Advertisement

Ovarian Cancer

Conservative Vs Surgical Management of Atypical Endometrial Hyperplasia

Oct 04, 2022

Endometrial hyperplasia (EH), a known risk factor for endometrial cancer (EC), is an irregular proliferation of the adrenal glands increasing the gland to stroma ratio. If it manifests as atypical end...

Foreseeing Uterine Cancer’s Lymph Node Metastasis (LNM)

Oct 01, 2022

Histopathological criteria have a huge role in the preoperative categorization in endometrial carcinoma (EC). Due to the danger of lymph node metastasis (LNM), the diagnostic performance is moderate. ...

Feasibility of Adjuvant Radiation Therapy to Treat Gynecological Cancer

Oct 01, 2022

Endometrial cancer is a widely recognized female threat. It usually affects around 40,000 women every year. Numerous prospective arbitrary trials have been published. However, despite that, there stil...

MetS Tied to Poor Prognosis in Some Uterine Cancers

Sep 19, 2022

Metabolic syndrome was tied closely to poor prognosis among patients with endometrial cancer, according to a study published in Frontiers in Endocrinology. For the retrospective study—conducted at a...

Patients Undergoing Gynecologic Cancer Surgery Face Insurance-Based Disparities and Financial Toxicity

Sep 14, 2022

For a study, researchers sought to assess the association between insurance status and clinical and financial outcomes and financial toxicity (FT) risk among inpatients receiving gynecologic cancer re...

Financial Toxicity in Gynecologic Cancers: Patient-Reported Drivers

Sep 12, 2022

For a study, researchers sought to comprehend the effects that treatment-related financial burden has on gynecologic cancer patients and to pinpoint areas that may be targeted for treatments to lessen...

Uterine Carcinosarcoma: Combined Chemotherapy & EBRT

Sep 12, 2022

With stage, I to IV uterine carcinosarcoma patients are treated with surgery followed by adjuvant chemotherapy alone, radiation therapy alone, or a combination of chemotherapy and radiation therapy. F...

Financial Toxicity Has ‘Profound Impact’ in Gynecologic Oncology

Jun 13, 2022

Patients undergoing surgery for gynecologic cancer, particularly those without insurance, experience a significant risk for financial toxicity, according to findings published in Gynecologic Oncology....

Pyroptosis-Related Genes May Have a Prominent Role in Uterine Cancer

Jun 07, 2022

The linguistic origin of pyroptosis is Greek—pyro meaning fire and ptosis meaning falling or dropped. In science, the term pyroptosis appropriately refers to a highly inflammatory pathway toward reg...

Molecular Classification Can Indicate Survival in Gynecologic Cancer Recurrence

Apr 28, 2022

Molecular classification served as a significant marker of survival following endometrial cancer (EC) recurrence, with patterns of recurrence that varied based on molecular subgroups, according to fin...

Microbiome Differs in Black Vs White Women With Gynecologic Cancer

Apr 27, 2022

Black women experience higher mortality from endometrial cancer (EC) than White women, according to published data, and potential reasons for this disparity include increased rates of obesity and more...

How tamoxifen (sometimes) induces uterine cancer: affecting the PI3K pathway

Dec 15, 2021

Long-term use of tamoxifen is associated with an increased risk for the development of uterine cancer. New research shows that tamoxifen directly activates a signaling pathway (PIK3) that is a well-kn...

Updated results from RxPONDER confirm importance of menopausal status on treatment efficacy

Dec 14, 2021

The phase 3 RxPONDER trial evaluated the benefit of adjuvant chemotherapy followed by endocrine therapy in women with HR-positive, HER2-negative, early-stage breast cancer and 1–3 positive nodes. Up...

Unmet Needs for Gynecologic Malignancy

Dec 14, 2021

There remains an “urgent need” for better therapies, as well as earlier diagnosis and earlier identification of recurrences, in endometrial cancer, according to the authors of a study published in...

Hsa_circ_0004712 downregulation attenuates ovarian cancer malignant development by targeting the miR-331-3p/FZD4 pathway.

Sep 13, 2021

Circular RNAs (circRNAs) are gradually reported to be implicated in the development of malignant tumors, including ovarian cancer (OC). This paper intended to explore the function and action mechanism...

Trends and age-period-cohort effects on mortality of the three major gynecologic cancers in China from 1990 to 2019: Cervical, ovarian and uterine cancer.

Sep 13, 2021

Gynecologic cancers seriously threaten women's life and health. This study aims to assess the long-term trends of mortality from the three major gynecologic cancers in China and to examine the age-, p...

REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps.

Sep 13, 2021

BRCA1/2 mutant tumor cells display an elevated mutation burden, the etiology of which remains unclear. Here, we report that these cells accumulate ssDNA gaps and spontaneous mutations during unperturb...

Associations of preoperative serum high-density lipoprotein cholesterol and low-density lipoprotein cholesterol levels with the prognosis of ovarian cancer.

Aug 30, 2021

The effect of serum lipids on ovarian cancer is controversial. We conducted this study to evaluate the prognostic value of preoperative plasma lipid profile in patients with ovarian cancer.The medical...

Clinical and pathological outcomes of risk-reducing salpingo-oophorectomy for Japanese women with hereditary breast and ovarian cancer.

Aug 30, 2021

To clarify the clinical as well as pathological outcomes in Japanese women with germline pathogenic BRCA1/2 variants who underwent risk-reducing salpingo-oophorectomy (RRSO).This prospective study exa...

[Treatment of advanced epithelial ovarian tumor. Hospital Italiano de Buenos Aires experience].

Aug 30, 2021

Ovarian cancer represents the third gynecological cancer in frequency in Argentina. There is a lack of information on this pathology in our country regarding the treatment and evolution of patients wh...

SUBSPECIALTIES

Advertisement