Neoadjuvant FOLFOX compared to Chemoradiotherapy in Locally Advanced Rectal Cancer
Bookmark1. Patients who were randomized to neoadjuvant FOLFOX vs standard chemoradiation had...
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Oncology
ChatGPT accurately selects imaging modality for breast cancer screening and pain assessment
Bookmark1. In this clinical decision support study, the performance of the Chat Generative...
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COVID-19 associated with delayed cancer diagnoses and increased cancer mortality in Alberta
Bookmark1. This study found that healthcare disruption during the COVID-19 pandemic led to...
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IBD Plus Colectomy Increases Rectal Cancer Risk Up to 10-Fold
Patients with IBD and subtotal colectomy experienced a higher risk for rectal cancer compared with...
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Overall Survival Improved with Adjuvant Osimertinib in Resected EGFR-Mutated NSCLC
Bookmark1. The 5-year overall survival had a hazard ratio of 0.49, and this benefit was generally...
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Trastuzumab deruxtecan superior to physician’s choice treatment in patients with metastatic HER2-positive breast cancer
Bookmark1. Progression-free survival was greater in the trastuzumab group compared to standard...
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Pembrolizumab plus gemcitabine and cisplatin improves survival in advanced biliary tract cancer
Bookmark1. Median overall survival was greater in the pembrolizumab group compared to the control...
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‘Inform and Empower’ Patients on PrEP to Start HPV Vaccine Series
Incorporating HPV vaccination into PrEP services may increase the number of patients who receive...
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Gene Expression Profiles Predict Benefit From Neoadjuvant Immune Checkpoint Therapy in Triple-Negative Breast Cancer
The GeparNuevo trial sheds light on the role of RNA expression from peripheral immune cells in...
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Olanzapine as an adjunct to standard antiemtic therapy for patients receiving chemotherapy
Bookmark1. The addition of olanzapine to standard antiemetic therapy had a significantly higher...
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Zolbetuximab improves survival in patients with advanced or metastatic gastric adenocarcinoma
Bookmark1. Median progression-free survival in zolbetuximab group was greater than in the placebo...
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Surgical removal of tonsils and adenoids may slightly increase risk of cancer development
Bookmark1. Surgical removal of the tonsils and adenoids was associated with slightly increased...
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Characterization of cancer development risk following pediatric radiation exposure from computed tomography
BookmarkEvidence rating level: 3 (Average) 1. Exposure to a higher cumulative number of pediatric...
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Quizartinib improves overall median survival in patients with acute myeloid leukemia
Bookmark1. Overall survival in the quizartinib group was 31.9 months compared to 15.1 months in...
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WB: Chemoimmunotherapy Not Linked With Overall Benefit Vs. Immunotherapy Alone
Chemoimmunotherapy was linked with no survival advantage versus immunotherapy alone in advanced...
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High body mass index associated with increased risk of gastrointestinal cancers
Bookmark1. Individuals with an overweight or obese body mass index (BMI) are at increased risk for...
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Tumour stroma ratio predicts prognosis and PD-L1 expression in hepatocellular carcinoma
Bookmark1. The tumour stroma ratio (TSR) is a prognostic biomarker for predicting recurrence-free...
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Temporary interruption of endocrine therapy in women with endocrine-responsive breast cancer did not affect cancer outcomes
Bookmark1. The 3-year incidence of breast cancer in the study group was 8.9% compared to 9.2% in...
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Trifluridine–Tipiracil and Bevacizumab Improves Survival in Metastatic Pretreated Colorectal Cancer
Bookmark1. The median overall survival was 10.8 months in the combination group (FTD–TPI +...
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Venetoclax in addition to ibrutinib effective as a treatment for chronic lymphocytic leukemia
Bookmark1. High genetic risk participants with chronic lymphocytic leukemia (CLL) taking...
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