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OB/GYN General

Repurposing new drug candidates and identifying crucial molecules underlying PCOS Pathogenesis Based On Bioinformatics Analysis.

Sep 06, 2021

Polycystic ovary syndrome affects 7% of women of reproductive ages. Poor-quality oocytes, along with lower cleavage and implantation rates, reduce fertilization.This study aimed to determine crucial m...

MiR-337-3p suppresses migration and invasion of breast cancer cells by downregulating ESRP1.

Sep 06, 2021

Breast cancer (BC) is a common malignant tumor in women, and a considerable number of studies show that aberrant expression of miRNA is correlated with BC development. By analyzing TCGA-BRCA database ...

Prognostic impact of HER2-low expression in hormone receptor positive early breast cancer.

Sep 06, 2021

Recent data suggest that human epidermal growth factor receptor 2 (HER2)-low breast cancer may represent a distinct entity. We aimed to compare disease characteristics and outcomes between HER2-low an...

Photobiomodulation therapy for the prevention of acute radiation dermatitis in breast cancer patients undergoing hypofractioned whole-breast irradiation (LABRA trial).

Sep 06, 2021

To evaluate the efficacy of photobiomodulation therapy in breast cancer patients post-lumpectomy undergoing hypofractionated whole-breast irradiation (HF-WBI) for the prevention and management of acut...

Utilizing Structured Worksheets to Strengthen Resident Teaching on the OB/GYN Clerkship.

Sep 06, 2021

To determine if structured worksheets can aid resident teaching on the obstetrics and gynecology (OB/GYN) clerkship.We developed structured worksheets to aid residents in teaching medical students. In...

The Fundamentals of Vaginal Surgery pilot study: developing, validating, and setting proficiency scores for a vaginal surgical skills simulation system.

Sep 06, 2021

Surgical training in the simulation lab can develop basic skills that translate to the operating room. Standardized, basic skills programs that are supported by validated assessment measures exist for...

ACGME milestones in global health: Need for standardized assessment of global health training in Ob/Gyn residency.

Sep 06, 2021

Collective interest in global health training during U.S. Ob/Gyn residency has grown over the past decade. Benefits of participation in global health electives have been well described. This review se...

Mental Health Neglect Among Physicians

Sep 05, 2021

Previous research has suggested high rates of suicide and depression among physicians when compared with the general public. Debilitating mental illness can critically impact physicians’ ability to ...

Comparative phenotypic characterization of hybrid Shiga toxin-producing / uropathogenic Escherichia coli, canonical uropathogenic and Shiga toxin-producing Escherichia coli.

Aug 26, 2021

Hybrid Shiga toxin (Stx)-producing Escherichia coli (STEC) and uropathogenic E. coli (UPEC) strains are phylogenetically positioned between STEC and UPEC and can cause both diarrhea and urinary tract ...

Integrated Ultrasound with Urodynamics Illustrates Effect of Bladder Volume on Upper Tract Dilation: Should We Trust Surveillance Ultrasounds?

Aug 26, 2021

To evaluate if ultrasound during urodynamics (uUS) will show that traditional ultrasound (tUS) routinely underestimates the potential magnitude of upper tract dilation (UTD).Prospective pilot study of...

Maternal, perinatal and childhood outcomes of the PPROMEXIL-III cohort: Pregnancies complicated by previable prelabor rupture of membranes.

Aug 26, 2021

Perinatal mortality after previable prelabor rupture of membranes (previable PROM) might be underestimated as most studies exclude patients with poor prognosis, or solely include patients in tertiary-...

Liposomal paclitaxel induces apoptosis, cell death, inhibition of migration capacity and antitumoral activity in ovarian cancer.

Aug 26, 2021

The main goal of this study is to evaluate the efficacy of the paclitaxel (PTX) drug formulated with a liposomal nanosystem (L-PTX) in a peritoneal carcinomatosis derived from ovarian cancer. In vitro...

Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers.

Aug 26, 2021

Weight gain and other anthropometric measures on the risk of ovarian cancer for women with BRCA mutations are not known. We conducted a prospective analysis of weight change since age 18, height, body...

Impact of COVID-19 on medical treatment patterns in gynecologic oncology: a MITO group survey.

Aug 26, 2021

COVID-19 is a global public health emergency. The increasing spread of COVID-19 presents challenges for the clinical care of patients with gynecological tumors. The Multicenter Italian Trials in Ovari...

Effects of serum irisin, neuregulin4, and weight management on obese adolescent girls with polycystic ovary syndrome.

Aug 26, 2021

The study is aimed at investigating the association of serum irisin、Neuregulin 4 (NRG4), and Anti-müllerian hormone (AMH) with adolescent obesity with Polycystic ovary syndrome (PCOS) and the effic...

Prevalence of Y chromosome microdeletion in azoospermia factor subregions among infertile men from West Bengal, India.

Aug 26, 2021

Etiology of male infertility is intriguing and Y chromosome microdeletion within azoospermia factor (AZF) sub-regions is considered major cause. We conducted a screening for Y chromosome microdeletion...

The Effect of Dapsone in Testosterone Enanthate-Induced Polycystic Ovary Syndrome in Rat.

Aug 26, 2021

One of the most common reasons for infertility is polycystic ovary syndrome (PCOS). PCOS is related to metabolic syndrome, weight gain, type 2 diabetes mellitus, and cardiovascular diseases. Some of t...

A Robust Breast ultrasound segmentation method under noisy annotations.

Aug 26, 2021

A large-scale training data and accurate annotations are fundamental for current segmentation networks. However, the characteristic artifacts of ultrasound images always make the annotation task compl...

The Cost-Effectiveness of Adjuvant Tamoxifen Treatment of Hormone Receptor-Positive Early Breast Cancer Among Premenopausal and Perimenopausal Ghanaian Women.

Aug 26, 2021

Most breast cancer cases in Ghana occur in premenopausal and perimenopausal (PPM) women. This study evaluated the cost-effectiveness of tamoxifen compared with no tamoxifen for the adjuvant treatment...

Trends in incidence, treatment, survival and subsequent breast cancer in lobular carcinoma in situ in the Netherlands: A population-based analysis.

Aug 26, 2021

We analysed incidence, treatment, survival, occurrence of ductal carcinoma in situ (DCIS) and invasive breast cancer (IBC) after lobular carcinoma in situ (LCIS) in the Netherlands.All women diagnosed...

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