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OB/GYN General

Nurse perspectives on the psychosocial care of patients with urinary incontinence in home hospice: A qualitative study.

Sep 06, 2021

Urinary incontinence is prevalent among patients receiving home hospice and presents multiple care management challenges for nurses and family caregivers.This study sought to understand how urinary in...

The Impact of Preoperative Pelvic Pain on Outcomes after Vaginal Reconstructive Surgery.

Sep 06, 2021

Pelvic pain is a debilitating condition that is common among women with pelvic floor disorders. Limited information is known about the impact of preoperative pelvic pain on outcomes after vaginal reco...

Hypoxia-induced DEC1 mediates trophoblast cell proliferation and migration via HIF1α signaling pathway.

Sep 06, 2021

In early pregnancy, hypoxia is a typical extrinsic factor that regulates EVT functions including proliferation, migration and invasion which are essential for a successful pregnancy. Human differentia...

Adequacy of prenatal care use among pregnant women with epilepsy: A population-based, cross-sectional study, Finland, 2000-2014.

Sep 06, 2021

To examine the association between epilepsy and frequency and time of initiation of prenatal care use among pregnant women in Finland.We conducted a nationally representative, population-based cross-s...

Multiple genetic variants predict the progression-free survival of bevacizumab plus chemotherapy in advanced ovarian cancer: A retrospective study.

Sep 06, 2021

Bevacizumab (BV) plus chemotherapy is broadly used in advanced ovarian cancer (OC). However, the efficacy of BV-based regimens for advanced OC patients is not satisfactory. Therefore, it is urgent to ...

An investigation of cross-sectional associations of a priori-selected dietary components with circulating bile acids.

Sep 06, 2021

A growing body of literature suggests chronically higher bile acid (BA) concentrations may be associated with multiple health conditions. Diet may affect BA metabolism and signaling; however, evidence...

Activating a collaborative innate-adaptive immune response to control metastasis.

Sep 06, 2021

Tumor-associated macrophages (TAMs) promote metastasis and inhibit T cells, but macrophages can be polarized to kill cancer cells. Macrophage polarization could thus be a strategy for controlling can...

Repurposing new drug candidates and identifying crucial molecules underlying PCOS Pathogenesis Based On Bioinformatics Analysis.

Sep 06, 2021

Polycystic ovary syndrome affects 7% of women of reproductive ages. Poor-quality oocytes, along with lower cleavage and implantation rates, reduce fertilization.This study aimed to determine crucial m...

MiR-337-3p suppresses migration and invasion of breast cancer cells by downregulating ESRP1.

Sep 06, 2021

Breast cancer (BC) is a common malignant tumor in women, and a considerable number of studies show that aberrant expression of miRNA is correlated with BC development. By analyzing TCGA-BRCA database ...

Prognostic impact of HER2-low expression in hormone receptor positive early breast cancer.

Sep 06, 2021

Recent data suggest that human epidermal growth factor receptor 2 (HER2)-low breast cancer may represent a distinct entity. We aimed to compare disease characteristics and outcomes between HER2-low an...

Photobiomodulation therapy for the prevention of acute radiation dermatitis in breast cancer patients undergoing hypofractioned whole-breast irradiation (LABRA trial).

Sep 06, 2021

To evaluate the efficacy of photobiomodulation therapy in breast cancer patients post-lumpectomy undergoing hypofractionated whole-breast irradiation (HF-WBI) for the prevention and management of acut...

Utilizing Structured Worksheets to Strengthen Resident Teaching on the OB/GYN Clerkship.

Sep 06, 2021

To determine if structured worksheets can aid resident teaching on the obstetrics and gynecology (OB/GYN) clerkship.We developed structured worksheets to aid residents in teaching medical students. In...

The Fundamentals of Vaginal Surgery pilot study: developing, validating, and setting proficiency scores for a vaginal surgical skills simulation system.

Sep 06, 2021

Surgical training in the simulation lab can develop basic skills that translate to the operating room. Standardized, basic skills programs that are supported by validated assessment measures exist for...

ACGME milestones in global health: Need for standardized assessment of global health training in Ob/Gyn residency.

Sep 06, 2021

Collective interest in global health training during U.S. Ob/Gyn residency has grown over the past decade. Benefits of participation in global health electives have been well described. This review se...

Mental Health Neglect Among Physicians

Sep 05, 2021

Previous research has suggested high rates of suicide and depression among physicians when compared with the general public. Debilitating mental illness can critically impact physicians’ ability to ...

Comparative phenotypic characterization of hybrid Shiga toxin-producing / uropathogenic Escherichia coli, canonical uropathogenic and Shiga toxin-producing Escherichia coli.

Aug 26, 2021

Hybrid Shiga toxin (Stx)-producing Escherichia coli (STEC) and uropathogenic E. coli (UPEC) strains are phylogenetically positioned between STEC and UPEC and can cause both diarrhea and urinary tract ...

Integrated Ultrasound with Urodynamics Illustrates Effect of Bladder Volume on Upper Tract Dilation: Should We Trust Surveillance Ultrasounds?

Aug 26, 2021

To evaluate if ultrasound during urodynamics (uUS) will show that traditional ultrasound (tUS) routinely underestimates the potential magnitude of upper tract dilation (UTD).Prospective pilot study of...

Maternal, perinatal and childhood outcomes of the PPROMEXIL-III cohort: Pregnancies complicated by previable prelabor rupture of membranes.

Aug 26, 2021

Perinatal mortality after previable prelabor rupture of membranes (previable PROM) might be underestimated as most studies exclude patients with poor prognosis, or solely include patients in tertiary-...

Liposomal paclitaxel induces apoptosis, cell death, inhibition of migration capacity and antitumoral activity in ovarian cancer.

Aug 26, 2021

The main goal of this study is to evaluate the efficacy of the paclitaxel (PTX) drug formulated with a liposomal nanosystem (L-PTX) in a peritoneal carcinomatosis derived from ovarian cancer. In vitro...

Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers.

Aug 26, 2021

Weight gain and other anthropometric measures on the risk of ovarian cancer for women with BRCA mutations are not known. We conducted a prospective analysis of weight change since age 18, height, body...

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