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OB/GYN General

MRI based morphological examination of the placenta.

Sep 20, 2021

Ultrasound is widely used as the initial diagnostic imaging modality during pregnancy with both high spatial and temporal resolution. Although MRI in pregnancy has long focused on the fetus, its use i...

4-Flourophenyl-substituted 5H-indeno[1,2-b]pyridinols with enhanced topoisomerase IIα inhibitory activity: Synthesis, biological evaluation, and structure-activity relationships.

Sep 20, 2021

A series of fluorinated and hydroxylated 2,4-diphenyl indenopyridinols were designed and synthesized using l-proline-catalyzed and microwave-assisted synthetic methods for the development of new antic...

OB/GYN residents' training, attitudes, and comfort level regarding genetics.

Sep 20, 2021

While the availability, utility, and complexity of genetic testing expands, limited information exists regarding obstetrician-gynecologist (OB/GYN) residents' knowledge of genetics and confidence in p...

"We're called upon to be nonjudgmental": A qualitative exploration of United States medical students' discussions of abortion as a reflection of their professionalism.

Sep 20, 2021

Medical educators may assess learners' professionalism through clinical scenarios eliciting value conflicts - situations in which an individual's values differ from others' perceived values. We examin...

Uterine Cancer: Comparing Treatment Approaches in Women With Distant Organ Metastases

Sep 15, 2021

“According to current estimates, approximately 9% of patients with uterine cancer have metastatic disease at the time of their initial presentation,” says Yuefeng Wang, MD, PhD. “In addition to ...

Nurse perspectives on the psychosocial care of patients with urinary incontinence in home hospice: A qualitative study.

Sep 06, 2021

Urinary incontinence is prevalent among patients receiving home hospice and presents multiple care management challenges for nurses and family caregivers.This study sought to understand how urinary in...

The Impact of Preoperative Pelvic Pain on Outcomes after Vaginal Reconstructive Surgery.

Sep 06, 2021

Pelvic pain is a debilitating condition that is common among women with pelvic floor disorders. Limited information is known about the impact of preoperative pelvic pain on outcomes after vaginal reco...

Hypoxia-induced DEC1 mediates trophoblast cell proliferation and migration via HIF1α signaling pathway.

Sep 06, 2021

In early pregnancy, hypoxia is a typical extrinsic factor that regulates EVT functions including proliferation, migration and invasion which are essential for a successful pregnancy. Human differentia...

Adequacy of prenatal care use among pregnant women with epilepsy: A population-based, cross-sectional study, Finland, 2000-2014.

Sep 06, 2021

To examine the association between epilepsy and frequency and time of initiation of prenatal care use among pregnant women in Finland.We conducted a nationally representative, population-based cross-s...

Multiple genetic variants predict the progression-free survival of bevacizumab plus chemotherapy in advanced ovarian cancer: A retrospective study.

Sep 06, 2021

Bevacizumab (BV) plus chemotherapy is broadly used in advanced ovarian cancer (OC). However, the efficacy of BV-based regimens for advanced OC patients is not satisfactory. Therefore, it is urgent to ...

An investigation of cross-sectional associations of a priori-selected dietary components with circulating bile acids.

Sep 06, 2021

A growing body of literature suggests chronically higher bile acid (BA) concentrations may be associated with multiple health conditions. Diet may affect BA metabolism and signaling; however, evidence...

Activating a collaborative innate-adaptive immune response to control metastasis.

Sep 06, 2021

Tumor-associated macrophages (TAMs) promote metastasis and inhibit T cells, but macrophages can be polarized to kill cancer cells. Macrophage polarization could thus be a strategy for controlling can...

Repurposing new drug candidates and identifying crucial molecules underlying PCOS Pathogenesis Based On Bioinformatics Analysis.

Sep 06, 2021

Polycystic ovary syndrome affects 7% of women of reproductive ages. Poor-quality oocytes, along with lower cleavage and implantation rates, reduce fertilization.This study aimed to determine crucial m...

MiR-337-3p suppresses migration and invasion of breast cancer cells by downregulating ESRP1.

Sep 06, 2021

Breast cancer (BC) is a common malignant tumor in women, and a considerable number of studies show that aberrant expression of miRNA is correlated with BC development. By analyzing TCGA-BRCA database ...

Prognostic impact of HER2-low expression in hormone receptor positive early breast cancer.

Sep 06, 2021

Recent data suggest that human epidermal growth factor receptor 2 (HER2)-low breast cancer may represent a distinct entity. We aimed to compare disease characteristics and outcomes between HER2-low an...

Photobiomodulation therapy for the prevention of acute radiation dermatitis in breast cancer patients undergoing hypofractioned whole-breast irradiation (LABRA trial).

Sep 06, 2021

To evaluate the efficacy of photobiomodulation therapy in breast cancer patients post-lumpectomy undergoing hypofractionated whole-breast irradiation (HF-WBI) for the prevention and management of acut...

Utilizing Structured Worksheets to Strengthen Resident Teaching on the OB/GYN Clerkship.

Sep 06, 2021

To determine if structured worksheets can aid resident teaching on the obstetrics and gynecology (OB/GYN) clerkship.We developed structured worksheets to aid residents in teaching medical students. In...

The Fundamentals of Vaginal Surgery pilot study: developing, validating, and setting proficiency scores for a vaginal surgical skills simulation system.

Sep 06, 2021

Surgical training in the simulation lab can develop basic skills that translate to the operating room. Standardized, basic skills programs that are supported by validated assessment measures exist for...

ACGME milestones in global health: Need for standardized assessment of global health training in Ob/Gyn residency.

Sep 06, 2021

Collective interest in global health training during U.S. Ob/Gyn residency has grown over the past decade. Benefits of participation in global health electives have been well described. This review se...

Mental Health Neglect Among Physicians

Sep 05, 2021

Previous research has suggested high rates of suicide and depression among physicians when compared with the general public. Debilitating mental illness can critically impact physicians’ ability to ...

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