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OB/GYN General

EXPRESS: Does Non-Implanted Electrical Stimulation Reduce Post-Stroke Urinary or Fecal Incontinence? A Systematic Review with Meta-Analysis.

Mar 18, 2021

Urinary and fecal incontinence are disabling impairments after stroke that can be clinically managed with electrical stimulation.The purpose of this systematic review was to determine the effectivenes...

A comparison of faecal incontinence scoring systems.

Mar 18, 2021

Questionnaires designed to score the severity of faecal incontinence (FI) are widely used to provide an evaluation of symptoms across settings, studies and time. The Pelvic Floor Disorders Consortium ...

Successful laparoscopy-assisted repair of a rectovaginal fistula after low anterior resection for rectal cancer: a report of two cases.

Mar 18, 2021

Rectovaginal fistula (RVF) after low anterior resection for rectal cancer is troublesome and refractory. Although various surgical procedures have been previously described, no definitive procedure ha...

Postpartum depression and anxiety: a community-based study on risk factors before, during and after pregnancy.

Mar 18, 2021

Depression and anxiety occur frequently postpartum, calling for early detection and treatment. Evidence on risk factors may support early detection, but is inconclusive. Our aim was to identify risk f...

Poly (ADP-ribose) polymerase (PARP) as target for the treatment of epithelial ovarian cancer: what to know.

Mar 18, 2021

Poly (ADP-ribose) polymerase (PARP) inhibitors are being developed in maintenance and recurrence treatment settings of epithelial ovarian cancers (EOCs) with BRCA 1-2 genes mutation. PARP inhibitors a...

The results of multigene panel sequencing in Slovak HBOC families.

Mar 18, 2021

Hereditary breast and ovarian cancer (HBOC) is primarily associated with mutations in the BRCA1/2 genes. However, causal variants in other high, moderate, and low penetrance genes proportionally incre...

Non-contrast MRI can accurately characterize adnexal masses: a retrospective study.

Mar 18, 2021

To determine the accuracy of interpretation of a non-contrast MRI protocol in characterizing adnexal masses.Two hundred ninety-one patients (350 adnexal masses) who underwent gynecological MRI at our ...

Fennel (Foeniculum vulgare Miller) for the management of menopausal women's health: A systematic review and meta-analysis.

Mar 18, 2021

This review aimed to evaluate the current evidence on the effectiveness and safety of fennel (Foeniculum vulgare Miller) for managing menopausal women's health. Fourteen databases were searched. We in...

E3 ubiquitin ligase TRIM24 deficiency promotes NLRP3/Caspase-1/IL-1β-mediated pyroptosis in endometriosis.

Mar 18, 2021

Endometriosis is an inflammation-dependent disease which shares similarities with malignant tumors including attachment and infiltration. Tripartite motif containing 24 (TRIM24) has been illustrated i...

How did women with breast cancer experience the first wave of the COVID-19 pandemic? A qualitative study.

Mar 18, 2021

The ongoing COVID-19 global pandemic is a stressful experience that is particularly likely to negatively affect cancer patients. The goal of this qualitative study was to explore how breast cancer pat...

Factors Influencing Mammography Uptake Following a Screening Intervention among Asian American Women: A Systematic Review.

Mar 18, 2021

Asian American women, both immigrant and US-born, are known to have low mammography screening rates. To reduce health disparities and address community health needs, we undertook a systematic review t...

Cross-Resistance and the Mechanisms of Cephalosporin-Resistant Bacteria in Urinary Tract Infections Isolated in Indonesia.

Mar 15, 2021

Urinary tract infection (UTI) by antibiotic-resistant strains has become increasingly problematic, with trends that differ from country to country. This study examined cross-resistance and the mechani...

First Evidence for Colonizing of Acanthamoeba T4 Genotype in Urinary Tracts of Patients with Recurrent Urinary Tract Infections.

Mar 15, 2021

Limited evidence about the presence of Acanthamoeba spp. in urine specimens collected from urinary catheters of the patients in the intensive care units persuaded our study. No evidence has been found...

Biomechanics of the urinary bladder: spontaneous contraction activity and micromotions related to accommodation.

Mar 15, 2021

Knowledge of the fundamental properties of the urinary bladder is required to better understand its pathological conditions. Research on the passive and active properties of the bladder during stretch...

Platelet counts during normal pregnancies and pregnancies complicated with hypertensive disorders.

Mar 15, 2021

To determine the trajectories of platelet counts and the prevalence of gestational thrombocytopenia (<150 × 10/L) during normal pregnancies and pregnancies with complications, such as hypertensi...

Prenatal exposure to bisphenols affects pregnancy outcomes and offspring development in rats.

Mar 15, 2021

The objective of this study was to evaluate the effects of gestational exposure to low doses of bisphenol A (BPA), bisphenol S (BPS), and bisphenol F (BPF) on pregnancy outcomes and offspring developm...

Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors.

Mar 15, 2021

Targeting cell division by chemotherapy is a highly effective strategy to treat a wide range of cancers. However, there are limitations of many standard-of-care chemotherapies: undesirable drug toxici...

Y box binding protein 1 inhibition as a targeted therapy for ovarian cancer.

Mar 15, 2021

Y box binding protein 1 (YB-1) is a multifunctional protein associated with tumor progression and the emergence of treatment resistance (TR). Here, we report an azopodophyllotoxin small molecule, SU05...

Gene expression in the angiopoietin/TIE axis is altered in peripheral tissue of ovarian cancer patients: A prospective observational study.

Mar 15, 2021

Clinical studies suggest altered systemic vascular biology in cancer patients. We assessed expression patterns of endothelial activation- and vascular leakage-related genes in tumor as well as in tumo...

Mutations in the desert hedgehog (DHH) gene in the disorders of sexual differentiation and male infertility.

Mar 15, 2021

To identify the contribution of mutations in the Desert Hedgehog (DHH) gene to the disorders of sexual differentiation (DSD) and male infertility.The study included a total 430 subjects, including 47 ...

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