A panel of experts discusses the nuances of treating paroxysmal nocturnal hemoglobinuria in older patients, focusing on comorbidities and complications. Since 2007, complement-inhibiting drugs have enabled people with paroxysmal nocturnal...
Oncology / Hematology
RELEVANT ARTICLES IN Oncology / Hematology
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Disulfidptosis-related immune patterns predict prognosis and characterize the tumor microenvironment in oral squamous cell carcinoma.
Disulfidptosis-related immune patterns predict prognosis and characterize the tumor microenvironment in oral squamous cell carcinoma.
Establishing a prognostic risk model based on immunological and disulfidptosis signatures enables precise prognosis prediction of oral squamous cell carcinoma (OSCC).Differentially expressed immune and disulfidptosis genes were identified in OSCC and normal...
Nuclear ANLN regulates transcription initiation related Pol II clustering and target gene expression.
Nuclear ANLN regulates transcription initiation related Pol II clustering and target gene expression.
Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been fully understood. Here, we report a role of nuclear ANLN in gene...
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Bruton’s tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax.
Bruton’s tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax.
Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline combination chemoimmunotherapy, DLBCL carries persistently poor...
Patterns and variations of copy number alterations in acute myeloid leukemia: insights from the LeukAtlas database.
Patterns and variations of copy number alterations in acute myeloid leukemia: insights from the LeukAtlas database.
Recent pan-cancer analysis revealed the global pattern and potential aetiologies of copy number variation signatures in human cancers, particularly those derived from non-hematopoietic tissues. In sharp contrast, the generally low CNV burden in leukemia leaves the...
Determination of hematologic reference intervals for free-living King vultures (Sarcoramphus papa).
Determination of hematologic reference intervals for free-living King vultures (Sarcoramphus papa).
As obligate scavengers, New World vultures (Cathartiformes: Cathartidae) play a key role in carcass removal and disease control. Associated with this ecosystem service, vultures are exposed to the consumption of harmful substances such as poisons, heavy metals,...
Disulfidptosis-related immune patterns predict prognosis and characterize the tumor microenvironment in oral squamous cell carcinoma.
Disulfidptosis-related immune patterns predict prognosis and characterize the tumor microenvironment in oral squamous cell carcinoma.
Establishing a prognostic risk model based on immunological and disulfidptosis signatures enables precise prognosis prediction of oral squamous cell carcinoma (OSCC).Differentially expressed immune and disulfidptosis genes were identified in OSCC and normal...
Nuclear ANLN regulates transcription initiation related Pol II clustering and target gene expression.
Nuclear ANLN regulates transcription initiation related Pol II clustering and target gene expression.
Anillin (ANLN), a mitotic protein that regulates contractile ring assembly, has been reported as an oncoprotein. However, the function of ANLN in cancer cells, especially in the nucleus, has not been fully understood. Here, we report a role of nuclear ANLN in gene...
Bruton’s tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax.
Bruton’s tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax.
Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline combination chemoimmunotherapy, DLBCL carries persistently poor...
Patterns and variations of copy number alterations in acute myeloid leukemia: insights from the LeukAtlas database.
Patterns and variations of copy number alterations in acute myeloid leukemia: insights from the LeukAtlas database.
Recent pan-cancer analysis revealed the global pattern and potential aetiologies of copy number variation signatures in human cancers, particularly those derived from non-hematopoietic tissues. In sharp contrast, the generally low CNV burden in leukemia leaves the...
Determination of hematologic reference intervals for free-living King vultures (Sarcoramphus papa).
Determination of hematologic reference intervals for free-living King vultures (Sarcoramphus papa).
As obligate scavengers, New World vultures (Cathartiformes: Cathartidae) play a key role in carcass removal and disease control. Associated with this ecosystem service, vultures are exposed to the consumption of harmful substances such as poisons, heavy metals,...
CONDITION SPOTLIGHTS
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SABCS 2024
Physician’s Weekly-created content featuring key opinion leaders sharing their perspectives on eBC & mBC from different vantage points at SABCS 2024.
When Disaster Strikes: Preparing & Adapting to Meet Community Needs
When Disaster Strikes: Preparing & Adapting to Meet Community Needs
Preparedness, flexibility, and commitment to public education are critical to physicians' abilities to meet community needs in the face of disasters.
Q&A: Breaking Down Indemnification Clauses
Q&A: Breaking Down Indemnification Clauses
Dr. MedLaw answers your questions regarding medical law, breaking down indemnification clauses in this article in response to a physician's query.
Understanding Healthcare Hurdles Through Dual Perspectives
Understanding Healthcare Hurdles Through Dual Perspectives
Healthcare professionals and patients share perspectives on US healthcare hurdles, highlighting the need to improve affordability and care.
CME / CE
In Multifocal HCC, Survival Better With Liver Resection Vs Tumor Ablation
This course discusses the overall survival with liver resection versus tumor ablation in patients with multifocal hepatocellular carcinoma
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Your Online Presence Could Be Your Liability: A Doctor’s Guide to Social Media Risks
Your Online Presence Could Be Your Liability: A Doctor’s Guide to Social Media Risks
Employing caution and professionalism, doctors can reap social media benefits while avoiding social media risks, protecting their reputations and patient trust.
Transfusion Medicine in 2025: Challenges, Innovations, & the Clinicians’ Role in Driving Blood Donation
Transfusion Medicine in 2025: Challenges, Innovations, & the Clinicians’ Role in Driving Blood Donation
ADRP Advisory Board Member Amanda Hess discusses advances in transfusion medicine, challenges blood centers face, and how clinicians can boost blood donation.
Healthcare’s Financial Fault Line: How to Navigate Patient Debt for Improved Health Outcomes
Healthcare’s Financial Fault Line: How to Navigate Patient Debt for Improved Health Outcomes
Rising patient debt strains the US healthcare system, but improving financial assistance, revenue management, and patient engagement can help reduce the burden.
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