Advertisement

OB/GYN General

A multi-pollutant assessment of preconception persistent endocrine disrupting chemicals and incident pregnancy loss.

Aug 02, 2021

A few endocrine disrupting chemicals (EDCs) have been associated with pregnancy loss often as reported by women, though there has been no study of EDC mixtures and pregnancy loss in keeping with the n...

Advancing health through research: A scoping review of and model for adjunctive psychosocial interventions to improve outcomes for perinatal women with bipolar disorder.

Aug 02, 2021

We aimed to identify randomized clinical trials (RCTs) which evaluated the efficacy of adjunctive psychosocial interventions to improve outcomes during the perinatal period for women with bipolar diso...

Perforated Meckel's diverticulum in omphalocele in a newborn: A case report of an uncommon presentation from northern Tanzania.

Aug 02, 2021

The concurrent existence of Omphalocele and Meckel's diverticulum is not unheard of but is relatively uncommon. A few cases of their coexistence have been reported. Due to the uncommon dual presentati...

Ovarian cancer surveillance in the clinical follow up of women with known BRCA1 or BRCA2 pathogenic variants in a large health care system.

Aug 02, 2021

To assess CA 125 and transvaginal ultrasound surveillance in women with BRCA1 or BRCA2 pathogenic variants in a pragmatic clinical setting with>1 year follow up.Retrospective cohort study in a larg...

Ambient air pollution and ovarian cancer survival in California.

Aug 02, 2021

To examine whether exposure to ambient ozone, particulate matter with diameter less than 2.5 μm (PM), nitrogen dioxide (NO), and distance to major roadways (DTR) impact ovarian cancer-specific surviv...

PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage.

Aug 02, 2021

Polyguanine tracts (PolyGs) are short guanine homopolymer repeats that are prone to accumulating mutations when cells divide. This feature makes them especially suitable for cell lineage tracing, whic...

Influence of inguinal hernia repair on sperm autoimmunity: The largest single center experience.

Aug 02, 2021

Studies on immunological infertility after inguinal hernia correction are few and not very representative. Anti-sperm antibodies (ASA) have been shown to reduce male fertility. Although the extent of ...

UPLC-MS/MS assay for the simultaneous determination of pyrotinib and its oxidative metabolite in rat plasma: application to a pharmacokinetic study.

Aug 02, 2021

Pyrotinib is an irreversible EGFR/HER2 inhibitor, which has been approved for the treatment of breast cancer. The aim of this work was to establish a quantification method for simultaneous determinati...

Reduced infiltration of T-regulatory cells in tumours from mice fed daily with gamma-tocotrienol supplementation.

Aug 02, 2021

Gamma-tocotrienol (γT3) is an analogue of vitamin E with beneficial effects on the immune system, including immune-modulatory properties. This study reports the immune-modulatory effects of daily sup...

Metabolic reprograming confers tamoxifen resistance in breast cancer.

Aug 02, 2021

Breast cancer is the most common cancer among females and the leading cause of cancer-related deaths. Approximately 70 % of breast cancers are estrogen receptor (ER) positive. An ER antagonist such ...

Recommendations for Dosing & Administering Medical Cannabis for Chronic Pain

Jul 31, 2021

Despite a need for more robust evidence, many patients with chronic pain are being treated with medical cannabis and cannabinoids. In the Journal of Cannabis Research, the Global Task Force on Dosing ...

Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial.

Jul 29, 2021

Determination of optimal treatment durations for common infectious diseases is an important strategy to preserve antibiotic effectiveness.To determine whether 7 days of treatment is noninferior to 14 ...

Impact of the availability of midurethral slings on treatment strategies for stress urinary incontinence: a cost-effectiveness analysis.

Jul 29, 2021

To perform a cost-effectiveness analysis for the surgical and non-surgical management of stress urinary incontinence (SUI) with and without the availability of midurethral sling.Cost-effectiveness ana...

Longitudinal exposure to consumer product chemicals and changes in plasma oxylipins in pregnant women.

Jul 29, 2021

Exposure to consumer product chemicals during pregnancy may increase susceptibility to pregnancy disorders by influencing maternal inflammation. However, effects on specific inflammatory pathways have...

A large-scale multi-institutional study evaluating prognostic aspects of positive ascites cytology and effects of therapeutic interventions in epithelial ovarian cancer.

Jul 29, 2021

Positive ascites cytology is a strong prognostic factor in patients with early-stage ovarian cancer (OvCa). However, limited information is currently available on the impact of positive ascites cytolo...

Incidence of malignant transformation in the oviductal fimbria in laying hens, a preclinical model of spontaneous ovarian cancer.

Jul 29, 2021

Ovarian high grade serous carcinoma (HGSC) is a lethal form of ovarian cancer (OVCA). In most cases it is detected at late stages as the symptoms are non-specific during early stages. Emerging informa...

Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers.

Jul 29, 2021

Defects in translation lead to changes in the expression of proteins that can serve as drivers of cancer formation. Here, we show that cytosolic NAD synthesis plays an essential role in ovarian cancer...

Morphological features of the secretory phase endometrium in women with unexplained infertility.

Jul 29, 2021

In this study, we evaluated the structural features of the endometrial tissues, the immunohistochemical expression of MUC-1, which plays an important role in implantation, and the biochemical markers ...

Expression of Hypoxia-Inducible Factor1-α in Varicocele Disease: a Comprehensive Systematic Review.

Jul 29, 2021

Hypoxia has been suggested as an important pathophysiological feature in varicocele disease. On the other hand, the expression of hypoxia-inducible factor 1-alpha (HIF1-α) is associated with the inci...

Evolution of physical activity and body weight changes in breast cancer survivors five years after diagnosis - VICAN 2 & 5 French national surveys.

Jul 29, 2021

Regular physical activity (PA) and healthy body weight have proven benefits on survival in breast cancer (BC) survivors. We aimed to define predictors of long-term PA and weight gain in a representati...

SUBSPECIALTIES

Advertisement