Apr 29, 2021

Neutropenia and diarrhoea are common and potentially serious adverse events associated with abemaciclib in advanced breast cancer (ABC), and the risk factors have been minimally explored. The study ai...

Apr 29, 2021

MicroRNAs play an irreplaceable role in gene expression regulation. Upregulation of several miRNAs increases the risk of invasion and metastasis of breast cancer cells. An oncogenic miRNA, miR-21, is ...

Apr 29, 2021

We sought to assess the effect of an educational intervention, based on DenseBreast-info.org website content, on women's healthcare provider knowledge of breast density, its risk and screening implica...

Apr 28, 2021

WEDNESDAY, April 28, 2021 (HealthDay News) -- Failure to rescue from severe maternal morbidity contributes to more than half of the threefold difference in maternal mortality between Black women and W...

Apr 26, 2021

Kidney intercalated cells are involved in acid-base homeostasis via vacuolar ATPase expression. Here we report six human intercalated cell subtypes, including hybrid principal-intercalated cells ident...

Apr 26, 2021

Postoperative urinary retention is common following female pelvic reconstructive surgery. Alpha receptor antagonists can improve dysfunctional voiding by relaxing the bladder outlet, and may be effect...

Apr 26, 2021

Prenatal fine particulate matter (PM) exposure has been associated with impaired offspring neurodevelopment; however, the association of PM exposure during preconception with offspring's neurodevelopm...

Apr 26, 2021

Veliparib (ABT-888) is a poly (ADP-ribose) polymerase (PARP) inhibitor in development for treatment of high-grade ovarian cancer or BRCA-mutated breast cancer in combination with carboplatin and pacli...

Apr 26, 2021

Despite many attempts to treat ovarian cancer, 13,940 individuals perish annually due to this disease worldwide. Chemotherapy is the main approach to ovarian cancer treatment, but the development of d...

Apr 26, 2021

Ovarian cancer (OC) is a gynecological malignancy with a poor prognosis and low survival rate. E2F2 is a transcription activator that plays an indispensable role in cell proliferation and cell cycle p...

Apr 26, 2021

An increased number of highly active regulatory T cells (Tregs) and macrophages has been found in peritoneal fluid from women with endometriosis. Here, we show that the level of Tregs-derived soluble ...

Apr 26, 2021

What are the genetic causes of oocyte maturation defects?A homozygous splicing variant (c.788 + 3A>G) in TATA-box binding protein like 2 (TBPL2) was identified as a contributory genetic factor ...

Apr 26, 2021

Natural product produced by plants has been the backbone for numerous anticancer agents. In the present work, natural bioactive thymol based 1,2,3-triazole hybrids have been synthesized and evaluated ...

Apr 26, 2021

Extracellular vesicles (EVs) are micro and nanoscale packages that circulate in all bodily fluids and play an important role in intercellular communication by shuttling biomolecules to nearby and dist...

Apr 23, 2021

Continued monitoring is critical, officials say Preliminary data from a U.S. CDC Covid-19 mRNA vaccine safety study show no obvious safety signals in close to 36,000 women vaccinated during pregnancy...

Apr 23, 2021

International study confirms link to worse outcomes Having Covid-19 during pregnancy was associated with worse outcomes, such as maternal mortality, preeclampsia, and preterm birth, in an internati...

Apr 22, 2021

Evidence regarding the impact of giant prostate volume (PV) on outcome after radical prostatectomy (RP) is controversial with a lack of evidence on the impact of PV on health-related quality of life (...

Apr 22, 2021

The aim of the study was to evaluate the genetic affinity of uropathogenic E. coli cultures (UPEC) and to identify the major types of extended spectrum beta-lactamases (ESBL) found among nosocomial is...

Apr 22, 2021

 This study aimed to assess the use of a standardized prenatal genetic testing educational video and its effects on patient uptake of prenatal testing, patient knowledge, decisional conflict, and de...

Apr 22, 2021

 Limited data are available on the outcome of infants born after uterus transplantation. Our aim was to describe the hospital course and laboratory findings in the first 2 months of life of the 12 i...