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OB/GYN General

Safety of hormone replacement therapy in women with a history of cervical adenocarcinoma.

Jul 15, 2021

Studies investigating the safety of hormone replacement therapy in cervical cancer have predominantly included patients with squamous disease. Pathological studies have identified estrogen receptor po...

Comparison of the efficacy of letrozole stair-step protocol with clomiphene citrate stair-step protocol in the management of clomiphene citrate-resistant polycystic ovary syndrome patients.

Jul 15, 2021

We sought to compare the efficacy of the letrozole (LTZ) stair-step protocol with clomiphene citrate (CC) stair-step protocol in the management of 150 mg dose of CC-resistant polycystic ovary syndro...

Bi-allelic truncating variants in CFAP206 cause male infertility in human and mouse.

Jul 15, 2021

Spermatozoa are polarized cells with a head and a flagellum joined together by the connecting piece. Flagellum integrity is critical for normal sperm function, and flagellum defects consistently lead ...

Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women.

Jul 15, 2021

Approximately 40% of human pregnancies are unintended, indicating a need for more acceptable effective contraception methods. New antibody production systems make it possible to manufacture reagent-gr...

Cancer Mortality and Research Outcomes in a Rural State.

Jul 15, 2021

North Dakota is a rural state with high rates of cancer. Determining how various demographic, geographic, and funding factors contributed to cancer incidence on a state and county level helps improve ...

Building and Behavior of A pH-Stimuli Responsive Chitosan Nanoparticles Loaded with Folic Acid Conjugated Gemcitabine Silver Colloids In MDA-MB-453 Metastatic Breast Cancer Cell Line and Pharmacokinetics In Rats.

Jul 15, 2021

The pH-stimuli release behavior of nanoformulations may enhance the success rate of chemotherapeutic drugs in cancers by site-specific delivery of drugs to cancer tissues. The aim of the present study...

Risk and influencing factors for subsequent primary lung cancer after treatment of breast cancer: a systematic review and two meta-analyses based on four million cases.

Jul 15, 2021

To compare the risk of developing lung cancer between breast cancer patients and the general population and explore the risk factors for the development of primary lung cancer after treatment for brea...

A survey of career-decision factors for obstetrics and gynecology residents in Taiwan.

Jul 15, 2021

The recruitment of obstetrics and gynecology residents has been challenging in Taiwan since 2000. There are a lots factors influencing applying, including career interest and prospects, lifestyle, sal...

Well-being in trainee and faculty physicians.

Jul 15, 2021

Physician well-being remains a critical topic with limited information concerning the impact of the progression of training and duty hours. To date, our knowledge and interventions have not adequatel...

Antifungal activity of nitroxoline against Candida auris isolates.

Jul 12, 2021

To investigate the in vitro activity of nitroxoline against a molecularly characterized collection of clinical Candida auris isolates.Thirty-five clinical isolates of C. auris from diverse sources rep...

Five versus seven days of nitrofurantoin for urinary tract infections in women with diabetes: a retrospective cohort study.

Jul 12, 2021

To compare the effectiveness of five versus seven days of nitrofurantoin treatment for urinary tract infection (UTI) in diabetic women.Data were collected retrospectively from Dutch general practition...

Genetic parameters and genetic trends for reproductive traits in Egyptian buffalo.

Jul 12, 2021

Reproductive traits are important for farm profitability because failure to reproduce is the primary reason for culling animals. Study objectives were to estimate genetic parameters and evaluate the t...

Environmental metal exposure and growth to 10 years of age in a longitudinal mother-child cohort in rural Bangladesh.

Jul 12, 2021

Early-life exposure to arsenic (As), cadmium (Cd), and lead (Pb) has been linked to smaller birth and early childhood anthropometry, but little is known beyond the first years in life.To evaluate the ...

Association of dietary tomato intake with bladder cancer risk in a prospective cohort of 101,683 individuals with 12.5 years of follow-up.

Jul 12, 2021

Previous studies have provided limited evidence for the effect of tomato intake on bladder cancer incidence. This study aimed to evaluate the association between dietary tomato or lycopene consumption...

Extracellular matrix protein-1 secretory isoform promotes ovarian cancer through increasing alternative mRNA splicing and stemness.

Jul 12, 2021

Extracellular matrix protein-1 (ECM1) promotes tumorigenesis in multiple organs but the mechanisms associated to ECM1 isoform subtypes have yet to be clarified. We report in this study that the secret...

Anti-Ro52 antibody is highly prevalent and a marker of better prognosis in patients with ovarian cancer.

Jul 12, 2021

Anti-Ro52 antibody (Ab) reactivity is highly prevalent in autoimmune rheumatic diseases (ARDs), mainly Sjögren's syndrome (SjS) and systemic lupus erythematosus (SLE), but also in other inflammatory ...

Structured report for dynamic ultrasonography in patients with suspected or known endometriosis: Recommendations of the International Society for Gynecologic Endoscopy (ISGE).

Jul 12, 2021

The International Society for Gynecologic Endoscopy (ISGE) developed this project to establish the recommendations for structured reporting of dynamic ultrasound findings, promoting on this manner the...

A critical appraisal of the circulating levels of differentially expressed microRNA in endometriosis†.

Jul 12, 2021

Endometriosis is a common gynaecological condition characterized by estrogen dependence, chronic pelvic pain, infertility and diagnostic delay of between 5.4 and 12 years. Despite extensive study, no...

Oxoplatin-B, a cisplatin-based platinum(IV) complex with photoactive BODIPY for mitochondria specific "chemo-PDT" activity.

Jul 12, 2021

Oxoplatin-B, a platinum(IV) complex [Pt(NH)Cl(L)(OH)] (1) of 4-methylbenzoic acid (HL) functionalized with 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) was prepared, characterized and its antit...

Application of noise-reduction techniques to machine learning algorithms for breast cancer tumor identification.

Jul 12, 2021

The application of machine learning (ML) techniques to digitized images of biopsied cells for breast cancer diagnosis is an active area of research. We hypothesized that reducing noise in the data wou...

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