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OB/GYN General

Uptake of cancer risk management strategies among women who undergo cascade genetic testing for breast cancer susceptibility genes.

Jun 24, 2021

Uptake of cancer risk management based on inherited predispositions, which encompasses bilateral mastectomy (BLM), bilateral salpingo-oophorectomy (BSO), and intensified screening, is the primary moti...

Hematologic safety of palbociclib in combination with endocrine therapy in patients with benign ethnic neutropenia and advanced breast cancer.

Jun 24, 2021

Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors, including palbociclib, are approved to treat hormone receptor (HR)-positive/human epidermal growth factor receptor 2 (HER2)-negative advanced breast ca...

Physician Gender Preference Amongst Females Attending Obstetrics/Gynecology Clinics.

Jun 24, 2021

The objective of our study was to explore the views and perceptions of female patients attending the obstetrics and gynecology (OB/GYN) outpatient department towards the gender of their healthcare pro...

Exploring Healthcare Super-Utilization in Gynecologic Oncology

Jun 18, 2021

Unplanned acute care continues to be a major contributor to growing healthcare costs in the United States, especially among patients with cancer. Quality measures have been developed to reduce healthc...

Postpartum ultrasound for the diagnosis of obstetric anal sphincter injury.

Jun 17, 2021

This review presents the available data on the diagnosis of obstetric anal sphincter injury (OASI) by postnatal ultrasound imaging. There is increasing evidence that anal sphincter tears are often mis...

Mechanism and Priority of Botulinum Neurotoxin A versus Sacral Neuromodulation for Refractory Overactive Bladder: A Review.

Jun 17, 2021

The treatment of common overactive bladder (OAB) has reached a consensus, but there is not a clear answer to the treatment of refractory OAB (ROAB). ROAB is defined as nonresponsive to treatment with ...

Is Lupus Anticoagulant a Significant Feature of COVID-19? A Critical Appraisal of the Literature.

Jun 17, 2021

The term "lupus anticoagulant (LA)" identifies a form of antiphospholipid antibodies (aPLs) causing prolongation of clotting tests in a phospholipid concentration-dependent manner. LA is one of the la...

Anti-Xa Monitoring of Low-Molecular-Weight Heparin during Pregnancy: A Systematic Review.

Jun 17, 2021

Low-molecular-weight heparin (LMWH) is commonly used for preventing or treating venous thromboembolic disease (VTE) during pregnancy. The physiological changes in maternal metabolism have led to discu...

Potential Strategies to Increase Gynecologic Oncologist Treatment for Ovarian Cancer.

Jun 17, 2021

Evidence shows that treatment by gynecologic oncologists (GOs) increases overall survival among women with ovarian cancer. However, specific strategies for institutions and community-based public heal...

Real-world experience with trabectedin for the treatment of recurrent ovarian cancer.

Jun 17, 2021

: The efficacy and safety of trabectedin/pegylated liposomal doxorubicin (trabectedin/PLD) in patients with recurrent ovarian cancer have been demonstrated in randomized clinical studies. Real-world e...

[Clinical applications of bevacizumab in the treatment of colorectal and ovarian cancer.]

Jun 17, 2021

The development of biological drugs, which began in the 1980s, has revolutionized the treatment of numerous oncological diseases and severely disabling autoimmune diseases, with widely demonstrated ev...

LRH-1 high expression in the ovarian granulosa cells of PCOS patients.

Jun 17, 2021

Polycystic ovary syndrome (PCOS) is considered one of the most common endocrine disorders with heterogeneity. There are also reports that liver receptor homolog 1 [LRH-1 or nuclear receptor subfamily ...

Elevated Anti-Müllerian Hormone Levels in Newborns of Women with Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis Based on Observational Studies.

Jun 17, 2021

We performed this updated systematic review and meta-analysis to evaluate anti-Müllerian hormone levels (AMH) in newborns of mothers with polycystic ovary syndrome (PCOS) compared with healthy contro...

Dissection of phospholipases A reveals multifaceted peptides targeting cancer cells, Leishmania and bacteria.

Jun 17, 2021

Cationic peptides bio-inspired by natural toxins have been recognized as an efficient strategy for the treatment of different health problems. Due to the specific interaction with substrates from biol...

Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models.

Jun 17, 2021

Breast cancer remains one of the leading cancers among women. Cancer stem cells (CSCs) are tumor-initiating cells which drive progression, metastasis, and reoccurrence of the disease. CSCs are resista...

Mat pilates method improve postural alignment women undergoing hormone therapy adjunct to breast cancer treatment. Clinical trial.

Jun 17, 2021

The purpose of the study is to analyze the effects of a mat Pilates intervention on the postural alignment and balance of breast cancer women receiving hormone therapy. A two-arm randomized clinical t...

Examining Long-Term Sexual Outcomes With Exstrophy-Epispadias

Jun 16, 2021

“For children with exstrophy-epispadias complex (EEC), a spectrum of genitourinary malformation, the clinical focus has typically been on reconstruction of the external genitalia and lower urinary t...

Safety and efficiency of modified sacrospinous ligament fixation for apical prolapse: Long-term studies and outcomes.

Jun 14, 2021

To explore the safety and efficiency of modified sacrospinous ligament fixation (MSSF) for apical prolapse.It's a retrospective cohort study. Patients diagnosed with apical prolapse from 2014 to 2019 ...

Safety of Dapagliflozin in Patients with Type 2 Diabetes Mellitus in Saudi Arabia: A Post Authorization Safety Study.

Jun 14, 2021

Sodium-glucose co-transporter-2 (SGLT2) inhibitors moderately reduce glucose levels in type-2 diabetes mellitus (T2DM). Some cases of diabetic ketoacidosis (DKA) were reported with SGLT2 inhibitors. H...

Impact of inappropriate empirical antibiotic treatment on clinical outcomes of urinary tract infections caused by Escherichia coli: a retrospective cohort study.

Jun 14, 2021

We aimed to determine the clinical impact of inappropriate empirical antibiotic treatment (IEAT) compared with appropriate empirical antibiotic treatment (AEAT) in hospitalised patients with urinary t...

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