CAR-T Cell Therapy for Relapsed or Refractory High-Risk Neuroblastoma
1. GD2-CART01 infusion had an overall response of 63% of patients (33% complete response) with a...
Read More
Oncology
Belzutifan plus cabozantinib for immunotherapy pre-treated advanced renal cell carcinoma
1.The objective response rate was 30.8% with the majority attributing to partial response. 2. Most...
Read More
Physical activity may improve disease-free survival following resection of stage III colon cancer
1. In this cohort study, physical activity was associated with improved disease-free survival in...
Read More
Programmed death-ligand 1 copy number alterations may provide an additional predictive measure for response to immunotherapy in non-small cell lung cancer
1. Programmed death-ligand 1 copy number loss was identified as an independent risk factor for the...
Read More
Preexisting heart failure associated with lower use of anthracyclines and chemotherapy
1. In this longitudinal cohort study of 30 728 patients with diffuse large-B-cell lymphoma,...
Read More
Reminiscence therapy improves mental health outcomes in cancer survivors
1. In this systematic review and meta-analysis, cancer survivors who received reminiscence therapy...
Read More
Disulfiram is not effective as an adjunctive therapy to standard chemotherapy for glioblastoma
1. Adding disulfiram and copper to standard alkylating chemotherapy for glioblastoma (GB) was not...
Read More
Helicobacter pylori, Homologous Recombination Genes, and Risk of Gastric Cancer
1. The following genes had statistically significant increased odds ratio of gastric cancer;...
Read More
Hyperfractionated radiotherapy reduces complication rates compared to standard fractionation for locally advanced nasopharyngeal carcinoma
1. Fewer patients in the hyperfractionation group reported grade 3 or worse late radiation-induced...
Read More
United States patients receive subcutaneous fluids less frequently than intravenous fluids when compared to Canadian patients
1. Canadian patients receive subcutaneous administration of medications and/or fluids more...
Read More
Alternative Dose Regimens of Exemestane in Postmenopausal Women with Breast Cancer
1. Through the reduction in serum estradiol, there was noninferiority between the 3-times-weekly...
Read More
Adenoma detection rate is inversely associated with post-colonoscopy colorectal cancer risk
1. In this prospective cohort study, the adenoma detection rate (ADR) was inversely associated...
Read More
Nivolumab plus ipilimumab does not improve survival in post-nephrectomy patients with renal cell carcinoma
1. Disease-free survival in the placebo group was 50.7 months and was never reached in the...
Read More
Active monitoring, prostatectomy, and radiotherapy as treatment options for localized prostate cancer result in similar prostate-cancer-mortality
1. Localized prostate cancer mortality remains similar between groups receiving prostatectomy,...
Read More
Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors
1. There is a 71% lower risk of disease progression or death in the nirogacestat group than in the...
Read More
Sotorasib superior to docetaxel for treatment of KRASG12C-positive non-small-cell lung cancer
1. Patients allocated to the sotorasib group reported increased progression-free survival compared...
Read More
Addition of PD-L1 inhibitor may improve outcomes in neoadjuvant therapy for esophageal cancer
1. In this phase II randomized clinical trial, treatment of patients with locally advanced...
Read More
Combination therapy with alisterib and fulvestrant may be clinically advantageous in the treatment of endocrine-resistant advanced breast cancer
1. Compared to alisertib alone, adding alisertib to fulvestrant did not increase objective tumour...
Read More
Maternity genitourinary tract infections associated with increased offspring leukemia risk in Danish cohort
1. In a Danish cohort, maternal genitourinary tract infection during pregnancy was associated with...
Read More
Paid-sick-leave mandates contribute to increased cancer screening in the United States
1. Mandated and available paid-sick-leave resulted in increased colorectal and breast cancer...
Read More