Omitting Axillary Dissection in Breast Cancer with Sentinel-Node Metastases
1. The hazard ratio for recurrence or death comparing sentinel node biopsy only to completion...
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Oncology
#VisualAbstract: Imetelstat improves blood transfusion independence in lower-risk myelodysplastic syndromes
1. Significantly more patients in the imetelstat group achieved RBC transfusion independence at 8...
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#VisualAbstract: Pazopanib does not improve disease-free survival post-metastasectomy for renal cell carcinoma patients
1. Pazopanib did not improve disease-free survival in post-metastasectomy renal cell carcinoma...
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#VisualAbstract: Iptacopan improves hematologic and clinical outcomes in paroxysmal nocturnal hemoglobinuria
1. In two clinical trials, iptacopan in patients with paroxysmal nocturnal hemoglobinuria (PNH)...
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Though associated with rising costs, the majority of publicly-funded cancer medications included in Ontario, Canada are those with substantial survival benefit
1. Roughly 65% of the cancer medication budget is allocated to treatments that provide improvement...
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Neoadjuvant Dual vs Single Checkpoint Inhibitors in High-Risk Melanoma
1. The pathological response rate had an OR of 3.16 when comparing neoadjuvant dual vs single...
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#VisualAbstract: Ribociclib Improves Invasive Disease-Free Survival in Patients with Early Breast Cancer
Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No...
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#VisualAbstract: Preoperative breast MRI may reduce need for adjuvant radiotherapy for women with unifocal breast cancer
1. There were similar rates of ipsilateral invasive recurrence among the postoperative adjuvant...
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Individualized cancer mRNA-based cancer therapy shows benefit in patients with high-risk melanoma on immunotherapy
1. 18-month recurrence-free survival was significantly greater in the combination therapy group...
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Pazopanib does not improve disease-free survival post-metastasectomy for renal cell carcinoma patients
1. Pazopanib did not improve disease-free survival in post-metastasectomy renal cell carcinoma...
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Neoadjuvant Chemoimmunotherapy for Lung Cancer – A Meta-Analysis
1. The overall survival had a significant hazard ratio (0.65) when comparing neoadjuvant...
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Adding ribociclib to endocrine therapy appears to improve invasive disease-free survival in patients with early breast cancer
1. Invasive disease-free survival was significantly higher in patients receiving adjuvant...
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Venetoclax monotherapy effectively treats relapsed or refractory chronic lymphocytic leukemia
1. VENICE-1 observed high response rates (complete or partial remission) in both BCRi-naïve and...
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A cell-free, blood-based DNA screening test for colorectal cancer compared to colonoscopy
1. 83.1% of patients with confirmed colorectal cancer had a positive cfDNA test meeting the...
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Immunotherapy vs Chemoimmunotherapy in Older Adults With Advanced NSCLC
1. Adding chemotherapy to immunotherapy did not prolong OS or PFS, with non-significant...
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Preoperative breast MRI may reduce need for adjuvant radiotherapy for women with unifocal breast cancer
1. There were similar rates of ipsilateral invasive recurrence among the postoperative adjuvant...
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Poor longterm adherence to surveillance guidelines for childhood cancer survivors in Canada
1. In this retrospective, population-based cohort study, adherence to health surveillance...
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Imetelstat improves blood transfusion independence in lower-risk myelodysplastic syndromes
1. Significantly more patients in the imetelstat group achieved RBC transfusion independence at 8...
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Radiation treatment for breast cancer may increase incidence of nonkeratinocyte skin cancer
1. Amongst a cohort of breast cancer survivors, those that were treated with radiation had a...
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Palliative care services are underutilized at end of life in Ontario, Canada
1. In Ontario Canada, only 50% of home care clients received at least 1 or more palliative home...
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