Overall survival with triplet therapy in BRAF V600 mutation-positive advanced melanoma
1. OS in triplet combination therapy (atezolizumab, vemurafenib, and cobimetinib) while numerally...
Read More
Oncology
Autologous tumour lysate-loaded dendritic cell vaccine in conjunction with standard treatment for glioblastoma may increase overall survival
1. Patients receiving autologous tumour lysate-loaded dendritic cell vaccine (DCVax-L) had a 20%...
Read More
Preoperative biliary draining prior to pancreaticoduodenectomy not associated with increased complication risk
1. In patients with a pancreatic or periampullary tumour undergoing pancreaticoduodenectomy (PD),...
Read More
Adding autologous tumor lysate-loaded dendritic cell vaccination to standard of care associated with clinical improvement in overall survival for patients with newly diagnosed and recurrent glioblastoma
1. In this phase 3 nonrandomized controlled trial, among 331 patients, patients with newly...
Read More
Characterization of negative outcomes associated with same-day cancellation of cancer surgeries
1. This retrospective study found that patients who experienced a same-day cancellation of their...
Read More
Association of quality and technology with patient mobility for colorectal cancer surgery
1. Around 30% of colorectal patients travel beyond their closest hospital site to undergo a...
Read More
First-line treatment with immune checkpoint inhibitor rather than BRAF and MEK leads to improved survival
1. Starting treatment with nivolumab/ipilimumab rather than dabrafenib/trametinib resulted in an...
Read More
Second-line immunosuppression associated with worse outcomes for immune-related adverse events in melanoma
1. Median overall survival was longer in patients receiving steroid-only treatment for adverse...
Read More
United States-based chemotherapy regimen for Ewing sarcoma is more effective and safer than the standard European regimen
1. The United States regimen had greater event-free survival and less associated febrile...
Read More
The experience of spirituality may positively impact the lives of terminal cancer patients
1. In this study, individuals were found to experience peace at the end of life through...
Read More
Variation in prostate cancer screening rates associated with subsequent metastatic prostate cancer incidence
1. A retrospective analysis demonstrated that prostate-specific antigen (PSA) screening has...
Read More
Continued enzalutamide after progression of metastatic prostate cancer improves progression-free survival
1. The median progression-free survival was higher in the enzalutamide vs the placebo group (9.5...
Read More
Adjuvant pembrolizumab improved distant-metastasis free survival and lowered risk of recurrence in melanoma patients
1. In the pembrolizumab arm, distant metastasis-free survival was significantly improved and the...
Read More
Polycystic ovarian syndrome is associated with an increased risk of pancreatic cancer
1. Polycystic ovarian syndrome (PCOS) diagnosis puts women at 1.9 times higher risk of pancreatic...
Read More
Adding weightlifting exercises may further reduce risk of mortality
1. After adjusting for aerobic moderate to vigorous physical activity (MVPA), weightlifting was...
Read More
Fine needle biopsy remains a reliable test for thyroid cancer diagnosis
1. In this systematic review and meta-analysis that included 16,597 patients, fine needle biopsy...
Read More
Atezolizumab does not reduce post-resection recurrence in patients with renal cell carcinoma
1. Atezolizumab was associated with non-significantly increased disease-free survival compared to...
Read More
Nivolumab plus ipilimumab improves recurrence-free survival in patients with resected advanced melanoma
1. 4-year recurrence-free survival was significantly higher with nivolumab plus ipilimumab...
Read More
Optimized vitamin C levels may be associated with mitigated HPV infection risk
1. Though not statistically significant, there was a U-shaped found between vitamin C levels and...
Read More
Stereotactic body radiation does not improve outcomes in patients with advanced Merkel cell carcinoma receiving nivolumab and ipilimumab
1. Objective response rate was not significantly different in patients treated with stereotactic...
Read More