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OB/GYN General

Genomic mutation features identify distinct BRCA-associated mutation characteristics in endometrioid carcinoma and endometrioid ovarian carcinoma.

Nov 29, 2021

Although endometrioid carcinoma (EC) and endometrioid ovarian carcinoma (EnOC) display similar pathological features, their molecular characteristics remain to be determined. Somatic mutation data fro...

Label-free isolation and cultivation of patient-matched human mammary epithelial and stromal cells from normal breast tissue.

Nov 29, 2021

Breast cancer is primarily derived from mammary epithelial cells, the main cell type in human mammary glands. The majority of knowledge gained thus far around breast cancer has come from research usin...

Disparities in Complications After Prolapse Repair and Sling Procedures: Trends from 2010-2018.

Nov 22, 2021

To compare 30-day complication rates after prolapse repair and sling procedures across racial/ethnic groups, and evaluate trends over time.We identified female patients in a national outcomes-based da...

"Potential entry receptors for human γ-herpesvirus into epithelial cells: a plausible therapeutic target for viral infections".

Nov 22, 2021

Herpesviruses are ubiquitous viruses, specifically the Epstein Barr virus (EBV). EBV and Kaposi's sarcoma-associated herpesvirus (KSHV) establish their latency for a long period in B-cells and their r...

[Retrospective validation of a model to predict the outcome of pregnancies of unknown location].

Nov 22, 2021

The prediction model M6 classifies pregnancy of unknown location (PUL) into a lor-risk or a high-risk group in developing ectopic pregnancy (EP). The aim of this study was to validate the two step M6 ...

'A small person that we made' - Parental conceptualisation of the unborn child: A constructivist grounded theory.

Nov 22, 2021

The way that expectant parents think and feel about the fetus during pregnancy is thought to be somewhat predictive of their later relationship with the child. However, efforts to identify determinant...

Liquid biopsy for ovarian cancer using circulating tumor cells: Recent advances on the path to precision medicine.

Nov 22, 2021

Ovarian cancer (OC) is the most lethal gynecologic malignance worldwide. Considering its metastasis nature, oncologists shift focus towards circulating tumor cells (CTCs), a progenitor that originates...

Lifetime caffeine intake and the risk of epithelial ovarian cancer.

Nov 22, 2021

Caffeine intake has been inconsistently associated with the risk of ovarian cancer in previous studies. The measure of caffeine in these studies has not always distinguished between caffeinated and de...

A method of separating extracellular vesicles from blood shows potential clinical translation, and reveals extracellular vesicle cargo gremlin-1 as a diagnostic biomarker.

Nov 22, 2021

Extracellular vesicles (EVs) have potential as minimally invasive biomarkers. However, the methods most commonly used for EV retrieval rely on ultracentrifugation, are time-consuming, and unrealistic ...

Tetrahedral DNA nanostructure based biosensor for high-performance detection of circulating tumor DNA using all-carbon nanotube transistor.

Nov 22, 2021

Adopting carbon nanotube (CNT) transistors as biosensors has been developed as a promising method for cancer biomarker detection, which has shown superior sensitivity and selectivity. However, the det...

Pipelle endometrial biopsy for abnormal uterine bleeding: do patient's pain and anxiety really impact on sampling success rate?

Nov 22, 2021

Pipelle endometrial biopsy is vital for the early diagnostics of endometrial pathology and is performed in outpatient setting in minimally invasive manner. One of the reported disadvantages of samplin...

Racial and Ethnic Disparities in Death

Nov 18, 2021

To describe temporal patterns in racial and ethnic differences in failure to rescue linked with severe maternal morbidity. This was cohort research that used administrative data to do retrospective an...

Health Care Use By Commercially Insured Postpartum And Nonpostpartum Women

Nov 17, 2021

The purpose of this study was to examine the types, frequency, and timing of health care use among commercially insured postpartum and nonpostpartum women. The data for this retrospective cohort analy...

Improved Recognition of Maternal Deaths Using Modern Data Analytics

Nov 17, 2021

Using a data-fusion technique to increase detection of maternal fatalities that are not discovered using regular monitoring tactics was the goal of this study. From 2011 to 2018, researchers conducted...

Rethinking Bias to Achieve Maternal Health Equity

Nov 17, 2021

This article discusses the limits of existing implicit bias treatments as an approach for attaining maternal health equity.  It then looks at how institutionalized racial stereotyping damages Black m...

Which children are at risk of developing overactive bladder in early adulthood even if lower urinary tract symptoms improve during childhood?

Nov 15, 2021

To evaluate more comprehensively the presence of an association between childhood lower urinary tract symptoms and development of adulthood overactive bladder, to determine the group at most risk of o...

The Risk of Preterm Birth in Low Risk Pregnant Women with Urinary Tract Infections.

Nov 15, 2021

 Urinary tract infections are among the most common infections during pregnancy. The association between symptomatic lower urinary tract infections during pregnancy and fetal and maternal complicati...

Molecular Characterization of Peritoneal Involvement in Primary Colon and Ovary Neoplasm: The Possible Clinical Meaning of the P2X7 Receptor-Inflammasome Complex.

Nov 15, 2021

Colon cancer (CC) and epithelial ovarian cancer (EOC) are common and severe neoplasms frequently sharing a massive inflammatory involvement of peritoneum. A detailed molecular characterization of such...

Longitudinal changes in employment following a diagnosis of endometriosis: Findings from an Australian cohort study.

Nov 15, 2021

Endometriosis is a chronic inflammatory disease affecting the reproductive, gastrointestinal and urinary systems. We examined changes in labour force participation among women with endometriosis follo...

Jewish Cultural and Religious factors and uptake of Population based BRCA testing across denominations: a cohort study.

Nov 15, 2021

To evaluate the association of Jewish cultural and religious identity and denominational affiliation with interest-in, intention-to undertake and uptake-of population-based BRCA (Breast Cancer Gene)-t...

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