.

Nov 29, 2021

The objective of this study was to identify differences in the longitudinal course anhedonia symptoms during postpartum in women diagnosed with unipolar or bipolar disorder. Female participants diagno...

Curcumin derivative ST09 modulates the miR-199a-5p/DDR1 axis and regulates proliferation and migration in ovarian cancer cells.

Nov 29, 2021

Ovarian cancers are among the fatal malignancies affecting women globally, mainly due to their metastatic and chemoresistant nature. In this study, we report a potent curcumin derivative ST09 effectiv...

Multispectral label-free Raman spectroscopy can detect gynecologic cancer with high accuracy.

Nov 29, 2021

Up to 70% of ovarian cancer patients are diagnosed with advanced-stage disease and the degree of cytoreduction is an important survival prognostic factor. The aim of this study was to evaluate if Rama...

Extremely high anti-Mullerian hormone levels detected during infertility workup revealing sex cord tumor with annular tubules and underlying Peutz-Jeghers syndrome: A case report.

Nov 29, 2021

We report an infertile, but otherwise asymptomatic woman, whose extremely high anti-Mullerian hormone (AMH) level detected during infertility investigation led to the diagnosis of sex cord tumor with ...

Genomic mutation features identify distinct BRCA-associated mutation characteristics in endometrioid carcinoma and endometrioid ovarian carcinoma.

Nov 29, 2021

Although endometrioid carcinoma (EC) and endometrioid ovarian carcinoma (EnOC) display similar pathological features, their molecular characteristics remain to be determined. Somatic mutation data fro...

Label-free isolation and cultivation of patient-matched human mammary epithelial and stromal cells from normal breast tissue.

Nov 29, 2021

Breast cancer is primarily derived from mammary epithelial cells, the main cell type in human mammary glands. The majority of knowledge gained thus far around breast cancer has come from research usin...

Disparities in Complications After Prolapse Repair and Sling Procedures: Trends from 2010-2018.

Nov 22, 2021

To compare 30-day complication rates after prolapse repair and sling procedures across racial/ethnic groups, and evaluate trends over time.We identified female patients in a national outcomes-based da...

"Potential entry receptors for human γ-herpesvirus into epithelial cells: a plausible therapeutic target for viral infections".

Nov 22, 2021

Herpesviruses are ubiquitous viruses, specifically the Epstein Barr virus (EBV). EBV and Kaposi's sarcoma-associated herpesvirus (KSHV) establish their latency for a long period in B-cells and their r...

[Retrospective validation of a model to predict the outcome of pregnancies of unknown location].

Nov 22, 2021

The prediction model M6 classifies pregnancy of unknown location (PUL) into a lor-risk or a high-risk group in developing ectopic pregnancy (EP). The aim of this study was to validate the two step M6 ...

'A small person that we made' - Parental conceptualisation of the unborn child: A constructivist grounded theory.

Nov 22, 2021

The way that expectant parents think and feel about the fetus during pregnancy is thought to be somewhat predictive of their later relationship with the child. However, efforts to identify determinant...

Liquid biopsy for ovarian cancer using circulating tumor cells: Recent advances on the path to precision medicine.

Nov 22, 2021

Ovarian cancer (OC) is the most lethal gynecologic malignance worldwide. Considering its metastasis nature, oncologists shift focus towards circulating tumor cells (CTCs), a progenitor that originates...

Lifetime caffeine intake and the risk of epithelial ovarian cancer.

Nov 22, 2021

Caffeine intake has been inconsistently associated with the risk of ovarian cancer in previous studies. The measure of caffeine in these studies has not always distinguished between caffeinated and de...

A method of separating extracellular vesicles from blood shows potential clinical translation, and reveals extracellular vesicle cargo gremlin-1 as a diagnostic biomarker.

Nov 22, 2021

Extracellular vesicles (EVs) have potential as minimally invasive biomarkers. However, the methods most commonly used for EV retrieval rely on ultracentrifugation, are time-consuming, and unrealistic ...

Tetrahedral DNA nanostructure based biosensor for high-performance detection of circulating tumor DNA using all-carbon nanotube transistor.

Nov 22, 2021

Adopting carbon nanotube (CNT) transistors as biosensors has been developed as a promising method for cancer biomarker detection, which has shown superior sensitivity and selectivity. However, the det...

Pipelle endometrial biopsy for abnormal uterine bleeding: do patient's pain and anxiety really impact on sampling success rate?

Nov 22, 2021

Pipelle endometrial biopsy is vital for the early diagnostics of endometrial pathology and is performed in outpatient setting in minimally invasive manner. One of the reported disadvantages of samplin...

Racial and Ethnic Disparities in Death

Nov 18, 2021

To describe temporal patterns in racial and ethnic differences in failure to rescue linked with severe maternal morbidity. This was cohort research that used administrative data to do retrospective an...

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