Perioperative Pembrolizumab Improves Survival in Resectable Early-Stage Non-Small Cell Lung Cancer
1. 36-month overall survival and median event-free survival were significantly greater in the...
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Oncology
Statin therapy reduces radiation-induced cardiotoxicity in patients with breast cancer receiving radiotherapy
1. In a cohort of individuals with invasive ductal carcinoma (IDC) that underwent...
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Combination of doxorubicin-trabectedin with trabectedin improves leiomyosarcoma outcomes
1. In patients with advanced leiomyosarcoma, a regimen of doxorubicin-trabectedin was superior to...
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#VisualAbstract: Screening for Helicobacter Pylori to Prevent Gastric Cancer with Fecal Immunochemical Tests
Click here to read this study in JAMA. ©2024 2 Minute Medicine, Inc. All rights reserved. No...
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Extended Pelvic Lymphadenectomy Does Not Improve Survival in MIBC
1. In this randomized controlled trial, extended lymphadenectomy did not improve disease-free or...
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#VisualAbstract: 177Lu-PSMA-617 Prolonged Radiographic Progression-free Survival in Metastatic Prostate Cancer
Click here to read this study in the Lancet. ©2024 2 Minute Medicine, Inc. All rights reserved. No...
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Liver Transplantation + Chemo Improves Survival for Unresectable Colorectal Liver Metastases
1. 5-year survival was significantly greater in the liver transplantation plus chemotherapy group...
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Cabozantinib In Advanced Neuroendocrine Tumors
1. Progression-free survival had a hazard ratio of 0.38 (extrapancreatic NETs) and 0.23...
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Phase II basket trial of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors
1. Treatment of desmoid tumours with dual anti-CTLA-4 and anti-PD-1 blockade with ipilimumab and...
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Overall Survival with Pembrolizumab in Early-Stage Triple-Negative Breast Cancer
1. The 5-year OS rate for pembrolizumab vs placebo was 86.1% vs 81.7% with HR 0.51 (significant)....
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Esophageal Cancer Disparities Declined From 1999 to 2020
From 1999 to 2020, age-adjusted esophageal cancer mortality decreased among Black adults but stabilized among White adults.
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EHR Nudge Can Reduce Unnecessary Sentinel Lymph Node Biopsy
An EHR nudge intervention targeting surgeons can reduce sentinel lymph node biopsy (SLNB) among women who meet the Choosing Wisely criteria for SLNB omission.
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Rare Cancers Associated With Poor Psychological Outcomes
Researchers found an increased risk ratio for depression and anxiety among patients with rare cancers, as well as higher incidences of suicide and PTSD.
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Substantial Disparities Seen for Men in Cancer Cases & Deaths
Disparities seen in cancer incidence and mortality among men across age groups and countries/territories for 2022 are projected to widen further by 2050.
Read MoreDatopotamab deruxtecan may be a novel improvement for inoperable breast cancer
1. Compared to chemotherapy, patients with inoperable hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer receiving the antibody-drug conjugate (ADC) datopotamab deruxtecan...
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Ponsegromab for the Treatment of Cancer Cachexia
1. Ponsegromab at increasing doses resulted in a mean increase in body weight compared to placebo;...
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Naldemedine may be effective for opioid-induced constipation in patients with cancer
1. In a randomized double-blind placebo-controlled study, naldemedine use was associated with...
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False-positive mammography results may deter women from continued screening
1. In this cohort study, women were less likely to return for mammogram screening if their...
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Belzutifan versus Everolimus for Advanced Renal-Cell Carcinoma
1. Median PFS (5.6 months vs 5.6 months) and median OS (21.4 months vs 18.1 months) were similar...
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Impact of different visceral metastatic sites on survival in metastatic prostate cancer patients
1. In a retrospective analysis of 59,875 patients with metastatic prostate cancer, varying...
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