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OB/GYN General

The Impact of Platinum-Containing Chemotherapies in Advanced Triple-Negative Breast Cancer: Meta-Analytical Approach to Evaluating Its Efficacy and Safety.

May 13, 2021

Triple-negative breast cancer (TNBC), the most common type of breast cancer, is associated with poor patient prognosis. Platinum-containing chemotherapies are commonly used in the treatment and preven...

Physical Activity, Diet, and Incident Urinary Incontinence in Postmenopausal Women: Women's Health Initiative Observational Study.

May 10, 2021

Physical activity and macronutrient intake, important contributors to energy balance, may be independently associated with female urinary incontinence (UI).We evaluated the association of baseline sel...

Heterogeneity in outcome selection, definition and measurement in studies assessing the treatment of cryptoglandular anal fistula: findings from a systematic review.

May 10, 2021

Treatment for cryptoglandular anal fistula (AF) is challenging and a lack of uniform outcomes in the literature prevents direct comparison of treatments. This can be addressed by developing a core out...

Molecular characterization of ESBL- producing uropathogenic Escherichia coli recovered from urine samples of patients attending a University Teaching hospital in Nigeria.

May 10, 2021

Infection of the urinary tract ranks as one of the most common infections affecting people worldwide and its treatment is made complicated by the rising incidence of antibiotic resistance. This study ...

Longitudinal changes in HRV across pregnancy and postpartum: Effect of negative partner relationship qualities.

May 10, 2021

During pregnancy, there are significant physiological changes to support a healthy fetus. Parasympathetic activity normatively decreases across pregnancy, and psychological stress can promote even fur...

Side of ovulation at each end of two- and three-wave interovulatory intervals and before and after pregnancy in cattle.

May 10, 2021

The side of ovulation (left ovary, LO; right ovary, RO) and side of the next ovulation were compared between (1) beginning and end of an interovulatory interval (IOI) and beginning and end of consecut...

Maternal obesity and baseline vitamin D insufficiency alter the response to vitamin D supplementation: a double-blind, randomized trial in pregnant women.

May 10, 2021

The achievement of target 25-hydroxyvitamin D [25(OH)D] concentrations in pregnancy may be altered by maternal obesity.The authors examined the effects of maternal supplementation of 10 μg compared w...

WNT4 balances development versus disease in gynecologic tissues and women's health.

May 10, 2021

The WNT family of proteins are crucial in numerous developmental pathways and tissue homeostasis. WNT4, in particular, is uniquely implicated in development of the female phenotype in the fetus, and i...

[ENTPD5 gene is highly expressed in epithelial ovarian cancer: analysis based on Oncomine database and bioinformatics].

May 10, 2021

To investigate the expression of ENTPD5 in epithelial ovarian cancer and explore its clinical implications.The expression level of ENTPD5 in epithelial ovarian cancer was analyzed based on data from O...

Pre- and post-diagnosis leisure time physical activity and survival following diagnosis with ovarian cancer.

May 10, 2021

Little is known about the influence of pre- and post-diagnosis physical activity on ovarian cancer survival. We investigated this association in two large cohorts, the Nurses' Health Study (NHS) and N...

Validation of a quantitative systems pharmacology model of calcium homeostasis using elagolix Phase 3 clinical trial data in women with endometriosis.

May 10, 2021

Elagolix is a novel, oral gonadotropin-releasing hormone receptor antagonist indicated for the management of moderate to severe pain associated with endometriosis and heavy menstrual bleeding associat...

Alpelisib in combination with everolimus ± exemestane in solid tumours: Phase Ib randomised, open-label, multicentre study.

May 10, 2021

Combined mTORC1 inhibition with everolimus (EVE) and phosphatidylinositol 3-kinase catalytic subunit p110α blockade with alpelisib (ALP) has demonstrated synergistic efficacy in preclinical models an...

A transfer learning with structured filter pruning approach for improved breast cancer classification on point-of-care devices.

May 10, 2021

A significant progress has been made in automated medical diagnosis with the advent of deep learning methods in recent years. However, deploying a deep learning model for mobile and small-scale, low-c...

Dairy foods, calcium, and risk of breast cancer overall and for subtypes defined by estrogen receptor status: a pooled analysis of 21 cohort studies.

May 10, 2021

Epidemiologic studies examining the relations between dairy product and calcium intakes and breast cancer have been inconclusive, especially for tumor subtypes.To evaluate the associations between int...

Knowledge, Attitudes, Behaviors of Women Related to Pregnancy, and Early Childhood Caries Prevention: A Cross-Sectional Pilot Study.

May 10, 2021

Health education interventions during pregnancy can influence maternal oral health (OH), maternal OH-behaviors and children's OH. Interventions that can be delivered at anytime and anywhere, for examp...

Addressing Obstetric Health Disparities among Refugee Populations: Training the Next Generation of Culturally Humble OB/GYN Medical Providers.

May 10, 2021

The burden of increasing obstetric morbidity and mortality in the United States disproportionately affects marginalized and vulnerable populations, including refugees. Many factors have been attribut...

HPV Vaccination Rates Suboptimal Within Ages 9 to 12 Years

May 06, 2021

TUESDAY, May 4, 2021 (HealthDay News) -- Despite increases since 2008, human papillomavirus (HPV) vaccination rates are suboptimal within ages 9 to 12 years, according to a study published online May ...

UVENTA urethral stents: Are we taking a step forward? The first clinical series.

May 06, 2021

To describe first clinical results in term of safety, complications and short term efficacy of temporary placement of UVENTA urethral stent in the treatment of urethral and bladder neck strictures.UVE...

Single-dose amikacin plus 7 days of amoxicillin/clavulanate to treat acute cystitis caused by extended-spectrum beta-lactamase-producing : A retrospective cohort study.

May 06, 2021

Treatment options for urinary tract infection (UTI) caused by extended-spectrum beta-lactamase (ESBL)-producing organisms are limited other than carbapenem. Accordingly, clinicians should investigate ...

A retrospective study of risk factors for stress urinary incontinence 1 year after delivery in multiparous women.

May 06, 2021

Stress urinary incontinence (SUI) is a common postpartum disorder. In this study, we aim to identify the risk factors for SUI in multiparous women 1 year after delivery.A retrospective cohort study w...

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