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OB/GYN General

Strand displacement amplification triggered 3D DNA roller assisted CRISPR/Cas12a electrochemiluminescence cascaded signal amplification for sensitive detection of Ec-16S rDNA.

Jan 29, 2024

Escherichia coli can cause gastrointestinal infection, urinary tract infection and other infectious diseases. Accurate detection of Escherichia coli 16S rDNA (Ec-16S rDNA) in clinical practice is of g...

New micro-hole zone catheter reduces residual urine and mucosal microtrauma in a lower urinary tract model.

Jan 29, 2024

Urinary tract infections (UTIs) are the main complication associated with clean intermittent catheterization (CIC) and are facilitated by post-void residual urine and trauma to the mucosa during voidi...

Glycemic load, but not glycemic index, is associated with an increased risk of ovarian cancer: A systematic review and meta-analysis.

Jan 29, 2024

The association between glycemic index (GI),glycemic load (GL) and ovarian cancer risk remains unclear. Carbohydrate intake promotes insulin secretion, leading to cell proliferation and invasion. We h...

Reproductive risk factors across the female lifecourse and later metabolic health.

Jan 29, 2024

Metabolic health is characterized by optimal blood glucose, lipids, cholesterol, blood pressure, and adiposity. Alterations in these characteristics may lead to the development of type 2 diabetes mell...

Delayed diagnosis and treatment of adolescents and young women with suspected endometriosis.

Jan 29, 2024

Early diagnosis and treatment of endometriosis in adolescents and young women is considered essential for improving their quality of life and for prevention of long-term complications. In adult women ...

Omission of axillary lymph node dissection for breast cancer patients with three or more positive sentinel lymph nodes.

Jan 29, 2024

The ACOSOG Z0011 (Z11) trial assessed the benefit of axillary dissection (ALND) for breast cancer patients with sentinel lymph node (SLN) metastases; however, Z11 excluded patients with ≥ 3 positi...

Automatic data augmentation to improve generalization of deep learning in H&E stained histopathology.

Jan 29, 2024

In histopathology practice, scanners, tissue processing, staining, and image acquisition protocols vary from center to center, resulting in subtle variations in images. Vanilla convolutional neural ne...

Risk factors for new renal scarring in children with vesicoureteral reflux receiving continuous antibiotic prophylaxis.

Jan 22, 2024

To investigate the risk factors for new renal scarring (NRS) in children with vesicoureteral reflux (VUR) receiving continuous antibiotic prophylaxis (CAP). This was a single-center cohort study. The ...

FTO protein regulates the TGF-β signalling pathway through RNA N6-methyladenosine modification to induce unexplained recurrent spontaneous abortion.

Jan 22, 2024

Recent studies have revealed the involvement of RNA m6A modification in embryonic development; however, the relationship between aberrant RNA m6A modification and unexplained recurrent spontaneous abo...

Results of a randomised Phase II trial of olaparib, chemotherapy or olaparib and cediranib in patients with platinum-resistant ovarian cancer.

Jan 22, 2024

OCTOVA compared the efficacy of olaparib (O) versus weekly paclitaxel (wP) or olaparib + cediranib (O + C) in recurrent ovarian cancer (OC).The main aim of the OCTOVA trial was to determine the pr...

Engineering Improved Car T Cell Products with A Multi-Cytokine Particle Platform for Hematologic and Solid Tumors.

Jan 22, 2024

Despite the remarkable clinical efficacy of chimeric antigen receptor (CAR) T cells in hematological malignancies, only a subset of patients achieve a durable complete response (dCR). DCR has been cor...

Combined cystoscopic-abdominal vs. abdominal only route for complete excision of large deep endometriosis nodules infiltrating the supratrigonal area of the bladder: a comparative study.

Jan 22, 2024

Surgical excision of large deep endometriosis nodules infiltrating the bladder may be challenging, particularly when the nodule limits are close to the trigone and ureteral orifice. Bladder nodules ha...

Transforming growth factor-induced gene TGFBI is correlated with the prognosis and immune infiltrations of breast cancer.

Jan 22, 2024

Transforming growth factor β (TGFβ) is a critical regulator of lung metastasis of breast cancer and is correlated with the prognosis of breast cancer. However, not all TGFβ stimulated genes were fu...

circNINL facilitates aerobic glycolysis, proliferation, invasion, and migration in lung cancer by sponging miR-3918 to mediate FGFR1 expression.

Jan 22, 2024

Previously characterized as an oncogenic player in breast cancer, the function of circular RNA NINL (circNINL) in lung cancer (LC) remained elusive. This study aimed to delineate the biological role o...

Computational Phenotyping of OMOP CDM Normalized EHR for Prenatal and Postpartum Episodes: An Informatics Framework and Clinical Implementation on All of Us.

Jan 22, 2024

The use of Electronic Health Records (EHR) in pregnancy care and obstetrics-gynecology (OB/GYN) research has increased in recent years. In pregnancy, timing is important because clinical characteristi...

Digital remote monitoring for screening and early detection of urinary tract infections.

Jan 15, 2024

Urinary Tract Infections (UTIs) are one of the most prevalent bacterial infections in older adults and a significant contributor to unplanned hospital admissions in People Living with Dementia (PLWD),...

Effectiveness and safety of intravesical Gentamicin therapy in patients with recurrent urinary tract infections caused by multidrug resistant organisms.

Jan 15, 2024

A prospective study was conducted at the Liaquat National Hospital and Medical College, Karachi, to determine the effectiveness, feasibility, and safety of intravesical Gentamicin therapy among patien...

Value of painless transvaginal four-dimensional hysterosalpingo contrast sonography in reducing venous intravasation: a comparative study.

Jan 15, 2024

To investigate the value of painless transvaginal four-dimensional hysterosalpingo contrast sonography (TV 4-D HyCoSy) in reducing venous intravasation and its influencing factors through a retrospect...

Comprehensive analyses of mitophagy-related genes and mitophagy-related lncRNAs for patients with ovarian cancer.

Jan 15, 2024

Both mitophagy and long non-coding RNAs (lncRNAs) play crucial roles in ovarian cancer (OC). We sought to explore the characteristics of mitophagy-related gene (MRG) and mitophagy-related lncRNAs (MRL...

Fertility detection of unincubated chicken eggs by hyperspectral transmission imaging in the Vis-SWNIR region.

Jan 15, 2024

Detection of infertile eggs prior to incubation can lead to an increase in the hatchability rate and prevent the wastage of billions of non-fertile eggs ended up by failed incubation. In this study, t...

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