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Ovarian Cancer

High visceral fat-to-muscle ratio is an independent factor that predicts worse overall survival in patients with primary epithelial ovarian, fallopian tube, and peritoneal cancer.

Jan 23, 2023

The intra-abdominal cavity, surrounded by adipocytes, is the main metastatic site of epithelial ovarian, fallopian tube, and peritoneal cancer. Epidemiological and molecular studies have demonstrated ...

A comparison of synoptic reports and dictated reports to enhance and standardize surgical documentation and quality of care in epithelial ovarian cancer.

Jan 16, 2023

The purpose of this study is to assess the degree to which synoptic reports (SRs) and dictated reports (DRs) document elements of the Ovarian Cancer Pan-Canadian Standards Data Elements (OCPCDE) check...

Can circulating cell free DNA be a promising marker in ovarian cancer? - a genome-scale profiling study in a single institution.

Jan 16, 2023

Cell-free DNA (cfDNA) is emerging as a potential biomarker for the detection of ovarian cancer (OC). Recently, we reported a method based upon cfDNA whole-genome sequencing data including the nucleoso...

Prophylactic Salpingectomy during Hysterectomy for Benign Disease: A Prospective Study to Evaluate High-Grade Serous Ovarian Carcinoma Precursors.

Jan 09, 2023

Recent findings suggest that high-grade serous ovarian cancer can originate in the fallopian tube. Not only has that made the identification of precursor lesions pivotal in early detection and prevent...

Targeted Delivery of Sunitinib by MUC-1 Aptamer-Capped Magnetic Mesoporous Silica Nanoparticles.

Jan 09, 2023

Magnetic mesoporous silica nanoparticles (MMSNPs) are being widely investigated as multifunctional novel drug delivery systems (DDSs) and play an important role in targeted therapy. Here, magnetic cor...

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer.

Jan 02, 2023

Cancer antigen 125 (CA125) is one of the mucin family proteins and is a serum tumor marker for various tumors, such as ovarian cancer, endometrial cancer, pancreatic cancer, and bladder cancer, used t...

The prognosis predictive score around primary debulking surgery (PPSP) improves diagnostic efficacy in predicting the prognosis of ovarian cancer.

Jan 02, 2023

In recent years, the pretreatment inflammatory responses have proven to predict the prognosis, but no report exists analyzing the combined inflammatory response of the pre- and postsurgical treatment....

Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors.

Dec 19, 2022

Low-grade serous ovarian cancer (LGSOC) is a rare disease that occurs more frequently in younger women than those with high-grade disease. The current treatment is suboptimal and a better understandin...

Pretreatment Nutritional Status in Combination with Inflammation Affects Chemotherapy Interruption in Women with Ovarian, Fallopian Tube, and Peritoneal Cancer.

Dec 12, 2022

Discontinuing chemotherapy worsens cancer prognosis. This study aimed to investigate the relationship between nutritional status at the start of chemotherapy and chemotherapy discontinuation in patien...

Fertility Options for Patients With Gynecological Cancer

Nov 04, 2022

For patients with early-stage endometrial cancer (EC), standard treatment has been hysterectomy with bilateral salpingo-oophorectomy with lymphadenectomy, note the authors of a study published in ...

Immune Microenvironment Manipulation for Uterine Cancer

Oct 04, 2022

Studies show that endometrial cancer (EC) rates are increasing in younger people with obesity is a likely contributor to this observed proliferation because it raises estrogen production and adipokine...

Conservative Vs Surgical Management of Atypical Endometrial Hyperplasia

Oct 04, 2022

Endometrial hyperplasia (EH), a known risk factor for endometrial cancer (EC), is an irregular proliferation of the adrenal glands increasing the gland to stroma ratio. If it manifests as atypical end...

Foreseeing Uterine Cancer’s Lymph Node Metastasis (LNM)

Oct 01, 2022

Histopathological criteria have a huge role in the preoperative categorization in endometrial carcinoma (EC). Due to the danger of lymph node metastasis (LNM), the diagnostic performance is moderate. ...

Feasibility of Adjuvant Radiation Therapy to Treat Gynecological Cancer

Oct 01, 2022

Endometrial cancer is a widely recognized female threat. It usually affects around 40,000 women every year. Numerous prospective arbitrary trials have been published. However, despite that, there stil...

MetS Tied to Poor Prognosis in Some Uterine Cancers

Sep 19, 2022

Metabolic syndrome was tied closely to poor prognosis among patients with endometrial cancer, according to a study published in Frontiers in Endocrinology. For the retrospective study—conducted at a...

Patients Undergoing Gynecologic Cancer Surgery Face Insurance-Based Disparities and Financial Toxicity

Sep 14, 2022

For a study, researchers sought to assess the association between insurance status and clinical and financial outcomes and financial toxicity (FT) risk among inpatients receiving gynecologic cancer re...

Financial Toxicity in Gynecologic Cancers: Patient-Reported Drivers

Sep 12, 2022

For a study, researchers sought to comprehend the effects that treatment-related financial burden has on gynecologic cancer patients and to pinpoint areas that may be targeted for treatments to lessen...

Uterine Carcinosarcoma: Combined Chemotherapy & EBRT

Sep 12, 2022

With stage, I to IV uterine carcinosarcoma patients are treated with surgery followed by adjuvant chemotherapy alone, radiation therapy alone, or a combination of chemotherapy and radiation therapy. F...

Financial Toxicity Has ‘Profound Impact’ in Gynecologic Oncology

Jun 13, 2022

Patients undergoing surgery for gynecologic cancer, particularly those without insurance, experience a significant risk for financial toxicity, according to findings published in Gynecologic Oncology....

Pyroptosis-Related Genes May Have a Prominent Role in Uterine Cancer

Jun 07, 2022

The linguistic origin of pyroptosis is Greek—pyro meaning fire and ptosis meaning falling or dropped. In science, the term pyroptosis appropriately refers to a highly inflammatory pathway toward reg...

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