Patient Education Needed to Successfully Integrate PROs Into EHRs
Patients found high value in integrating patient-reported outcomes into electronic health records, but expressed several areas of confusion.
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Oncology
Medication-related osteonecrosis of the jaw is prevalent in patients with breast cancer
1. The cumulative incidence of medication-related osteonecrosis of the jaw (MRONJ) in patients...
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Machine learning algorithm demonstrates ability to appropriately identify cancer patients for serious illness conversations
1. Patel and colleagues conducted a secondary economic analysis of a trial that assigned high-risk...
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Brentuximab-based chemotherapy improves survival and reduces toxicity in patients with advanced Hodgkin lymphoma
1. BrECADD resulted in significantly lower treatment-related morbidity than eBEACOPP. 2....
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Metastasis-Directed Therapy to Systemic Therapy for Oligometastatic Pancreatic Ductal Adenocarcinoma
1. The median progression-free survival in the metastasis-directed therapy arm was 10.3 months vs...
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Alternative lung cancer screening criteria may increase sensitivity versus current guidelines
1. In this modeling study, an alternative set of lung cancer screening criteria was more sensitive...
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Cancer screening costs in the United States may exceed $40 billion annually
1. In the United States, the estimated annual cost of cancer screening was $43 billion, with...
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Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy
1. When comparing corticosteroid peak dose for immunosuppression for anti–PD-1 plus...
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Novel CAR-T Cell Therapy Shows Promise for Pediatric Diffuse Midline Glioma Treatment
1. Approximately 88% of patients with GD2-positive diffuse midline glioma or other progressive CNS...
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Dose-dense adjuvant therapy with epirubicin and cyclophosphamide effective for breast cancer
1. Dose-dense adjuvant chemotherapy involving sequential epirubicin/cyclophosphamide and docetaxel...
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#VisualAbstract Bilateral Masectomy Reduces Risk of Contralateral Breast Cancer But Does Not Reduce the Breast Cancer Mortality Rate
Click here to read this study in the NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No...
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#VisualAbstract: Blinatumomab Improves Survival in MRD-Negative Acute Lymphoblastic Leukemia in Adults
Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No...
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TKI With or Without SRS for Brain Metastases From EGFR/ALK Mutated NSCLC
1. Median overall survival was 41 months in the TKI-only group vs 40 months in the TKI-SRS group,...
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Sintilimab improves survival in advanced non-metastatic nasopharyngeal carcinoma
1. Patients in the sintilimab group reported a significantly greater event-free survival at 36...
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Hormone-modulating therapy decreased risk of dementia in breast cancer patients
1. In a retrospective cohort study of women newly diagnosed with breast cancer, use of hormone...
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#VisualAbstract: Irinotecan and Temozolomide Plus Dasatinib and Rapamycin Improved Progression-Free Survival for Relapsed or Refrcatory Neuroblastoma
Click here to read this study in Lancet Oncology. ©2024 2 Minute Medicine, Inc. All rights...
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Vimseltinib may be promising in treating symptomatic tenosynovial giant cell tumour
1. Tumor response rate at 25 weeks was significantly greater in vimseltinib than placebo. 2. Most...
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Multi-Organ Immune-related Adverse Events from Immune Checkpoint Inhibitors
1. Co-occurrences could be clustered together into 7 clusters based on the predominant organ...
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Tisotumab Vedotin as Second or Third-Line Therapy for Recurrent Cervical Cancer
1. Median overall survival was 11.5 months in the tisotumab vedotin group and 9.5 months in the...
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Immunotherapy-Based Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer
1. The complete response rates (pathological and clinical) were similar (~55%) in both groups. 2....
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