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OB/GYN General

P53 and TLR4 expression are prognostic markers informing progression free survival of advanced stage high grade serous ovarian cancer.

Dec 18, 2023

New prognostic biomarkers, and bio-signatures, are urgently needed to facilitate a precision medicine-based approach to more effectively treat patients with high-grade serous ovarian cancer (HGSC). In...

Which transfer day results in the highest live birth rate for PCOS patients undergoing in vitro fertilization?

Dec 18, 2023

Polycystic ovary syndrome (PCOS) has unusual levels of hormones. The hormone receptors in the endometrium have a hostile effect and make the microenvironment unfavorable for embryo implantation. The u...

Synthesis of melampomagnolide B derivatives as potential anti-Triple Negative Breast Cancer agents.

Dec 18, 2023

Triple-negative breast cancer (TNBC) is the most malignant and aggressive subtype of breast cancer. Currently, the treatment options to TNBC are limited and the discovery of new drugs and novel therap...

Pelvic floor and sexual function 3 years after hysterectomy - A prospective cohort study.

Dec 11, 2023

Long term effects after hysterectomy, such as a worsening of pelvic floor and sexual function, have been studied with diverse results. Therefore, we investigated the long-term effects of hysterectomy ...

Investigation of intradetrusor onabotulinum toxin A efficacy and safety in older adults with urge urinary incontinence.

Dec 11, 2023

Intradetrusor onabotulinum toxin A (BTX-A) has been demonstrated to be an effective treatment option for overactive bladder (OAB). However, concerns about frailty and frequent injections may deter its...

Abortion restrictions and medical residency applications.

Dec 11, 2023

Residency selection is a challenging process for medical students, one further complicated in the USA by the recent () decision over-ruling the federal right to abortion. We surveyed medical students...

Maternal treatment with selective serotonin reuptake inhibitors during pregnancy and delayed neonatal adaptation: a population-based cohort study.

Dec 11, 2023

Selective serotonin reuptake inhibitor (SSRI) use is common in pregnancy. It is associated with delayed neonatal adaptation. Most previous studies have not adjusted for the severity of maternal mental...

LncRNA HCP5 Facilitates the Progression of Ovarian Cancer by Interacting with the PTBP1 Protein.

Dec 11, 2023

Ovarian cancer (OC) is a major gynecological malignancy with an annually increasing morbidity that poses a significant threat to the health of women worldwide. Most OC patients are diagnosed at an adv...

Multi-Organ Increase in Norepinephrine Levels after Central Leptin Administration and Diet-Induced Obesity.

Dec 11, 2023

Autonomic innervation is important to regulate homeostasis in every organ of the body. The sympathetic nervous system controls several organs associated with metabolism and reproduction, including adi...

Prevalence, diagnostic delay and economic burden of endometriosis and its impact on quality of life: results from an Eastern Mediterranean population.

Dec 11, 2023

There are limited data on endometriosis from the Eastern Mediterranean region. This study for the first time estimates the prevalence and impact of endometriosis on women in Northern Cyprus, an under-...

The Financial Relationship Between the Medical Industry and Residency Leadership in OB/GYN and Urology.

Dec 11, 2023

Industry payments to physicians exceed millions of dollars. Payments can influence physicians' practices and potentially impact trainees. To examine the magnitude of industry payments to obstetrics ...

Learning Pelvic Anatomy and Pathology Through Drawing: An Interactive Session in the Obstetrics and Gynecology Clerkship.

Dec 11, 2023

Within undergraduate medical education, there is a gap between students' understanding of anatomy and application of that knowledge within surgical specialties. The integration of drawing, in conjunct...

Long time consequences after STARR procedure: Report of 15 years experience and medico-legal perspective.

Dec 04, 2023

Stapled transanal rectal resection is the most surgical procedure used for obstructed defecation syndrome, rectal prolapse, rectocele and rectal intussusception worldwide. The aim of this study is to ...

Comparison of Tumor Binding Across Tumor Types and Cell Lines to Support Free Drug Considerations for Oncology Drug Discovery.

Dec 04, 2023

Tumor binding is an important parameter to derive unbound tumor concentration to explore pharmacokinetics (PK) and pharmacodynamics (PD) relationships for oncology disease targets. Tumor binding was e...

The senescent mesothelial matrix accentuates colonization by ovarian cancer cells.

Dec 04, 2023

Ovarian cancer is amongst the most morbid of gynecological malignancies due to its diagnosis at an advanced stage, a transcoelomic mode of metastasis, and rapid transition to chemotherapeutic resistan...

Embryo Condition Media Collected from Polycystic Ovary Syndrome Patients with Abdominal Obesity Can Increase The Decidualization Potential of Healthy Endometrial Stromal Cells.

Dec 04, 2023

Polycystic ovary syndrome (PCOS) is a common endocrinological disorder associated with abdominal obesity (AO) and some reproductive complications including low pregnancy rate. Embryo-endometrium cross...

Subcutaneous fat predicts bone metastasis in breast cancer: A novel multimodality-based deep learning model.

Dec 04, 2023

This study explores a deep learning (DL) approach to predicting bone metastases in breast cancer (BC) patients using clinical information, such as the fat index, and features like Computed Tomography ...

Association of molecular subtypes and treatment with survival in invasive micropapillary breast cancer: an analysis of the Surveillance, Epidemiology, and End Results database.

Dec 04, 2023

This study aims to examine the features, treatments, and survival of invasive micropapillary carcinoma (IMPC) according to different molecular subtypes.In this cohort study, data between 2010 and 2018...

Perception and Comfort with Endometriosis Management Among OB/GYN Residents.

Dec 04, 2023

The diagnosis of endometriosis often takes several years, delaying appropriate care while patients suffer from pelvic pain, dysmenorrhea, and dyspareunia. Understanding whether residents in obstetrics...

Shaping the future of OB/GYN ultrasound training.

Dec 04, 2023

The pivotal role of ultrasound (US) in OB/GYN (Obstetric/Gynecological) practice is indisputable. Ultrasound is not merely a tool in the diagnostic process but a powerful asset in patient management a...

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