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OB/GYN General

Transcriptional Control of Parturition: Insights from Gene Regulation Studies in the Myometrium.

Apr 08, 2021

The onset of labour is a culmination of a series of highly coordinated and preparatory physiological events that take place throughout the gestational period. In order to produce the associated contra...

Parenting by mothers with intellectual disabilities in Poland: A photovoice study.

Apr 08, 2021

The diverse nature of parenting among people with intellectual disabilities can be affected by many factors, including stereotypes, experiencing social isolation, living in poverty, suffering from chr...

Vitamin D receptor upregulates lncRNA TOPORS-AS1 which inhibits the Wnt/β-catenin pathway and associates with favorable prognosis of ovarian cancer.

Apr 08, 2021

Long non-coding RNAs (lncRNAs) have important biological functions, but their involvement in ovarian cancer remains elusive. We analyzed high-throughput data to identify lncRNAs associated with ovaria...

Clinical Significance of Mesenteric Lymph Node Involvement in the Pattern of Liver Metastasis in Patients with Ovarian Cancer.

Apr 08, 2021

Mesenteric lymph node (MLN) involvement is often observed in ovarian cancer (OC) with rectosigmoid invasion. This study aimed to investigate the clinical significance of MLN involvement in the pattern...

The effect of platelet G proteins on platelet extravasation and tumor growth in the murine model of ovarian cancer.

Apr 08, 2021

We and other investigators have shown that platelets promote metastasis and the growth of tumors. Our rationale for conducting this study is that platelets' prometastatic and progrowth effects depend ...

Low basal serum testosterone level is detrimental to the embryo implantation in the patients with severe endometriosis.

Apr 08, 2021

Androgens have been reported to be associated with female fertility. The mean serum testosterone concentration in the patients with endometriosis was reported to be significantly lower than that witho...

Effects of CDKN2B-AS1 on cellular proliferation, invasion and AKT3 expression are attenuated by miR-424-5p in a model of ovarian endometriosis.

Apr 08, 2021

Endometriosis is a common and complicated gynaecologic disease. Long non-coding RNA CDKN2B-AS1 plays a crucial role in the development and progression of several cancers. Whether CDKN2B-AS1 contribute...

Antral follicle count and anti-Müllerian hormone to classify low-prognosis women under the POSEIDON criteria: a classification agreement study of over 9000 patients.

Apr 08, 2021

What is the agreement between antral follicle count (AFC) and anti-Müllerian hormone (AMH) levels when used to patient classification according to the Patient-Oriented Strategies Encompassing Individ...

Efficacy and reusability of mixed-phase TiO-ZnO nanocomposites for the removal of estrogenic effects of 17β-Estradiol and 17α-Ethinylestradiol from water.

Apr 08, 2021

Photocatalytic removal of estrogenic compounds (ECs), 17β-estradiol (E2), and 17α-ethinylestradiol (EE2) were assessed using a TiO-ZnO nanocomposite (NC) over a range of initial EC concentration (C;...

Prognostic Outcomes of Signet Ring Cell Carcinoma of the Breast.

Apr 08, 2021

Signet ring cell breast carcinoma (SRCBC) is a rare variant of invasive lobular carcinoma and there are no large series characterizing its long-term prognosis.The NCDB was queried from 2004-2016 to id...

Screening a prognosis-related target gene in patients with HER-2 positive breast cancer by bioinformatics analysis.

Apr 08, 2021

HER-2 positive breast cancer has a high risk of for relapse, metastasis and drug resistance, and is related to a poor prognosis. Thus, the study objective was to determine a target gene and explore th...

Feedback Focused: A Learner- and Teacher-Centered Curriculum to Improve the Feedback Exchange in the Obstetrics and Gynecology Clerkship.

Apr 08, 2021

Learners consistently report insufficient feedback, despite interventions to improve the quantity and quality of feedback. Effective feedback requires a dynamic partnership and a trusting relationship...

Management of Obesity During Pregnancy and Periconception: Case-Based Learning for OB/GYN Clerkships.

Apr 08, 2021

Medical students lack knowledge about the effects of bariatric surgery on pregnancy and medical management of obesity as it relates to reproductive health. Additionally, there is bias toward obese pat...

Universal Screening for Lynch Syndrome in Patients With Uterine Cancer

Apr 06, 2021

“Lynch syndrome (LS) is the most common hereditary cause of uterine cancer,” explains Daniel Spinosa, MD. “Understanding whether a uterine cancer is caused by LS or not has prognostic and therap...

Impact of Covid-19 pandemic on obstetric fistula repair program in Zimbabwe.

Apr 05, 2021

The advent of Covid-19 pandemic adversely affected many programs worldwide, public health, including programming for obstetric fistula were not spared. Obstetric fistula is an abnormal connection betw...

Percutaneous tibial nerve stimulation in patients with severe low anterior resection syndrome: randomized clinical trial.

Apr 05, 2021

Treatment of low anterior resection syndrome (LARS) is challenging. Percutaneous tibial nerve stimulation (PTNS) can improve select bowel disorders. An RCT was conducted to assess the efficacy of PTNS...

Should we perform cervix removal during hysterectomy for benign uterine disease? Clinical practice guidelines from the French College of Gynecologists and Obstetricians (CNGOF).

Apr 05, 2021

To provide guidelines from the French College of Obstetricians and Gynecologists (CNGOF), based on the best evidence available, concerning subtotal or total hysterectomy, for benign disease.The CNGOF ...

Non-classic splicing mutation in the CPLANE1 (C5orf42) gene cause Joubert syndrome in a fetus with severe craniocerebral dysplasia.

Apr 05, 2021

Joubert syndrome is a rare neurodevelopmental disorder characterized by clinical and genetic heterogeneity. The characteristic molar tooth sign, resulted from cerebellar vermis hypoplasia and midbrain...

Effect of Heparanase and Heparan Sulfate Chains in Hemostasis.

Apr 05, 2021

Heparanase, the only mammalian enzyme known to degrade heparan sulfate chains, affects the hemostatic system through several mechanisms. Along with the degrading effect, heparanase engenders release o...

The Role of PBK as a Potential Prognostic and Diagnostic Biomarker in Ovarian Cancer.

Apr 05, 2021

As one of the three malignant genital tumors, mortality in women with ovarian cancer is consistently high worldwide. It is of great importance to find prognostic markers for diagnosis and treatment o...

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