Acute myeloid leukemia is characterized by uncontrolled proliferation of self-renewing myeloid progenitors accompanied by a differentiation arrest. PHF6 is a chromatin-binding protein mutate...
Zanubrutinib plus venetoclax delivered promising preliminary efficacy results in newly diagnosed CLL/SLL in participants with del(17p) and/or TP53 mutations....
The AUGMENT-101 trial in patients with in KMT2Ar leukemia has been stopped early because of revumenib encouraging anti-tumor activity....
Adding additional clinical and genetic information improved the performance of prognostic scores in secondary myelofibrosis, researchers in France report....
Personalized ddPCR monitoring of rare genetic alterations can help clinicians make timely treatment decisions for patients with leukemia, according to research....
This study aimed to assess the efficacy of dual T-cell suppression using individually tailored doses of antithymocyte globulin (ATG) and attenuated dose of post-transplant cyclophosphamide (...
Angiogenesis is the determining factor during dental pulp regeneration. Six-twelve leukemia (STL) is identified as a key regulatory factor on the biological function of dental pulp stem cell...
Click here to read this study in JAMA. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inqu...
Research presented at the fourth European Congress Controversies in Leukemia and how this new information has changed the landscape for patients with acute myeloid leukemia. ...
An evaluation of allo-HSCT as a treatment for intermediate-risk acute myeloid leukemia and if allogeneic transplantation is necessary....
A summary of the updates made to the classifications for Acute Myeloid Leukemia from the World Health Organization and the International Consensus Classification of Myeloid and Lymphoid Neop...
Older adults with acute myeloid leukemia had improved survival and lower mortality for years after receiving allogeneic hematopoietic cell transplantation....
Patients with low-risk CLL selected to stop receiving specialized follow-up care had similar overall survival but fewer hospitalizations. ...
Studies on dasatinib-based low-intensity induction regimens and post-remission strategies are limited in China. Therefore, we conducted a single-center phase 2 trial in newly diagnosed adult...
Recent studies have found that circular RNAs (circRNAs) play important roles in tumorigenesis. This study aimed to determine the function and potential mechanisms of hsa_circ_0001615 in esop...
Childhood, adolescent and young-adult (AYA) cancer survivors often experience health problems due to late or long-term effects of their cancer or the treatment thereof. The general populatio...
Chronic disseminated candidiasis (CDC) is a severe but rarely seen fungal infection presenting in patients with hematologic malignancies after a prolonged duration of neutropenia. A high ind...
The outcome of patients with acute promyelocytic leukemia (APL) has improved significantly since the introduction of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) as APL therapie...
Chronic myelogenous leukemia (CML) is a clonal hematologic malignancy of the myeloid lineage caused by the oncogenic BCR/ABL fusion protein that promotes CML cell proliferation and protects ...
Overexpressed pro-survival B-cell lymphoma-2 (BCL-2) family proteins BCL-2 and BCL-X can render tumor cells malignant. Leukemia drug venetoclax is currently the only approved selective BCL-2...
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