Maintenance Olaparib Rechallenge in Platinum-Sensitive Relapsed Ovarian Cancer
Bookmark1. Median PFS was improved in the olaparib arm vs placebo, with an HR 0.57 in the BRCAm...
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Oncology
Adenocarcinoma is the most prevalent lung cancer subtype and has a greater incidence rate in males than females
Bookmark1. The second greatest burden of lung cancer worldwide is attributed to squamous cell...
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Camrelizumab plus rivoceranib superior to sorafenib for treatment of unresectable hepatocellular carcinoma
Bookmark1. Patients in the camrelizumab-rivoceranib group reported significantly greater...
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Breast-conserving surgery is an appropriate procedure for centrally located breast cancer
Bookmark1. Patients with centrally located breast cancer (CLBC) had higher breast cancer-specific...
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Adjuvant everolimus does not improve survival for patients with resected renal cell carcinoma
Bookmark1. Recurrence-free survival was significantly different between the adjuvant everolimus...
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Atezolizumab, Vemurafenib, and Cobimetinib in Melanoma With CNS Metastases
Bookmark1. Intracranial objective response rate was 42% in the BRAF V600 mutation-positive cohort...
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Computer-aided detection does not improve neoplasm detection with colonoscopy
Bookmark1. The GI-Genius neural network system did not improve the rate of detecting advanced...
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Younger onset of non-alcoholic fatty liver disease associated with greater cancer risk
Bookmark1. In this case-control study, younger age of onset of non-alcoholic fatty liver disease...
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Prophylactic Radiation Therapy for High-Risk Asymptomatic Bone Metastases
Bookmark1. The hazard ratio of skeletal-related events in patients treated with radiation compared...
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Omission of axilla surgery is non-inferior to sentinel lymph node biopsy in female patients with small breast cancers and clinically negative axillary lymph nodes
Bookmark1. 5-year distant disease-free survival was comparable between both groups. 2. 5-year...
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Tumor Treating Fields vs Standard Therapy in Treatment-Resistant Metastatic NSCLC
Bookmark1. The median OS was 13.2 months with TTFields arm vs 9.9 months with standard arm, with...
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Cetuximab maintenance therapy may be effective for RAS Wild-type metastatic colorectal cancer
Bookmark1. This phase 2 randomized clinical trial found that patients with metastatic colorectal...
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Adjuvant nivolumab may be promising for treatment of completely resected Merkel cell carcinoma
Bookmark1. Disease-free survival at 24 months was 84% in the nivolumab group compared to 73% in...
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Atezolizumab is a potentially effective treatment option for patients with alveolar soft part sarcoma
Bookmark1. 37% of study patients had an objective response to treatment with atezolizumab. 2....
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Patritumab Deruxtecan in EGFR-mutated NSCLC post EGFR TKI and Chemotherapy
Bookmark1. The objective response rate was 29.8% (1% complete response, 66% partial response) with...
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Nivolumab/Ipilimumab vs Nivolumab Alone in Advanced Cancers Other Than Melanoma
Bookmark1. Pooled overall survival and progression-free survival HR were found to be 0.95 and 0.88...
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Vitamin D3 supplementation may improve relapse-free survival for certain digestive tract cancers
Bookmark1. This post-hoc analysis of the AMATERASU randomized clinical trial found that, for...
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Survivors of childhood cancer are less active than their peers
Bookmark1. In a cross-sectional study, adolescent survivors of childhood cancers were more...
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Lisocabtagene maraleucel may induce remission in relapsed chronic lymphocytic leukemia (CLL)
Bookmark1. Complete response or remission was reported in 18% of patients who received a single...
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Cancer mortality after low dose exposure to ionising radiation in workers
Bookmark1. The risk of mortality from solid cancer, lagged by 10 years, is estimated to be...
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