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OB/GYN General

Prevention of Venous Thromboembolism in Gynecologic Surgery

Nov 02, 2021

Deep vein thrombosis (DVT) and pulmonary embolism (PE) are both examples of venous thromboembolic occurrences (VTE). Despite advancements in prevention, detection, and therapy, VTE continues to be a m...

Considerations And Recommendations for Pregnancy and Postpartum Care

Nov 02, 2021

Significant progress has been achieved in decreasing prenatal human immunodeficiency virus (HIV) transmission in the United States and across the world. Despite these advances, avoidable prenatal HIV ...

Term Pregnancy After Complete Response of Placental Site Trophoblastic Tumor to Immunotherapy

Nov 02, 2021

Hysterectomy is the standard therapy for placental location trophoblastic tumour. This may be unacceptable to women who want to have children. Cells that have gone awry in a placental site trophoblast...

A Training Simulator for Fractional Dilation and Curettage With Visualized Force-Position Feedback

Nov 02, 2021

Dilation and curettage (D&C) is a simple but significant operation used in obstetrics and gynaecology. Fractional D&C allows for thorough sampling of the endocervix and, later, the uterus. Thi...

Obliterated Posterior Cul-de-sac Laparoscopic Surgical Simulation

Nov 02, 2021

Obliteration of the posterior cul-de-sac is a difficult and frequently unexpected surgical finding. Developing the dissection skills necessary to manage this discovery during laparoscopy is critical f...

Adverse Birth Outcomes Associated With Prepregnancy and Prenatal Electronic Cigarette Use

Nov 02, 2021

The purpose of this study is to assess the risk of poor birth outcomes in individuals who use electronic cigarettes before and during pregnancy. Data from the 2016–2018 PRAMS were used to examine th...

Pregnancy Risk By Frequency And Timing of Unprotected Intercourse Before Intrauterine Device Placement

Nov 02, 2021

The number and timing of unprotected intercourse sessions in the previous 14 days were used to estimate pregnancy risk following IUD insertion. This was a secondary analysis of a randomised study that...

Nifedipine for Acute Tocolysis of Preterm Labor

Nov 02, 2021

The purpose of this study was to see how efficient acute nifedipine tocolysis was at preventing premature delivery in women in preterm labour. This was a randomised, double-blind, placebo-controlled s...

Obstetrician–Gynecologists' Practices in Postpartum Sterilization

Nov 02, 2021

To investigate obstetrician–gynecologists' practises in the United States regarding postpartum sterilisation where the Medicaid permission form was not legitimate was the study’s goal. Using the A...

Two-Layer Compared With One-Layer Vaginal Cuff Closure

Nov 02, 2021

The purpose of this study is to see if two-layer laparoscopic vaginal cuff closure during laparoscopic hysterectomy is linked with a reduced risk of postoperative problems than a normal one-layer cuff...

Cognitive-behavioral therapy and urge urinary incontinence in women. A systematic review.

Nov 01, 2021

UUI co-exists with numerous health conditions, having a substantial negative impact on health-related quality of life and mental health. Cognitive-behavioral therapy (CBT) could help patients manage t...

Neurovascular structure-adjacent frozen-section examination robotic-assisted radical prostatectomy: outcomes from 500 consecutive cases in the UK.

Nov 01, 2021

The purpose is to report the United Kingdom's largest single-centre experience of robotically assisted laparoscopic radical prostatectomies (RALP), using the neurovascular structure-adjacent frozen-se...

1-Nitropyrene exposure impairs embryo implantation through disrupting endometrial receptivity genes expression and producing excessive ROS.

Nov 01, 2021

Haze problem is an important factor threatening human health. PM2.5 is the main culprit haze. 1-Nitropyrene (1-NP) is the main nitrated polycyclic aromatic hydrocarbon, the toxic component of PM2.5 pa...

Efficacy and safety of standard of care with/without bevacizumab for platinum-resistant ovarian/fallopian tube/peritoneal cancer previously treated with bevacizumab: the Japanese Gynecologic Oncology Group study JGOG3023.

Nov 01, 2021

We investigated the efficacy and safety of further bevacizumab therapy in platinum-resistant ovarian cancer patients whose disease had progressed after bevacizumab plus chemotherapy. In this multi-cen...

DOG1 expression is common in human tumors: A tissue microarray study on more than 15,000 tissue samples.

Nov 01, 2021

DOG1 (Discovered on GIST1) is a voltage-gated calcium-activated chloride and bicarbonate channel that is highly expressed in interstitial cells of Cajal and in gastrointestinal stromal tumors (GIST) d...

Copy number variants within AZF region of Y chromosome and their association with idiopathic male infertility in Serbian population.

Nov 01, 2021

Results of numerous studies gave contradictory conclusions when analysing associations between copy number variants (CNVs) within the azoospermia factor (AZF) locus of the Y chromosome and idiopathic ...

Design, synthesis and binding mode of interaction of novel small molecule o-hydroxy benzamides as HDAC3-selective inhibitors with promising antitumor effects in 4T1-Luc breast cancer xenograft model.

Nov 01, 2021

Histone deacetylase 3 (HDAC3) is one of the most promising targets to develop anticancer therapeutics. In continuation of our quest for selective HDAC3 inhibitors, a series of small molecules having o...

CCR5 is a prognostic biomarker and an immune regulator for triple negative breast cancer.

Nov 01, 2021

This study aims to explore the clinical implications and potential mechanistic functions of CCR5 in triple negative breast cancer. Briefly, we demonstrated that CCR5 is overexpressed in TNBC and is as...

Racial/Ethnic Disparity Found in Severe Maternal Morbidity

Oct 25, 2021

Racial and ethnic disparities in maternal health outcomes are pronounced and persistent in the United States, and—to some extent—remain unexplained, according to Alecia J. McGregor, PhD. “In par...

Population Pharmacokinetic Modeling and Probability of Pharmacodynamic Target Attainment for Ceftazidime-Avibactam in Pediatric Patients Aged 3 Months and Older.

Oct 25, 2021

Increasing prevalence of infections caused by antimicrobial-resistant Gram-negative bacteria represents a global health crisis, and while several novel therapies that target various aspects of antimic...

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