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OB/GYN General

CD70 antibody-drug conjugate: A potential novel therapeutic agent for ovarian cancer.

Jun 14, 2021

This study aimed to investigate the cytotoxicity of a CD70 antibody-drug conjugate (CD70-ADC) against ovarian cancer in-vitro and in-vivo xenograft models. CD70 expression was assessed in clinical sam...

Knockdown of circ_0075503 suppresses cell migration and invasion by regulating miR-15a-5p and KLF12 in endometriosis.

Jun 14, 2021

Endometriosis is an estrogen-dependent disease. Several researches have reported the dysregulated circular RNAs (circRNAs) in endometriosis, whereas the functions of circRNAs are largely unknown. This...

Population-based mammography screening attendance in Sweden 2017-2018: A cross-sectional register study to assess the impact of sociodemographic factors.

Jun 14, 2021

Sweden has a population-based mammography screening programme for women aged 40-74. The objective of this study was to examine the association between mammography screening attendance and sociodemogra...

Denial of Pregnancy in a Patient With a History of Pseudocyesis.

Jun 14, 2021

Denial of pregnancy is a condition in which a pregnant patient does not believe she is pregnant. This case describes a 23-year-old Caucasian female, with a past psychiatric history of pseudocyesis, st...

Performance of a targeted cell-free DNA prenatal test for 22q11.2 deletions in a large clinical cohort.

Jun 07, 2021

22q11.2 microdeletions are more common than trisomies 18 and 13 combined, but no routine approach to prenatal screening has been established. This study evaluates the clinical sensitivity and specific...

Quality control of ultrasonography markers for Down's syndrome screening: a retrospective study by the laboratory.

Jun 07, 2021

Quality control of ultrasonography markers is necessary to ensure greater efficacy of prenatal aneuploidy screening. The aim of this study was to assess the quality of the crown-rump length (CRL) and ...

The social meanings of choice in living-with advanced breast cancer.

Jun 07, 2021

Individual choice is valorised as a core social value; yet the necessity and desirability of making choices takes on new significance for people living with incurable cancer who are required to make o...

Distress Trajectories in Black and White Breast Cancer Survivors: From Diagnosis to Survivorship.

Jun 07, 2021

Black breast cancer survivors have greater morbidity and mortality than White survivors. However, evidence comparing Black survivors' psychological symptoms with their White counterparts has been mixe...

Prognostic value of the 6-gene OncoMasTR test in hormone receptor-positive HER2-negative early-stage breast cancer: Comparative analysis with standard clinicopathological factors.

Jun 07, 2021

The aim of the study was to assess the prognostic performance of a 6-gene molecular score (OncoMasTR Molecular Score [OMm]) and a composite risk score (OncoMasTR Risk Score [OM]) and to conduct a with...

Genital Tract GAS Infection ISIDOG Guidelines.

Jun 07, 2021

There has been an increasing worldwide incidence of invasive group A streptococcal (GAS) disease in pregnancy and in the puerperal period over the past 30 years. Postpartum Group A streptococci infect...

Advanced Ovarian Cancer: Identifying Opportunities for Prehabilitation

Jun 04, 2021

Patients with epithelial ovarian cancer most commonly present when their disease has reached an advanced stage. “While primary cytoreductive surgery is a treatment option for some patients, others...

Female sexuality before and after sacrocolpopexy or vaginal mesh: is vaginal length one of the key factors?

Jun 03, 2021

We aimed to demonstrate that laparoscopic sacrocolpopexy/cervicopexy (LSC-Cx) versus anterior vaginal mesh (AVM) results in a longer vaginal length without impacting sexual activity or function.We per...

Comprehensive reporting of pelvic floor muscle training for urinary incontinence: CERT-PFMT.

Jun 03, 2021

To produce a pelvic floor muscle training variation of the Consensus on Exercise Reporting Template (CERT-PFMT). Qualitative methods were used to explore the perspectives of physiotherapists who have...

The level of depression, anxiety, and sleep quality in pregnancy during coronavirus disease 2019 pandemic.

Jun 03, 2021

We aimed to evaluate the mental health and sleep quality of pregnant women in different trimesters during coronavirus disease 2019 (COVID-19) pandemic and investigate the effect of quarantine and new ...

Live birth rate with double ovarian stimulation is superior to follicular phase ovarian stimulation per started cycle in poor ovarian responders.

Jun 03, 2021

To compare the outcome of double ovarian stimulation (DOS) with follicular phase ovarian stimulation (FPS) per started cycle in poor ovarian responders (PORs).A total of 204 PORs who underwent ovulati...

Anxiety and depression during pregnancy in the era of COVID-19.

Jun 03, 2021

This study aimed to evaluate anxiety and depression in pregnant women during this global disease.This was a cross-sectional study recruiting 120 pregnant women. The study was conducted at the outpatie...

Molecular characteristics and tumorigenicity of ascites-derived tumor cells: mitochondrial oxidative phosphorylation as a novel therapy target in ovarian cancer.

Jun 03, 2021

Ovarian cancer (OvCa) disseminates primarily intraperitoneally. Detached tumor cell aggregates (spheroids) from the primary tumor are regarded as "metastatic units" that exhibit a low sensitivity to c...

Amphiregulin increases migration and proliferation of epithelial ovarian cancer cells by inducing its own expression via PI3-kinase signaling.

Jun 03, 2021

The epidermal growth factor receptor (EGFR) is overexpressed in many types of cancer, including epithelial ovarian cancer (EOC), and its expression has been found to correlate with advanced stage and ...

The correlation of estrogen receptor 1 and progesterone receptor genes polymorphisms with recurrent pregnancy loss in a cohort of Egyptian women.

Jun 03, 2021

Recurrent pregnancy loss (RPL) represents one of the pregnancy complications affecting 1-3% of women. Sex hormones, progesterone and estrogen play a critical role in the maintenance of pregnancy; they...

Sperm DNA fragmentation and male age: results of in vitro fertilization treatments.

Jun 03, 2021

This study aimed to assess the effects of sperm DNA fragmentation in parents belonging to different age groups. The couples included in the study comprised normozoospermic men and infertile women unde...

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