Characterization of prognostic markers of residual neoplastic disease following hysterectomy
1. Prognostic markers of residual disease following a loop electrosurgical excision procedure for...
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Oncology
Direct-acting antiviral agents significantly lower Hepatitis C related mortality and cancer risk
1. In this retrospective cohort study, adult patients with hepatitis C virus (HCV) infection...
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Tumor-infiltrating lymphocyte therapy compared to ipilimumab in advanced melanoma
1 .Tumor-infiltrating lymphocytes therapy shows improvements in PFS when compared to ipilimumab 2....
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Positive prostate MRI and targeted biopsy reduce the detection of clinically insignificant prostate cancer
1. Fewer instances of clinically insignificant prostate cancer were identified in an experimental...
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PD-1 antibody plus chemotherapy in low PD-L1 expressing esophageal squamous cell carcinoma
1. The post-hoc analysis of JUPITER-06 showed the superiority of adding toripalimab (PD-1...
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The majority of FDA-approved drug trials recruit from low- and middle-income countries
1. This study found that a high proportion of Food and Drug Administration (FDA) drug trials...
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Overall survival with triplet therapy in BRAF V600 mutation-positive advanced melanoma
1. OS in triplet combination therapy (atezolizumab, vemurafenib, and cobimetinib) while numerally...
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Autologous tumour lysate-loaded dendritic cell vaccine in conjunction with standard treatment for glioblastoma may increase overall survival
1. Patients receiving autologous tumour lysate-loaded dendritic cell vaccine (DCVax-L) had a 20%...
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Preoperative biliary draining prior to pancreaticoduodenectomy not associated with increased complication risk
1. In patients with a pancreatic or periampullary tumour undergoing pancreaticoduodenectomy (PD),...
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Adding autologous tumor lysate-loaded dendritic cell vaccination to standard of care associated with clinical improvement in overall survival for patients with newly diagnosed and recurrent glioblastoma
1. In this phase 3 nonrandomized controlled trial, among 331 patients, patients with newly...
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Characterization of negative outcomes associated with same-day cancellation of cancer surgeries
1. This retrospective study found that patients who experienced a same-day cancellation of their...
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Association of quality and technology with patient mobility for colorectal cancer surgery
1. Around 30% of colorectal patients travel beyond their closest hospital site to undergo a...
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First-line treatment with immune checkpoint inhibitor rather than BRAF and MEK leads to improved survival
1. Starting treatment with nivolumab/ipilimumab rather than dabrafenib/trametinib resulted in an...
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Second-line immunosuppression associated with worse outcomes for immune-related adverse events in melanoma
1. Median overall survival was longer in patients receiving steroid-only treatment for adverse...
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United States-based chemotherapy regimen for Ewing sarcoma is more effective and safer than the standard European regimen
1. The United States regimen had greater event-free survival and less associated febrile...
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The experience of spirituality may positively impact the lives of terminal cancer patients
1. In this study, individuals were found to experience peace at the end of life through...
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Variation in prostate cancer screening rates associated with subsequent metastatic prostate cancer incidence
1. A retrospective analysis demonstrated that prostate-specific antigen (PSA) screening has...
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Continued enzalutamide after progression of metastatic prostate cancer improves progression-free survival
1. The median progression-free survival was higher in the enzalutamide vs the placebo group (9.5...
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Adjuvant pembrolizumab improved distant-metastasis free survival and lowered risk of recurrence in melanoma patients
1. In the pembrolizumab arm, distant metastasis-free survival was significantly improved and the...
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Polycystic ovarian syndrome is associated with an increased risk of pancreatic cancer
1. Polycystic ovarian syndrome (PCOS) diagnosis puts women at 1.9 times higher risk of pancreatic...
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